BioCryst Pharmaceuticals, Inc.

BioCryst Pharmaceuticals, Inc.

BCRX·NASDAQ

$8.48

+2.8%
HealthcareBiotechnology

BioCryst Pharmaceuticals, Inc., a biotechnology company, discovers novel, oral, and small-molecule medicines. The company markets peramivir injection, an intravenous neuraminidase inhibitor for the treatment of acute uncomplicated influenza under the RAPIVAB, RAPIACTA, and PERAMIFLU names; and ORLADEYO, an oral serine protease inhibitor to treat hereditary angioedema. It is also developing BCX9930, an oral factor D inhibitor, which is in Phase II clinical trial for complement-mediated diseases; BCX9250, an oral activin receptor-like kinase-2 inhibitor that is in Phase I clinical trial to treat fibrodysplasia ossificans progressiva; and Galidesivir, a RNA dependent-RNA polymerase inhibitor, which is in Phase I clinical trial to treat various RNA viruses, including Marburg, Yellow Fever, Ebola, and Zika. The company has collaborations and in-license relationships with the Torii Pharmaceutical Co., Ltd.; Seqirus UK Limited; Shionogi & Co., Ltd.; Green Cross Corporation; Mundipharma International Holdings Limited; National Institute of Allergy and Infectious Diseases; Biomedical Advanced Research and Development Authority; the U.S. Department of Health and Human Services; and The University of Alabama at Birmingham, as well as Albert Einstein College of Medicine of Yeshiva University and Industrial Research, Ltd. BioCryst Pharmaceuticals, Inc. was founded in 1986 and is headquartered in Durham, North Carolina.

At a Glance

Live Snapshot
Market Cap$1.78B
EPS1.2600
P/E Ratio6.73
Earnings Date08/03/2026
93.94%
Return on Invested Capital
-13602%
3Y-383.0%
5Y-240.0%
10Y-223.0%
-221.45%
Return on Equity
-1286%
3Y-364.0%
5Y-123.0%
10Y-2373.0%
51.32%
Return on Assets
-383%
3Y-214.0%
5Y-194.0%
10Y-184.0%
BioCryst Pharmaceuticals, Inc.

BioCryst Pharmaceuticals, Inc. Management Team

BCRX · NASDAQ
MJ

Mr. John D. Bluth

Chief Communications Officer

Born 1973(Age 53)
male
MJ

Ms. Jinky Ang Rosselli

Chief Data & Insights Officer

female
DW

Dr. William P. Sheridan MBBS

Chief Development Officer

Compensation

$784,089

Born 1955(Age 71)
DY

Dr. Yarlagadda S. Babu Ph.D.

Chief Discovery Officer

Compensation

$691,450

Born 1953(Age 73)
MJ

Mr. Jon P. Stonehouse

Chief Executive Officer, President & Executive Director and Interim Chief Financial Officer, Principal Accounting Officer

Compensation

$1,639,233

Born 1961(Age 65)
male
MS

Ms. Stephanie Angelini

Chief People Officer

female
DH

Dr. Helen M. Thackray FAAP, M.D.

Chief Research & Development Officer

Compensation

$1,246,067

Born 1968(Age 58)
MP

Mr. Philip George

Chief Strategy Officer

male
MC

Mr. Charles K. Gayer

Senior Vice President & Chief Commercial Officer

Compensation

$1,052,427

Born 1971(Age 55)
male
MA

Ms. Alane P. Barnes

Senior Vice President, Chief Legal Officer & Corporate Secretary

Compensation

$1,015,590

Born 1966(Age 60)
female
bcrx

BioCryst Pharmaceuticals, Inc. Insider Positioning

BCRX · NASDAQ

During the last 12 months, insiders have purchased $239K and sold $4.14M worth of BCRX shares, resulting in $3.90M of net selling activity.

3 Months

Bought

0

0.00

Sold

273.6K

2.57M

Net Activity

-2.6M

-$2.57M

3-6 Months

Bought

0

0.00

Sold

43.0K

328.82K

Net Activity

-329K

-$329K

6-9 Months

Bought

0

0.00

Sold

171.3K

1.23M

Net Activity

-1.2M

-$1.23M

9-12 Months

Bought

42.7K

238.88K

Sold

0

0.00

Net Activity

+239K

+$239K

Top Buyers

1
HT

Heggie Theresa

Director

40.0K shares1 transactions

$216K

2
FS

Frank Steven

Director

1.4K shares1 transactions

$11K

3
MAE

Mckee Amy E

Director

676 shares1 transactions

$6K

4
MV

Milano Vincent

Director

676 shares1 transactions

$6K

Top Sellers

1
BAP

Barnes Alane P

Officer: Chief Legal Officer

417.2K shares7 transactions

$3.46M

2
HT

Heggie Theresa

Director

49.9K shares1 transactions

$505K

3
MAE

Mckee Amy E

Director

11.2K shares1 transactions

$100K

4
SM

Sanders Machelle

Director

9.6K shares1 transactions

$69K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $3.90M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.06:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$2.57M

Heavy recent selling activity. Recent insider sales notably exceed purchases—may warrant investigation into company developments.

Insider Participation

Balanced

4 insider buyers and 4 sellers. Equal participation suggests mixed or neutral insider views.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.

SEC Filings

BCRX - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 23, 2026
June 11, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 24, 2025
June 12, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 25, 2024
June 12, 2024
2024
DEF 14A

DEF 14A

N/A

April 27, 2023
April 27, 2023
 
DEF 14A

DEF 14A 2022

N/A

April 25, 2022
June 07, 2022
2022
DEF 14A

DEF 14A 2021

N/A

April 13, 2021
May 25, 2021
2021
DEF 14A

DEF 14A 2020

N/A

March 31, 2020
May 12, 2020
2020
DEF 14A

DEF 14A 2019

N/A

April 17, 2019
May 29, 2019
2019
DEF 14A

DEF 14A 2018

N/A

September 28, 2018
October 30, 2018
2018
DEF 14A

DEF 14A 2018

N/A

May 10, 2018
June 20, 2018
2018
Showing 1 to 10 of 31 filings