aTyr Pharma, Inc.

aTyr Pharma, Inc.

ATYRยทNASDAQ

$0.55

-4.9%
HealthcareBiotechnology

aTyr Pharma, Inc., a biotherapeutics company, engages in the discovery and development of medicines based on novel immunological pathways in the United States. Its lead therapeutic candidate is efzofitimod, a selective modulator of NRP2 that is in Phase III clinical trial for pulmonary sarcoidosis; and in Phase 1b/2a clinical trial for treatment of other interstitial lung diseases (ILDs), such as chronic hypersensitivity pneumonitis and connective tissue disease related ILD. The company is developing ATYR0101, a fusion protein derived from a domain of aspartyl-tRNA synthetase that is in preclinical development for the treatment of fibrosis; and ATYR0750, a domain of alanyl-tRNA synthetase for the treatment of liver disorders. It has collaboration and license agreement with Kyorin Pharmaceutical Co., Ltd. for the development and commercialization of efzofitimod for ILDs in Japan. aTyr Pharma, Inc. was incorporated in 2005 and is headquartered in San Diego, California.

At a Glance

Live Snapshot
Market Cap$53.59M
EPS-0.8000
P/E Ratio-0.98
Earnings Date08/06/2026
atyr

aTyr Pharma, Inc. Street Expectations Map

ATYR ยท NASDAQ

Wall Street analysts project that ATYR stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 5.13, with estimates ranging from a low of 1.00 to a high of 17.00.

Lowest Target
1.00
82.95%
Consensus Target
5.13
838.53%
Highest Target
17.00
3010.14%

The consensus 1-year price target stands at 5.13, with estimates ranging from a low of 1.00 to a high of 17.00.

Analyst Consensus Analysis

Upside Potential

+838.5%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

311.9% spread

High uncertainty. Very wide target spread indicates significant disagreement among analystsโ€”major valuation uncertainty or transformation underway.

Analyst Conviction

Low

High uncertainty: Wide dispersion indicates analysts struggle to agree on valuationโ€”proceed with caution and independent analysis.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

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aTyr Pharma, Inc. Forward Estimates of Revenue

ATYR ยท NASDAQ
Latest Revenue
190.00K
FY 2025
Avg Estimate
3.85M
FY 2026
Estimate Range
3.85M - 3.85M
Analyst Spread

Forward Growth Analysis

Projected Growth+1928.9%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

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aTyr Pharma, Inc. Forward Estimates of Net Income

ATYR ยท NASDAQ
Latest Net Income
-74.12M
FY 2025
Avg Estimate
-54.01M
FY 2026
Estimate Range
-54.82M - -50.79M
Analyst Spread

Forward Growth Analysis

Projected Growth+27.1%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread7%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

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aTyr Pharma, Inc. Forward Estimates of EPS

ATYR ยท NASDAQ
Latest EPS
-0.80
FY 2025
Avg Estimate
$-0.57
FY 2026
Estimate Range
$-0.59 - $-0.55
Analyst Spread

Forward Growth Analysis

Projected Growth+28.5%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread8%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

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aTyr Pharma, Inc. Forward Estimates of EBIT

ATYR ยท NASDAQ
Latest EBIT
-77.63M
FY 2025
Avg Estimate
-2.31M
FY 2026
Estimate Range
-2.31M - -2.31M
Analyst Spread

Forward Growth Analysis

Projected Growth+97.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

atyr

aTyr Pharma, Inc. Forward Estimates of EBITDA

ATYR ยท NASDAQ
Latest EBITDA
-76.07M
FY 2025
Avg Estimate
-2.31M
FY 2026
Estimate Range
-2.31M - -2.31M
Analyst Spread

Forward Growth Analysis

Projected Growth+97.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

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aTyr Pharma, Inc. Forward Estimates of SG&A Expense

ATYR ยท NASDAQ
Latest SG&A Expense
17.60M
FY 2025
Avg Estimate
146.64M
FY 2026
Estimate Range
146.64M - 146.64M
Analyst Spread

Forward Growth Analysis

Projected Growth+733.3%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

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aTyr Pharma, Inc. Insider Positioning

ATYR ยท NASDAQ

During the last 12 months, insiders have purchased $961K and sold $6K worth of ATYR shares, resulting in $955K of net buying activity.

3 Months

Bought

100.0K

49.63K

Sold

0

0.00

Net Activity

+50K

+$50K

3-6 Months

Bought

0

0.00

Sold

6.4K

6.27K

Net Activity

-6K

-$6K

6-9 Months

Bought

1.0M

911.80K

Sold

0

0.00

Net Activity

+912K

+$912K

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

1
SP

Schimmel Paul

Director

1.1M sharesโ€ข3 transactions

$961K

Top Sellers

1
SS

Shukla Sanjay

Director, Officer: President And Ceo

3.7K sharesโ€ข1 transactions

$4K

2
BJM

Broadfoot Jill Marie

Officer: Chief Financial Officer

1.6K sharesโ€ข1 transactions

$2K

3
DN

Denyes Nancy

Officer: General Counsel

1.1K sharesโ€ข1 transactions

$1K

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $955K net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

153.44:1

Exceptional buy/sell ratio. Buying dramatically outweighs sellingโ€”one of the strongest possible insider signals.

Recent Trend (3 Months)

$50K

Very strong recent buying momentum. Recent insider purchases significantly outpace sales, suggesting near-term optimism.

Insider Participation

High Selling

3 insider sellers vs. 1 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Sustained buying momentum: Consistent net buying over multiple quarters suggests insiders maintain conviction in the company's prospects. This is particularly meaningful if buying continued through market volatility.