Enliven Therapeutics, Inc.

Healthcare

NASDAQ:ELVN · NASDAQ Global Select

Market Cap $2.73B Beta 0.40 P/E (TTM) -28.4

$45.10 -0.27%

-$0.12 today

52W Low $14.79High $48.53

Vol 2.16M · Avg 1.35M

EPS (TTM) -$1.57Biotechnology

Management

Put operating results in leadership context

Review returns on capital, executive background, insider transactions, and growth quality to judge whether management is compounding value well.

Return Metrics

ROE, ROIC & ROA over time

Management

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ROE

-22.6%

avg 1.6%

ROIC

-26.0%

avg -49.4%

ROA

-21.8%

avg -42.3%

Analysis

ROA is currently the strongest return metric at -21.8% versus its period average of -42.3%. 0 of 3 return metrics are above their quality threshold, which helps indicate how efficiently the company turns capital and assets into profit.

Management

Key executives, compensation & ownership

Management

Name	Title	Compensation	Tenure	Age	Shares Owned	Ownership %
Samuel S. Kintz	Co-Founder & Head of Pipeline	$956,094.00	—	40	$890,392.00	1.46%
Helen Louise Collins	Chief Medical Officer	$726,420.00	—	63	$25,000.00	0.04%
Joseph Lyssikatos	Co-Founder & Research Fellow	$709,400.00	—	61	$112,500.00	0.18%
Richard A. Fair	CEO, President & Director	$672,656.00	—	57	$22,647.00	0.04%
Benjamin Hohl	Chief Financial Officer & Head of Corporate Development	$667,894.00	—	37	$51,000.00	0.08%
Anish Patel	Co-Founder & Chief Operating Officer	—	—	45	$120,000.00	0.20%
Galya D. Blachman	Chief Legal Officer & Head of Business Development	—	—	49	$17,126.00	0.03%

Insider Trading

SEC Form 4 transactions — last 12 months

Management

Buys

$0.00

Sells

$27.39M

Net Sentiment

$27.39M

Net selling

Most Active

Lyssikatos Joseph P

19 transactions

Date	Insider	Type	Shares	Price	Value
Jun 15, 2026	ORBIMED ADVISORS LLC Indirect	Sell	272.3K	$45.02	$12,259,936.44
Jun 15, 2026	ORBIMED ADVISORS LLC Indirect	Sell	9.1K	$45.02	$409,051.72
Jun 5, 2026	Kunkel Lori Anne Direct	Sell	7.8K	$34.28	$266,659.45
Jun 5, 2026	Kunkel Lori Anne Direct	Sell	1.9K	$35.36	$66,012.08
Jun 5, 2026	Kunkel Lori Anne Direct	Sell	354	$35.82	$12,679.82
May 18, 2026	Collins Helen Louise Direct	Sell	223	$41.21	$9,188.76
May 18, 2026	Collins Helen Louise Direct	Sell	3.5K	$39.53	$137,380.65
May 18, 2026	Collins Helen Louise Direct	Sell	1.3K	$40.25	$52,401.98
Apr 17, 2026	Collins Helen Louise Direct	Sell	140	$45.81	$6,413.50
Apr 17, 2026	Collins Helen Louise Direct	Sell	2.4K	$47.39	$114,635.44

1–10 of 73

Analysis

Insiders reported 0 buys worth $0.00 and 73 sells worth $27.39M over the last 12 months. That adds up to net selling of $27.39M. Lyssikatos Joseph P was the most active insider with 19 transactions.