Alnylam Pharmaceuticals, Inc.

Alnylam Pharmaceuticals, Inc.

Healthcare

NASDAQ:ALNY · NASDAQ Global Select

Market Cap $38.64B Beta 0.27 P/E (TTM) 65.3
$282.85 -2.01%

-$5.82 today

52W Low $281.77High $495.55

Vol 1.40M · Avg 1.11M

EPS (TTM)$4.34
Biotechnology

Income Statement

Follow revenue through to earnings

Review sales, margins, expenses, and profit trends to see what is actually driving reported earnings over time.

Earnings Waterfall

Revenue to Net Income

Key Ratios

EPS$4.21
Gross Margin80.8%
Net Margin11.5%
P/E Ratio6.0
P/S Ratio47.1

Analysis

$4.3B of revenue converted into $577.2M of net income for the selected period. Gross margin is 80.8% and net margin is 11.5%, showing how much revenue survives after costs and taxes. EPS is $4.21, tying the income statement back to per-share earnings.

Income Statement

Annual data · 5 periods

MetricFY2025FY2024FY2023FY2022FY2021FY2020FY2019FY2018
Revenue
$3.7B
+65.2%
$2.2B
+23.0%
$1.8B
+76.2%
$1.0B
+22.9%
$844.3M
$809.6M$921.6M$731.2M
Cost of Revenue
$677.2M
+109.4%
$323.4M
+4.2%
$310.4M
+83.9%
$168.8M
+20.5%
$140.1M
$725.6M$804.0M$882.4M
Gross Profit
$3.0B
+57.8%
$1.9B
+26.8%
$1.5B
+74.8%
$868.6M
+23.4%
$704.1M
$8.9B$7.6B$6.2B
Gross Margin
81.8%
-3.8pp
85.6%
+2.6pp
83.0%
-0.7pp
83.7%
+0.3pp
83.4%
9.8%28.9%38.3%
Research & Development
$1.3B
+17.6%
$1.1B
+12.1%
$1.0B
+13.7%
$883.0M
+11.5%
$792.2M
$983.2M$1.3B$490.4M
Selling, General & Admin
$1.2B
+24.1%
$975.5M
+22.6%
$795.6M
+3.2%
$770.7M
+24.2%
$620.6M
$620.6M$923.0M-$1.5B
Operating Expenses
$2.5B
+20.6%
$2.1B
+16.8%
$1.8B
+8.9%
$1.7B
+17.0%
$1.4B
$5.3B$7.0B$8.7B
Depreciation & Amortization
$55.7M
-1.8%
$56.7M
+4.8%
$54.1M
+21.6%
$44.5M
-6.5%
$47.6M
$374.2M$1.2B$631.8M
EBITDA
$631.4M
+453.1%
-$178.8M
+30.7%
-$258.2M
+72.1%
-$926.6M
-40.1%
-$661.6M
-$15.2B$6.8B$9.3B
EBITDA Margin
17.0%
+25.0pp
-8.0%
+6.2pp
-14.1%
+75.2pp
-89.3%
-11.0pp
-78.4%
5.6%46.3%42.0%
Operating Income
$501.6M
+383.6%
-$176.9M
+37.3%
-$282.2M
+64.1%
-$785.1M
-10.8%
-$708.7M
$12.3B$14.0B-$15.7B
Operating Margin
13.5%
+21.4pp
-7.9%
+7.6pp
-15.4%
+60.2pp
-75.7%
+8.3pp
-83.9%
16.6%24.1%22.0%
Interest Income
$111.5M
-8.6%
$122.0M
+27.7%
$95.6M
+285.2%
$24.8M
+1471.1%
$1.6M
-$1.5B-$1.6B$405.0M
Interest Expense
$252.6M
+78.1%
$141.9M
+17.0%
$121.2M
-22.3%
$156.0M
+9.1%
$143.0M
$1.1B$1.0B$1.2B
Other Income / Expenses
-$178.4M
+11.0%
-$200.5M
-32.5%
-$151.3M
+55.7%
-$341.9M
-138.3%
-$143.5M
-$1.5B$1.4B$1.2B
Income Before Tax
$323.2M
+185.6%
-$377.4M
+13.0%
-$433.5M
+61.5%
-$1.1B
-32.3%
-$852.1M
$3.3B$4.9B$3.6B
Pre-Tax Margin
8.7%
+25.5pp
-16.8%
+6.9pp
-23.7%
+84.9pp
-108.6%
-7.7pp
-100.9%
20.8%18.7%26.2%
Income Tax Expense
$9.4M
+109.5%
-$99.2M
-1575.4%
$6.7M
+61.5%
$4.2M
+512.2%
$680.0K
$1.3B-$1.6B$745.2M
Net Income
$313.7M
+212.8%
-$278.2M
+36.8%
-$440.2M
+61.1%
-$1.1B
-32.6%
-$852.8M
$4.9B$4.8B$4.7B
Net Margin
8.4%
+20.8pp
-12.4%
+11.7pp
-24.1%
+85.0pp
-109.0%
-8.0pp
-101.0%
12.4%17.5%22.5%
EPS (Basic)
$2
+209.6%
-$2
+38.1%
-$4
+62.2%
-$9
-29.2%
-$7
$400.8M$703.2M$1.3B
EPS (Diluted)
$2
+206.9%
-$2
+38.1%
-$4
+62.2%
-$9
-29.2%
-$7
$766.2M$609.4M$452.6M
Weighted Avg Shares
$131.0M
+2.6%
$127.7M
+2.2%
$124.9M
+2.6%
$121.7M
+2.7%
$118.5M
$757.8M$925.8M$1.1B
Weighted Avg Shares (Diluted)
$134.7M
+5.5%
$127.7M
+2.2%
$124.9M
+2.6%
$121.7M
+2.7%
$118.5M
$1.2B$924.4M$678.0M

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SEC Filings

Recent regulatory filings

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How much revenue does ALNY generate?

Alnylam Pharmaceuticals, Inc. (ALNY) reported $3.71B of revenue in fiscal 2025.

Is ALNY profitable?

Alnylam Pharmaceuticals, Inc. (ALNY) reported $313.75M of net income, with a net margin of 8.4%.

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