Oruka Therapeutics, Inc.

Healthcare

NASDAQ:ORKA · NASDAQ Global Market

Market Cap $2.65B Beta -0.30 P/E (TTM) -33.9
$72.34 +0.65%

+$0.46 today

52W Low $10.77High $91.00

Vol 2.99M · Avg 1.55M

EPS (TTM) -$2.11Biotechnology

Management

Put operating results in leadership context

Review returns on capital, executive background, insider transactions, and growth quality to judge whether management is compounding value well.

Return Metrics

ROE, ROIC & ROA over time

Management
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ROE

-22.3%

avg -57.2%

ROIC

-25.8%

avg -58.5%

ROA

-21.6%

avg -50.9%

Analysis

ROA is currently the strongest return metric at -21.6% versus its period average of -50.9%. 0 of 3 return metrics are above their quality threshold, which helps indicate how efficiently the company turns capital and assets into profit.

Management

Key executives, compensation & ownership

Management
NameTitleCompensationTenureAgeShares OwnedOwnership %

Lawrence Otto Klein

President, Chief Executive Officer & Director$1.08M43$925,580.002.47%

Joana Goncalves

Chief Medical Officer$730,980.0052$37,165.000.10%

Paul T. Quinlan

General Counsel & Secretary$730,980.0063$31,034.000.08%

Rajiv Panwar

Senior VP and Head of Chemistry, Manufacturing & Controls

Alan Lada

VP of IR & Capital Markets

Arjun Agarwal

Senior Vice President of Finance & Treasurer50$16,899.000.05%

Christopher Finch

Senior VP and Head of Business Development & Strategy$35,000.000.09%

Laura Sandler

Chief Operating Officer48$236,384.000.63%

Insider Trading

SEC Form 4 transactions — last 12 months

Management

Buys

0

$0.00

Sells

53

$13.58M

Net Sentiment

$13.58M

Net selling

Most Active

Goncalves Joana

22 transactions

DateInsiderTypeSharesPriceValue
Jun 15, 2026

Goncalves Joana

Direct

Sell5.1K$69.42$351,547.44
Jun 15, 2026

Goncalves Joana

Direct

Sell300$70.62$21,186.99
Jun 15, 2026

Goncalves Joana

Direct

Sell947$69.69$65,996.43
Jun 15, 2026

Klein Lawrence Otto

Direct

Sell1.7K$69.69$120,494.01
Jun 15, 2026

Sandler Laura Lee

Direct

Sell600$69.69$41,814.00
Jun 15, 2026

Quinlan Paul T

Direct

Sell733$69.69$51,082.77
Jun 15, 2026

Agarwal Arjun

Direct

Sell395$69.69$27,527.55
Jun 15, 2026

Goncalves Joana

Direct

Sell1.6K$68.38$111,876.06
Jun 12, 2026

Dambkowski Carl

Direct

Sell12.6K$70.11$882,181.55
Jun 12, 2026

Agarwal Arjun

Direct

Sell1.9K$68.34$127,047.59

1–10 of 53

Analysis

Insiders reported 0 buys worth $0.00 and 53 sells worth $13.58M over the last 12 months. That adds up to net selling of $13.58M. Goncalves Joana was the most active insider with 22 transactions.

Growth Analysis

Historical CAGR & forward analyst estimates

Metric 10yr 5yr3yr Fwd Est.
EPSN/AN/AN/A
N/A5 analysts
RevenueN/AN/AN/A
N/A3 analysts
Net IncomeN/AN/AN/A
N/A3 analysts
EBITN/AN/AN/A
N/A3 analysts

Analysis

Analysis will appear once historical growth or forward estimates are available for this company.

Who manages ORKA?

Oruka Therapeutics, Inc. (ORKA) lists 8 active executives. The top listed executive is Joana Goncalves, Chief Medical Officer.

Are ORKA insiders buying or selling?

Recent insider activity shows net buying of $15.14M.

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