BioCryst Pharmaceuticals, Inc.

BioCryst Pharmaceuticals, Inc.

BCRXยทNASDAQ

$8.48

+2.8%
HealthcareBiotechnology

BioCryst Pharmaceuticals, Inc., a biotechnology company, discovers novel, oral, and small-molecule medicines. The company markets peramivir injection, an intravenous neuraminidase inhibitor for the treatment of acute uncomplicated influenza under the RAPIVAB, RAPIACTA, and PERAMIFLU names; and ORLADEYO, an oral serine protease inhibitor to treat hereditary angioedema. It is also developing BCX9930, an oral factor D inhibitor, which is in Phase II clinical trial for complement-mediated diseases; BCX9250, an oral activin receptor-like kinase-2 inhibitor that is in Phase I clinical trial to treat fibrodysplasia ossificans progressiva; and Galidesivir, a RNA dependent-RNA polymerase inhibitor, which is in Phase I clinical trial to treat various RNA viruses, including Marburg, Yellow Fever, Ebola, and Zika. The company has collaborations and in-license relationships with the Torii Pharmaceutical Co., Ltd.; Seqirus UK Limited; Shionogi & Co., Ltd.; Green Cross Corporation; Mundipharma International Holdings Limited; National Institute of Allergy and Infectious Diseases; Biomedical Advanced Research and Development Authority; the U.S. Department of Health and Human Services; and The University of Alabama at Birmingham, as well as Albert Einstein College of Medicine of Yeshiva University and Industrial Research, Ltd. BioCryst Pharmaceuticals, Inc. was founded in 1986 and is headquartered in Durham, North Carolina.

At a Glance

Live Snapshot
Market Cap$1.78B
EPS1.2600
P/E Ratio6.73
Earnings Date08/03/2026
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BioCryst Pharmaceuticals, Inc. Street Expectations Map

BCRX ยท NASDAQ

Wall Street analysts project that BCRX stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 16.86, with estimates ranging from a low of 8.00 to a high of 25.00.

Lowest Target
8.00
-5.65%
Consensus Target
16.86
98.83%
Highest Target
25.00
194.83%

The consensus 1-year price target stands at 16.86, with estimates ranging from a low of 8.00 to a high of 25.00.

Analyst Consensus Analysis

Upside Potential

+98.8%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

100.8% spread

High uncertainty. Very wide target spread indicates significant disagreement among analystsโ€”major valuation uncertainty or transformation underway.

Risk-Reward Profile

34.45x

Favorable risk-reward. Potential upside significantly exceeds downside risk, offering asymmetric return profile attractive for risk-tolerant investors.

Analyst Conviction

Low

High uncertainty: Wide dispersion indicates analysts struggle to agree on valuationโ€”proceed with caution and independent analysis.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

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BioCryst Pharmaceuticals, Inc. Forward Estimates of Revenue

BCRX ยท NASDAQ
Latest Revenue
874.84M
FY 2025
Avg Estimate
671.03M
FY 2026
Estimate Range
645.57M - 696.50M
Analyst Spread

Forward Growth Analysis

Projected Growth-23.3%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread8%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

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BioCryst Pharmaceuticals, Inc. Forward Estimates of Net Income

BCRX ยท NASDAQ
Latest Net Income
263.86M
FY 2025
Avg Estimate
-584.15M
FY 2026
Estimate Range
-618.13M - -550.18M
Analyst Spread

Forward Growth Analysis

Projected Growth-321.4%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread12%

Reasonable estimate spread indicates general agreement with normal forecast variance.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

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BioCryst Pharmaceuticals, Inc. Forward Estimates of EPS

BCRX ยท NASDAQ
Latest EPS
1.26
FY 2025
Avg Estimate
$-2.68
FY 2026
Estimate Range
$-2.83 - $-2.52
Analyst Spread

Forward Growth Analysis

Projected Growth-312.5%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread12%

Reasonable estimate spread indicates general agreement with normal forecast variance.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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BioCryst Pharmaceuticals, Inc. Forward Estimates of EBIT

BCRX ยท NASDAQ
Latest EBIT
346.26M
FY 2025
Avg Estimate
-167.83M
FY 2026
Estimate Range
-174.20M - -161.46M
Analyst Spread

Forward Growth Analysis

Projected Growth-148.5%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread8%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

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BioCryst Pharmaceuticals, Inc. Forward Estimates of EBITDA

BCRX ยท NASDAQ
Latest EBITDA
347.65M
FY 2025
Avg Estimate
-165.20M
FY 2026
Estimate Range
-171.47M - -158.93M
Analyst Spread

Forward Growth Analysis

Projected Growth-147.5%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread8%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

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BioCryst Pharmaceuticals, Inc. Forward Estimates of SG&A Expense

BCRX ยท NASDAQ
Latest SG&A Expense
348.65M
FY 2025
Avg Estimate
399.78M
FY 2026
Estimate Range
384.61M - 414.95M
Analyst Spread

Forward Growth Analysis

Projected Growth+14.7%

Solid growth trajectory indicates healthy business performance and competitive positioning.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread8%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

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BioCryst Pharmaceuticals, Inc. Insider Positioning

BCRX ยท NASDAQ

During the last 12 months, insiders have purchased $239K and sold $4.14M worth of BCRX shares, resulting in $3.90M of net selling activity.

3 Months

Bought

0

0.00

Sold

273.6K

2.57M

Net Activity

-2.6M

-$2.57M

3-6 Months

Bought

0

0.00

Sold

43.0K

328.82K

Net Activity

-329K

-$329K

6-9 Months

Bought

0

0.00

Sold

171.3K

1.23M

Net Activity

-1.2M

-$1.23M

9-12 Months

Bought

42.7K

238.88K

Sold

0

0.00

Net Activity

+239K

+$239K

Top Buyers

1
HT

Heggie Theresa

Director

40.0K sharesโ€ข1 transactions

$216K

2
FS

Frank Steven

Director

1.4K sharesโ€ข1 transactions

$11K

3
MAE

Mckee Amy E

Director

676 sharesโ€ข1 transactions

$6K

4
MV

Milano Vincent

Director

676 sharesโ€ข1 transactions

$6K

Top Sellers

1
BAP

Barnes Alane P

Officer: Chief Legal Officer

417.2K sharesโ€ข7 transactions

$3.46M

2
HT

Heggie Theresa

Director

49.9K sharesโ€ข1 transactions

$505K

3
MAE

Mckee Amy E

Director

11.2K sharesโ€ข1 transactions

$100K

4
SM

Sanders Machelle

Director

9.6K sharesโ€ข1 transactions

$69K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $3.90M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.06:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$2.57M

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

Balanced

4 insider buyers and 4 sellers. Equal participation suggests mixed or neutral insider views.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.