Agios Pharmaceuticals, Inc.

Agios Pharmaceuticals, Inc.

AGIO·NASDAQ

$27.68

-1.1%
HealthcareBiotechnology

Agios Pharmaceuticals, Inc., a biopharmaceutical company, engages in the discovery and development of medicines in the field of cellular metabolism and adjacent areas of biology. The company offers PYRUKYND (mitapivat) an activator of both wild-type and a variety of mutant pyruvate kinase, PK, enzymes for the treatment of hemolytic anemias; and AG-946 that is in Phase I clinical study for treating hemolytic anemias and other indications. Agios Pharmaceuticals, Inc. was incorporated in 2007 and is headquartered in Cambridge, Massachusetts.

At a Glance

Live Snapshot
Market Cap$1.65B
EPS-7.1200
P/E Ratio-3.89
Earnings Date07/30/2026
-38.18%
Return on Invested Capital
53%
3Y+17.0%
5Y-13.0%
10Y+1.0%
-34.60%
Return on Equity
-179%
3Y+64.0%
5Y-58.0%
10Y-37.0%
-31.82%
Return on Assets
-179%
3Y+70.0%
5Y-17.0%
10Y-1.0%
Agios Pharmaceuticals, Inc.

Agios Pharmaceuticals, Inc. Management Team

AGIO · NASDAQ
MT

Ms. Tsveta Milanova

Chief Commercial Officer

Compensation

$836,643

Born 1977(Age 49)
female
MB

Mr. Brian M. Goff M.B.A.

Chief Executive Officer & Director

Compensation

$1,553,274

Born 1969(Age 57)
male
MC

Ms. Cecilia Jones

Chief Financial Officer

Compensation

$802,574

Born 1975(Age 51)
female
DS

Dr. Sarah Gheuens M.D., Ph.D.

Chief Medical Officer and Head of Research & Development

Compensation

$927,572

Born 1980(Age 46)
DC

Dr. Craig B. Thompson M.D.

Co-Founder

Born 1953(Age 73)
DL

Dr. Lewis clayton Cantley Ph.D.

Co-Founder

Compensation

$50,000

Born 1949(Age 77)
DS

Dr. Shin-San Su Ph.D.

Co-Founder

Born 1956(Age 70)
DT

Dr. Tak Wah Mak D.Sc., FRSC, Ph.D.

Co-Founder

Born 1946(Age 80)
MJ

Mr. James William Burns

Corporate Secretary & Chief Legal Officer

Compensation

$815,732

Born 1978(Age 48)
male
MT

Mr. T. J. Washburn

Vice President, Controller & Principal Accounting Officer

Born 1982(Age 44)
male
agio

Agios Pharmaceuticals, Inc. Insider Positioning

AGIO · NASDAQ

During the last 12 months, insiders have purchased $5K and sold $1.62M worth of AGIO shares, resulting in $1.61M of net selling activity.

3 Months

Bought

0

0.00

Sold

22.2K

769.80K

Net Activity

-770K

-$770K

3-6 Months

Bought

0

0.00

Sold

26.2K

731.70K

Net Activity

-732K

-$732K

6-9 Months

Bought

200

5.00K

Sold

2.7K

116.20K

Net Activity

-111K

-$111K

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

1
GS

Gheuens Sarah

Officer: Chief Medical Officer

200 shares1 transactions

$5K

Top Sellers

1
GB

Goff Brian

Director, Officer: Chief Executive Officer

18.7K shares3 transactions

$569K

2
GS

Gheuens Sarah

Officer: Chief Medical Officer

5.4K shares2 transactions

$209K

3
BJW

Burns James William

Officer: Chief Legal Officer

6.2K shares2 transactions

$193K

4
MT

Milanova Tsveta

Officer: Chief Commercial Officer

6.1K shares2 transactions

$191K

5
VK

Viswanadhan Krishnan

Officer: Chief Corp Dev & Strategy

5.9K shares2 transactions

$185K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $1.61M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$770K

Heavy recent selling activity. Recent insider sales notably exceed purchases—may warrant investigation into company developments.

Insider Participation

High Selling

5 insider sellers vs. 1 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.

SEC Filings

AGIO - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 24, 2026
June 18, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 25, 2025
June 18, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 26, 2024
June 20, 2024
2024
DEF 14A

DEF 14A

N/A

April 26, 2023
April 26, 2023
 
DEF 14A

DEF 14A 2022

N/A

April 28, 2022
June 21, 2022
2022
DEF 14A

DEF 14A 2021

N/A

April 08, 2021
May 20, 2021
2021
DEF 14A

DEF 14A 2020

N/A

April 16, 2020
May 28, 2020
2020
DEF 14A

DEF 14A 2019

N/A

April 18, 2019
May 29, 2019
2019
DEF 14A

DEF 14A 2018

N/A

April 18, 2018
May 31, 2018
2018
DEF 14A

DEF 14A 2017

N/A

April 24, 2017
June 13, 2017
2017
Showing 1 to 10 of 13 filings