ATYR - NASDAQ
aTyr Pharma, Inc.
$0.54
+5.8%aTyr Pharma, Inc., a biotherapeutics company, engages in the discovery and development of medicines based on novel immunological pathways in the United States. Its lead therapeutic candidate is efzofitimod, a selective modulator of NRP2 that is in Phase III clinical trial for pulmonary sarcoidosis; and in Phase 1b/2a clinical trial for treatment of other interstitial lung diseases (ILDs), such as chronic hypersensitivity pneumonitis and connective tissue disease related ILD. The company is developing ATYR0101, a fusion protein derived from a domain of aspartyl-tRNA synthetase that is in preclinical development for the treatment of fibrosis; and ATYR0750, a domain of alanyl-tRNA synthetase for the treatment of liver disorders. It has collaboration and license agreement with Kyorin Pharmaceutical Co., Ltd. for the development and commercialization of efzofitimod for ILDs in Japan. aTyr Pharma, Inc. was incorporated in 2005 and is headquartered in San Diego, California.
At a Glance
Live SnapshotaTyr Pharma, Inc. Profit Bridge
Profitability Analysis
Gross Margin
Negative gross margin indicates the company is losing money on each sale—unsustainable long-term.
Operating Margin
Operating losses indicate the core business is unprofitable. Requires restructuring or revenue growth.
Net Profit Margin
Net losses indicate the company is burning cash. Sustainability depends on path to profitability.
Profitability Insight
High margin compression: Large gap between gross and net margins suggests operational inefficiencies or heavy debt burden. Focus on expense management and deleveraging.
aTyr Pharma, Inc. Income Statement
ATYR • NASDAQ
| aTyr Pharma, Inc. Income Statement | Dec 2025 | Dec 2024 | Dec 2023 | Dec 2022 | Dec 2021 | Dec 2020 | Dec 2019 | Dec 2018 | Dec 2017 | Dec 2016 | Dec 2015 | Dec 2014 | Dec 2013 | Dec 2012 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
REVENUE | ||||||||||||||
190K | 235K | 353K | 10.4M | 0.0 | 10.5M | 422K | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | |
GROSS PROFIT | ||||||||||||||
(1.6M) | (0.0) | (0.0) | (1.7M) | (1.3M) | (17.3M) | (14M) | (746K) | (713K) | (900K) | (0.0) | (0.0) | (0.0) | (540K) | |
-1.4M | 235K | 353K | 8.7M | -1.3M | -6.8M | -13.6M | -746K | -713K | -900K | 0.0 | 0.0 | 0.0 | -540K | |
OPERATING INCOME | ||||||||||||||
(76.3M) | (68.1M) | (55.3M) | (55.1M) | (32.7M) | (9.1M) | (22M) | (32.1M) | (46.4M) | (58.4M) | (47.6M) | (23.6M) | (19.5M) | (12.1M) | |
(17.6M) | (13.8M) | (13M) | (12.3M) | (10.8M) | (9.1M) | (8M) | (11.7M) | (16.4M) | (14.2M) | (13.1M) | (6.8M) | (5.7M) | (4.3M) | |
(60.2M) | (54.4M) | (42.3M) | (42.8M) | (23.3M) | (17.3M) | (14M) | (20.4M) | (30.1M) | (44.2M) | (34.5M) | (16.8M) | (13.8M) | (7.7M) | |
-77.6M | -67.9M | -54.9M | -46.4M | -34M | -15.9M | -23M | -32.8M | -47.1M | -59.3M | -47.6M | -23.6M | -19.5M | -12.6M | |
PRE-TAX INCOME | ||||||||||||||
(0.0) | (0.0) | (0.0) | (0.0) | (0.0) | (0.0) | (0.0) | (0.0) | (0.0) | (0.0) | (0.0) | (832K) | (444K) | (272K) | |
0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | -832K | -444K | -272K | |
-1.6M | (0.0) | (0.0) | (0.0) | -1.3M | -17.3M | (0.0) | (0.0) | (0.0) | (0.0) | (0.0) | (0.0) | (0.0) | (0.0) | |
3.5M | 3.9M | 4.5M | 1.1M | 238K | -319K | -785K | -1.7M | -1.1M | 1.4M | -357K | -796K | -472K | -261K | |
-74.1M | -64M | -50.4M | -45.3M | -33.8M | -16.2M | -23.8M | -34.5M | -48.2M | -57.9M | -48M | -24.4M | -20M | -12.9M | |
NET INCOME | ||||||||||||||
(0.0) | (0.0) | (0.0) | (0.0) | (0.0) | (0.0) | -160K | (0.0) | (0.0) | -49K | (0.0) | (0.0) | (0.0) | (0.0) | |
-74.1M | -64M | -50.4M | -45.3M | -33.8M | -16.2M | -23.6M | -34.5M | -48.2M | -57.9M | -48M | -24.4M | -20M | -17.6M |
SEC Filings
ATYR - Filing history and reports
| Filing Type | Filing Date | Period Ending | Fiscal Year | Actions |
|---|---|---|---|---|
8-K 8-K 2026 N/A | June 01, 2026 | June 01, 2026 | 2026 | |
10-Q 10-Q 2026 Q1 Q1 | May 15, 2026 | March 31, 2026 | 2026 | |
8-K 8-K 2026 N/A | May 15, 2026 | May 15, 2026 | 2026 | |
8-K 8-K 2026 N/A | May 11, 2026 | May 11, 2026 | 2026 | |
DEF 14A DEF 14A 2026 N/A | March 26, 2026 | March 26, 2026 | 2026 | |
10-K 10-K 2025 FY FY | March 05, 2026 | December 31, 2025 | 2025 | |
8-K 8-K 2026 N/A | March 05, 2026 | March 05, 2026 | 2026 | |
8-K 8-K 2025 N/A | December 05, 2025 | December 04, 2025 | 2025 | |
8-K 8-K 2025 N/A | November 06, 2025 | November 06, 2025 | 2025 | |
10-Q 10-Q 2025 Q3 Q3 | November 06, 2025 | September 30, 2025 | 2025 |
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Research Paths
Snapshot
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Value Model
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Statements
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Earnings Call
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Dividends
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Analyst Expectations
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