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Healthcare - Biotechnology - NASDAQ - US
$ 0.17
-5.56 %
$ 11.1 M
Market Cap
-0.11
P/E
1. INTRINSIC VALUE

Lyra Therapeutics, Inc., a clinical-stage therapeutics company, focuses on the development and commercialization of novel integrated drug and delivery solutions for the localized treatment of patients with ear, nose, and throat diseases. It's XTreo technology platform is designed to deliver medicines directly to the affected tissue for sustained periods with a single administration. The company's product candidates include LYR-210, an anti-inflammatory implantable drug matrix for the treatment of chronic rhinosinusitis (CRS), which is in Phase II clinical trial; and LYR-220 for CRS patients with and without nasal polyps. The company was formerly known as 480 Biomedical, Inc. and changed its name to Lyra Therapeutics, Inc.[ Read More ]

The intrinsic value of one LYRA stock under the base case scenario is HIDDEN Compared to the current market price of 0.17 USD, Lyra Therapeutics, Inc. is HIDDEN

2. FUNDAMENTAL ANALYSIS

Price Chart LYRA

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FINANCIALS
1.56 M REVENUE
14.31%
-67.1 M OPERATING INCOME
-19.21%
-62.7 M NET INCOME
-13.39%
-63.3 M OPERATING CASH FLOW
-45.91%
-12.6 M INVESTING CASH FLOW
80.64%
65.7 M FINANCING CASH FLOW
-31.75%
195 K REVENUE
-67.39%
-12.4 M OPERATING INCOME
74.59%
-11.9 M NET INCOME
75.33%
-16.2 M OPERATING CASH FLOW
18.81%
8.14 M INVESTING CASH FLOW
-77.50%
-23 K FINANCING CASH FLOW
74.16%
Balance Sheet Decomposition Lyra Therapeutics, Inc.
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Current Assets 105 M
Cash & Short-Term Investments 103 M
Receivables 0
Other Current Assets 2.07 M
Non-Current Assets 37.8 M
Long-Term Investments 0
PP&E 35.3 M
Other Non-Current Assets 2.5 M
Current Liabilities 19.6 M
Accounts Payable 3.13 M
Short-Term Debt 10.9 M
Other Current Liabilities 5.6 M
Non-Current Liabilities 33.6 M
Long-Term Debt 21.4 M
Other Non-Current Liabilities 12.1 M
EFFICIENCY
Earnings Waterfall Lyra Therapeutics, Inc.
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Revenue 1.56 M
Cost Of Revenue 48 M
Gross Profit -46.5 M
Operating Expenses 20.6 M
Operating Income -67.1 M
Other Expenses -4.44 M
Net Income -62.7 M
RATIOS
-2982.73% GROSS MARGIN
-2982.73%
-4308.09% OPERATING MARGIN
-4308.09%
-4023.11% NET MARGIN
-4023.11%
-70.10% ROE
-70.10%
-43.96% ROA
-43.96%
-70.83% ROIC
-70.83%
FREE CASH FLOW ANALYSIS
Free Cash Flow Analysis Lyra Therapeutics, Inc.
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Net Income -62.7 M
Depreciation & Amortization 278 K
Capital Expenditures -1.05 M
Stock-Based Compensation 5.89 M
Change in Working Capital -4.88 M
Others -7.24 M
Free Cash Flow -64.4 M
3. WALL STREET ANALYSTS ESTIMATES
Wall Street Analysts Price Targets Lyra Therapeutics, Inc.
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Wall Street analysts predict an average 1-year price target for LYRA of $0.5 , with forecasts ranging from a low of $0.5 to a high of $0.5 .
LYRA Lowest Price Target Wall Street Target
0.5 USD 194.12%
LYRA Average Price Target Wall Street Target
0.5 USD 194.12%
LYRA Highest Price Target Wall Street Target
0.5 USD 194.12%
4. DIVIDEND ANALYSIS
0.00% DIVIDEND YIELD
0 USD DIVIDEND PER SHARE
5. COMPETITION
6. Ownership
Insider Ownership Lyra Therapeutics, Inc.
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Sold
0-3 MONTHS
0 USD 0
3-6 MONTHS
0 USD 0
6-9 MONTHS
0 USD 0
9-12 MONTHS
0 USD 0
Bought
0 USD 0
0-3 MONTHS
0 USD 0
3-6 MONTHS
0 USD 0
6-9 MONTHS
0 USD 0
