Crescent Biopharma, Inc.

Crescent Biopharma, Inc.

Healthcare

NASDAQ:CBIO · NASDAQ Capital Market

Market Cap $487.75M Beta 1.15 P/E (TTM) -3.3
$17.69 -2.69%

-$0.49 today

52W Low $8.72High $27.41

Vol 0.11M · Avg 0.28M

EPS (TTM) -$5.33Biotechnology

Management

Put operating results in leadership context

Review returns on capital, executive background, insider transactions, and growth quality to judge whether management is compounding value well.

Return Metrics

ROE, ROIC & ROA over time

Management
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ROE

-75.8%

avg -26.6%

ROIC

-74.6%

avg -72.7%

ROA

-64.1%

avg -59.7%

Analysis

ROA is currently the strongest return metric at -64.1% versus its period average of -59.7%. 0 of 3 return metrics are above their quality threshold, which helps indicate how efficiently the company turns capital and assets into profit.

Management

Key executives, compensation & ownership

Management
NameTitleCompensationTenureAgeShares OwnedOwnership %

Joshua T. Brumm

Chief Executive Officer & Director$1.25M48$323,517.001.17%

Jonathan McNeill

President & Chief Operating Officer$871,682.0041$11,050.000.04%

Ellie Im

Chief Medical Officer$847,841.0048$65,190.000.24%

Wenjie Cheng

Senior Vice President of Technical Operations

Richard William Scalzo

Chief Financial Officer40$57,688.000.21%

Ryan Lynch

Senior Vice President of Finance, Treasurer & Chief Accounting Officer42$33,512.000.12%

Christopher Doughty

Chief Business Officer38$58,855.000.21%

Barbara H. Bispham

General Counsel & Corporate Secretary39$72,185.000.26%

Amy Reilly

Chief Communications Officer52

Jan Pinkas

Chief Scientific Officer57$70,025.000.25%

Insider Trading

SEC Form 4 transactions — last 12 months

Management

Buys

2

$18.24M

Sells

0

$0.00

Net Sentiment

+$18.24M

Net buying

Most Active

Fairmount Funds Management LLC

2 transactions

DateInsiderTypeSharesPriceValue
Dec 4, 2025

Fairmount Funds Management LLC

Indirect

Buy1.36M$13.41$18,237,600.00
Dec 4, 2025

Fairmount Funds Management LLC

Indirect

Buy131.4K$0.00$131.43

Analysis

Insiders reported 2 buys worth $18.24M and 0 sells worth $0.00 over the last 12 months. That adds up to net buying of $18.24M. Fairmount Funds Management LLC was the most active insider with 2 transactions.

Growth Analysis

Historical CAGR & forward analyst estimates

Metric 10yr 5yr3yr Fwd Est.
EPSN/AN/AN/A
N/A1 analysts
RevenueN/AN/A+9.6%
+9.4% (15yr)3 analysts
Net IncomeN/AN/AN/A
N/A3 analysts
EBITN/AN/AN/A
N/A3 analysts

Analysis

Recent growth has been strongest in Revenue at +9.6% over three years. Forward estimates point to Revenue at +9.4% (15yr), giving you a quick check on whether expectations are accelerating or cooling.

Who manages CBIO?

Crescent Biopharma, Inc. (CBIO) lists 10 active executives. The top listed executive is Jonathan McNeill, President & Chief Operating Officer.

Are CBIO insiders buying or selling?

Recent insider activity shows net buying of $39.99M.

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