aTyr Pharma, Inc.

aTyr Pharma, Inc.

ATYRยทNASDAQ

$0.55

-4.9%
HealthcareBiotechnology

aTyr Pharma, Inc., a biotherapeutics company, engages in the discovery and development of medicines based on novel immunological pathways in the United States. Its lead therapeutic candidate is efzofitimod, a selective modulator of NRP2 that is in Phase III clinical trial for pulmonary sarcoidosis; and in Phase 1b/2a clinical trial for treatment of other interstitial lung diseases (ILDs), such as chronic hypersensitivity pneumonitis and connective tissue disease related ILD. The company is developing ATYR0101, a fusion protein derived from a domain of aspartyl-tRNA synthetase that is in preclinical development for the treatment of fibrosis; and ATYR0750, a domain of alanyl-tRNA synthetase for the treatment of liver disorders. It has collaboration and license agreement with Kyorin Pharmaceutical Co., Ltd. for the development and commercialization of efzofitimod for ILDs in Japan. aTyr Pharma, Inc. was incorporated in 2005 and is headquartered in San Diego, California.

At a Glance

Live Snapshot
Market Cap$53.59M
EPS-0.8000
P/E Ratio-0.98
Earnings Date08/06/2026
-96.45%
Return on Invested Capital
18%
3Y+72.0%
5Y+104.0%
10Y+18.0%
-109.84%
Return on Equity
20%
3Y+73.0%
5Y+114.0%
10Y+19.0%
-78.71%
Return on Assets
19%
3Y+66.0%
5Y+88.0%
10Y+10.0%
aTyr Pharma, Inc.

aTyr Pharma, Inc. Management Team

ATYR ยท NASDAQ
MJ

Ms. Jill M. Broadfoot CPA

Chief Financial Officer

Compensation

$585,723

Born 1962(Age 64)
female
MA

Ms. Ashlee Dunston

Director of Investor Relations & Corporate Communications

female
MN

Ms. Nancy E. Denyes Krueger J.D.

General Counsel & Corporate Secretary

Compensation

$568,865

Born 1968(Age 58)
female
MD

Ms. Dalia R. Rayes M.B.A.

Head of Commercial, Global Efzofitimod Franchise

female
DS

Dr. Sanjay S. Shukla M.D., M.S.

President, Chief Executive Officer & Director

Compensation

$838,762

Born 1972(Age 54)
MP

Mr. Peter Villiger

Vice President of Corporate Development

male
MD

Ms. Danielle Campbell

Vice President of Human Resource

female
DL

Dr. Leslie Nangle Ph.D.

Vice President of Research

DJ

Dr. Jayant Aphale MBA, Ph.D.

Vice President of Technical Operations

Born 1960(Age 66)
atyr

aTyr Pharma, Inc. Insider Positioning

ATYR ยท NASDAQ

During the last 12 months, insiders have purchased $961K and sold $6K worth of ATYR shares, resulting in $955K of net buying activity.

3 Months

Bought

100.0K

49.63K

Sold

0

0.00

Net Activity

+50K

+$50K

3-6 Months

Bought

0

0.00

Sold

6.4K

6.27K

Net Activity

-6K

-$6K

6-9 Months

Bought

1.0M

911.80K

Sold

0

0.00

Net Activity

+912K

+$912K

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

1
SP

Schimmel Paul

Director

1.1M sharesโ€ข3 transactions

$961K

Top Sellers

1
SS

Shukla Sanjay

Director, Officer: President And Ceo

3.7K sharesโ€ข1 transactions

$4K

2
BJM

Broadfoot Jill Marie

Officer: Chief Financial Officer

1.6K sharesโ€ข1 transactions

$2K

3
DN

Denyes Nancy

Officer: General Counsel

1.1K sharesโ€ข1 transactions

$1K

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $955K net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

153.44:1

Exceptional buy/sell ratio. Buying dramatically outweighs sellingโ€”one of the strongest possible insider signals.

Recent Trend (3 Months)

$50K

Very strong recent buying momentum. Recent insider purchases significantly outpace sales, suggesting near-term optimism.

Insider Participation

High Selling

3 insider sellers vs. 1 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Sustained buying momentum: Consistent net buying over multiple quarters suggests insiders maintain conviction in the company's prospects. This is particularly meaningful if buying continued through market volatility.

SEC Filings

ATYR - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

March 26, 2026
March 26, 2026
2026
DEF 14A

DEF 14A 2025

N/A

March 19, 2025
March 19, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 05, 2024
May 22, 2024
2024
DEF 14A

DEF 14A 2023

N/A

March 29, 2023
May 17, 2023
2023
DEF 14A

DEF 14A 2022

N/A

March 22, 2022
April 26, 2022
2022
DEF 14A

DEF 14A 2021

N/A

March 24, 2021
April 28, 2021
2021
DEF 14A

DEF 14A 2020

N/A

April 02, 2020
May 06, 2020
2020
DEF 14A

DEF 14A 2019

N/A

March 28, 2019
May 08, 2019
2019
DEF 14A

DEF 14A 2018

N/A

April 03, 2018
May 15, 2018
2018
DEF 14A

DEF 14A 2017

N/A

March 30, 2017
May 09, 2017
2017
Showing 1 to 10 of 11 filings