Gyre Therapeutics, Inc.

Gyre Therapeutics, Inc.

Healthcare

NASDAQ:GYRE · NASDAQ Capital Market

Market Cap $589.93M Beta 4.92 P/E (TTM) -88.3
$6.25 -0.15%

+$0.00 today

52W Low $5.44High $9.42

Vol 0.06M · Avg 0.09M

EPS (TTM) -$0.07Biotechnology

Management

Put operating results in leadership context

Review returns on capital, executive background, insider transactions, and growth quality to judge whether management is compounding value well.

Return Metrics

ROE, ROIC & ROA over time

Management
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ROE

4.7%

avg 0.1%

ROIC

5.3%

avg -51.0%

ROA

3.0%

avg -43.7%

Analysis

ROIC is currently the strongest return metric at 5.3% versus its period average of -51.0%. 0 of 3 return metrics are above their quality threshold, which helps indicate how efficiently the company turns capital and assets into profit.

Management

Key executives, compensation & ownership

Management
NameTitleCompensationTenureAgeShares OwnedOwnership %

Ping Zhang

Interim Chief Executive Officer & Executive Chair$578,861.0053$0.00<0.01%

Weiguo Ye

Chief Operating Officer$563,414.0048$700,000.000.72%

Han Ying

Senior Vice President of Science$353,315.0060$120,000.000.12%

Ruoyu Chen

Chief Information Officer$285,583.0055$50,000.000.05%

Ying Luo

CEO, President & Director$85,000.0061$120,000.000.12%

Thomas W. Eastling

Chief Financial Officer$50,000.0067$33,271.000.03%

Jing Liu

Senior Vice President of Platform Chemistry

Mark Marino

Senior Vice President of Clinical Development

Michael Plewe

Senior Vice President - Medicinal Chemistry

Jialiang Wang

Executive VP & GM$0.00<0.01%

Joshua Bergmann

General Counsel & Corporate Secretary$50,000.000.05%

Songjiang Ma

President & Director70$2.81M2.89%

Seth Goldblum

Senior Vice President of Corporate Development

Yue Xiong

Chief Scientific Officer$0.00<0.01%

Insider Trading

SEC Form 4 transactions — last 12 months

Management

Buys

0

$0.00

Sells

14

$826,364.76

Net Sentiment

$826,364.76

Net selling

Most Active

Ye Weiguo

12 transactions

DateInsiderTypeSharesPriceValue
Jun 11, 2026

Ye Weiguo

Direct

Sell2.8K$6.17$17,276.00
Jun 10, 2026

Ye Weiguo

Direct

Sell6.4K$6.21$39,855.78
Jun 9, 2026

Ye Weiguo

Direct

Sell14.5K$6.14$89,030.00
Jun 5, 2026

Ye Weiguo

Direct

Sell15.4K$6.40$98,566.40
Jun 4, 2026

Ye Weiguo

Direct

Sell19.6K$6.13$119,994.75
May 26, 2026

Ye Weiguo

Direct

Sell4.0K$6.10$24,400.40
May 22, 2026

Ye Weiguo

Direct

Sell3.5K$6.08$21,280.00
May 21, 2026

Ye Weiguo

Direct

Sell12.8K$6.15$78,843.00
May 19, 2026

Ye Weiguo

Direct

Sell9.1K$6.37$58,094.40
May 18, 2026

Ye Weiguo

Direct

Sell200$6.62$1,324.00

1–10 of 14

Analysis

Insiders reported 0 buys worth $0.00 and 14 sells worth $826,364.76 over the last 12 months. That adds up to net selling of $826,364.76. Ye Weiguo was the most active insider with 12 transactions.

Growth Analysis

Historical CAGR & forward analyst estimates

Metric 10yr 5yr3yr Fwd Est.
EPSN/AN/AN/A
N/A1 analysts
RevenueN/AN/A-68.8%
+41.1% (15yr)1 analysts
Net IncomeN/AN/AN/A
N/A1 analysts
EBITN/AN/AN/A
N/A1 analysts

Analysis

Recent growth has been strongest in Revenue at -68.8% over three years. Forward estimates point to Revenue at +41.1% (15yr), giving you a quick check on whether expectations are accelerating or cooling.

Who manages GYRE?

Gyre Therapeutics, Inc. (GYRE) lists 14 active executives. The top listed executive is Han Ying, Senior Vice President of Science.

Are GYRE insiders buying or selling?

Recent insider activity shows net buying of $13.43M.

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