Agios Pharmaceuticals, Inc.

Agios Pharmaceuticals, Inc.

AGIOยทNASDAQ

$27.68

-1.1%
HealthcareBiotechnology

Agios Pharmaceuticals, Inc., a biopharmaceutical company, engages in the discovery and development of medicines in the field of cellular metabolism and adjacent areas of biology. The company offers PYRUKYND (mitapivat) an activator of both wild-type and a variety of mutant pyruvate kinase, PK, enzymes for the treatment of hemolytic anemias; and AG-946 that is in Phase I clinical study for treating hemolytic anemias and other indications. Agios Pharmaceuticals, Inc. was incorporated in 2007 and is headquartered in Cambridge, Massachusetts.

At a Glance

Live Snapshot
Market Cap$1.65B
EPS-7.1200
P/E Ratio-3.89
Earnings Date07/30/2026
agio

Agios Pharmaceuticals, Inc. Street Expectations Map

AGIO ยท NASDAQ

Wall Street analysts project that AGIO stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 42.00, with estimates ranging from a low of 36.00 to a high of 50.00.

Lowest Target
36.00
30.06%
Consensus Target
42.00
51.73%
Highest Target
50.00
80.64%

The consensus 1-year price target stands at 42.00, with estimates ranging from a low of 36.00 to a high of 50.00.

Analyst Consensus Analysis

Upside Potential

+51.7%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

33.3% spread

Good consensus alignment. Moderate target spread reflects general agreement on value drivers with some variance in assumptions.

Analyst Conviction

High

Positive outlook with reasonable agreement. Analysts generally optimistic about prospects with manageable uncertainty.

Market Sentiment Insight

Monitor and evaluate: Current analyst consensus suggests limited conviction or near-term catalysts. Stay informed on company developments and reassess positioning as new information emerges.

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Agios Pharmaceuticals, Inc. Forward Estimates of Revenue

AGIO ยท NASDAQ
Latest Revenue
54.03M
FY 2025
Avg Estimate
120.21M
FY 2026
Estimate Range
98.32M - 146.69M
Analyst Spread

Forward Growth Analysis

Projected Growth+122.5%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage7 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread40%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

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Agios Pharmaceuticals, Inc. Forward Estimates of Net Income

AGIO ยท NASDAQ
Latest Net Income
-412.78M
FY 2025
Avg Estimate
-360.23M
FY 2026
Estimate Range
-416.98M - -316.77M
Analyst Spread

Forward Growth Analysis

Projected Growth+12.7%

Solid growth trajectory indicates healthy business performance and competitive positioning.

Analyst Coverage7 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread28%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

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Agios Pharmaceuticals, Inc. Forward Estimates of EPS

AGIO ยท NASDAQ
Latest EPS
-7.12
FY 2025
Avg Estimate
$-6.13
FY 2026
Estimate Range
$-7.19 - $-5.46
Analyst Spread

Forward Growth Analysis

Projected Growth+13.9%

Solid growth trajectory indicates healthy business performance and competitive positioning.

Analyst Coverage8 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread28%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

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Agios Pharmaceuticals, Inc. Forward Estimates of EBIT

AGIO ยท NASDAQ
Latest EBIT
-472.13M
FY 2025
Avg Estimate
-72.12M
FY 2026
Estimate Range
-88.01M - -58.99M
Analyst Spread

Forward Growth Analysis

Projected Growth+84.7%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage7 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread40%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

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Agios Pharmaceuticals, Inc. Forward Estimates of EBITDA

AGIO ยท NASDAQ
Latest EBITDA
-466.95M
FY 2025
Avg Estimate
-72.12M
FY 2026
Estimate Range
-88.01M - -58.99M
Analyst Spread

Forward Growth Analysis

Projected Growth+84.6%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage7 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread40%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

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Agios Pharmaceuticals, Inc. Forward Estimates of SG&A Expense

AGIO ยท NASDAQ
Latest SG&A Expense
180.28M
FY 2025
Avg Estimate
520.42M
FY 2026
Estimate Range
425.67M - 635.08M
Analyst Spread

Forward Growth Analysis

Projected Growth+188.7%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage7 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread40%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

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Agios Pharmaceuticals, Inc. Insider Positioning

AGIO ยท NASDAQ

During the last 12 months, insiders have purchased $5K and sold $1.62M worth of AGIO shares, resulting in $1.61M of net selling activity.

3 Months

Bought

0

0.00

Sold

22.2K

769.80K

Net Activity

-770K

-$770K

3-6 Months

Bought

0

0.00

Sold

26.2K

731.70K

Net Activity

-732K

-$732K

6-9 Months

Bought

200

5.00K

Sold

2.7K

116.20K

Net Activity

-111K

-$111K

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

1
GS

Gheuens Sarah

Officer: Chief Medical Officer

200 sharesโ€ข1 transactions

$5K

Top Sellers

1
GB

Goff Brian

Director, Officer: Chief Executive Officer

18.7K sharesโ€ข3 transactions

$569K

2
GS

Gheuens Sarah

Officer: Chief Medical Officer

5.4K sharesโ€ข2 transactions

$209K

3
BJW

Burns James William

Officer: Chief Legal Officer

6.2K sharesโ€ข2 transactions

$193K

4
MT

Milanova Tsveta

Officer: Chief Commercial Officer

6.1K sharesโ€ข2 transactions

$191K

5
VK

Viswanadhan Krishnan

Officer: Chief Corp Dev & Strategy

5.9K sharesโ€ข2 transactions

$185K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $1.61M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$770K

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

High Selling

5 insider sellers vs. 1 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.