9-12 MONTHS
Date Value Insider Amount Avg Price
1 year ago
Nov 10, 2023
Bought 74.1 K USD
Waksal Harlan
Executive Chair
+ 25000
2.9638 USD
1 year ago
May 31, 2023
Bought 2.92 M USD
NBVM GP, LLC
10 percent owner
+ 1203612
2.43 USD
1 year ago
May 31, 2023
Bought 981 K USD
NBVM GP, LLC
10 percent owner
+ 403858
2.43 USD
1 year ago
May 31, 2023
Bought 481 K USD
NBVM GP, LLC
10 percent owner
+ 197946
2.43 USD
1 year ago
May 31, 2023
Bought 1.61 M USD
NBVM GP, LLC
10 percent owner
+ 601806
2.673 USD
1 year ago
May 31, 2023
Bought 540 K USD
NBVM GP, LLC
10 percent owner
+ 201929
2.673 USD
1 year ago
May 31, 2023
Bought 265 K USD
NBVM GP, LLC
10 percent owner
+ 98973
2.673 USD
1 year ago
May 31, 2023
Bought 2.92 M USD
ANDERSON EDWARD T
director, 10 percent owner:
+ 1203612
2.43 USD
1 year ago
May 31, 2023
Bought 981 K USD
ANDERSON EDWARD T
director, 10 percent owner:
+ 403858
2.43 USD
1 year ago
May 31, 2023
Bought 481 K USD
ANDERSON EDWARD T
director, 10 percent owner:
+ 197946
2.43 USD
1 year ago
May 31, 2023
Bought 1.61 M USD
ANDERSON EDWARD T
director, 10 percent owner:
+ 601806
2.673 USD
1 year ago
May 31, 2023
Bought 540 K USD
ANDERSON EDWARD T
director, 10 percent owner:
+ 201929
2.673 USD
1 year ago
May 31, 2023
Bought 265 K USD
ANDERSON EDWARD T
director, 10 percent owner:
+ 98973
2.673 USD
1 year ago
May 31, 2023
Bought 9 M USD
PERCEPTIVE ADVISORS LLC
director, 10 percent owner:
+ 3610832
2.4925 USD
1 year ago
May 31, 2023
Bought 4.83 M USD
PERCEPTIVE ADVISORS LLC
director, 10 percent owner:
+ 1805416
2.673 USD
2 years ago
Jun 10, 2022
Bought 20.2 K USD
MERRIFIELD C ANN
director:
+ 4000
5.05 USD
2 years ago
May 13, 2022
Bought 1.64 K USD
MERRIFIELD C ANN
director:
+ 328
5 USD
2 years ago
May 13, 2022
Bought 16.8 K USD
MERRIFIELD C ANN
Director
+ 3500
4.813 USD
2 years ago
Apr 12, 2022
Bought 25 M USD
EDELMAN JOSEPH
director:
+ 5924170
4.22 USD
2 years ago
Apr 12, 2022
Bought 25 M USD
PERCEPTIVE ADVISORS LLC
director, 10 percent owner:
+ 5924170
4.22 USD
2 years ago
Apr 12, 2022
Bought 4.54 M USD
NBVM GP, LLC
10 percent owner
+ 1076851
4.22 USD
2 years ago
Apr 12, 2022
Bought 3.23 M USD
North Bridge Venture Management VI, L.P.
director:
+ 765010
4.22 USD
2 years ago
Apr 12, 2022
Bought 3.23 M USD
NBVM GP, LLC
10 percent owner
+ 765010
4.22 USD
2 years ago
Apr 12, 2022
Bought 2.23 M USD
NBVM GP, LLC
10 percent owner
+ 527806
4.22 USD
2 years ago
Apr 12, 2022
Bought 4.54 M USD
ANDERSON EDWARD T
director:
+ 1076851
4.22 USD
2 years ago
Apr 12, 2022
Bought 3.23 M USD
ANDERSON EDWARD T
director, 10 percent owner:
+ 765010
4.22 USD
2 years ago
Apr 12, 2022
Bought 2.23 M USD
ANDERSON EDWARD T
director, 10 percent owner:
+ 527806
4.22 USD
2 years ago
Apr 12, 2022
Bought 500 K USD
ANDERSON EDWARD T
director, 10 percent owner:
+ 118483
4.22 USD
2 years ago
Apr 12, 2022
Bought 1 M USD
Waksal Harlan
Executive Chair
+ 236966
4.22 USD
3 years ago
Jun 17, 2021
Bought 31.4 K USD
MERRIFIELD C ANN
Director
+ 3500
8.9699 USD
3 years ago
Dec 16, 2020
Bought 9.96 K USD
snyderman nancy lynn MD
Director
+ 1025
9.72 USD
4 years ago
May 05, 2020
Bought 10 M USD
PERCEPTIVE ADVISORS LLC
director, 10 percent owner:
+ 625000
16 USD
4 years ago
May 05, 2020
Sell 271 K USD
Soleus Private Equity GP I, LLC
10 percent owner
- 16909
16 USD
4 years ago
May 05, 2020
Bought 2.48 M USD
Soleus Private Equity GP I, LLC
10 percent owner
+ 155000
16 USD
4 years ago
May 05, 2020
Bought 1.88 M USD
NBVM GP, LLC
10 percent owner
+ 117439
16 USD
4 years ago
May 05, 2020
Sell 182 K USD
NBVM GP, LLC
10 percent owner
- 11360
16 USD
4 years ago
May 05, 2020
Bought 1.2 M USD
NBVM GP, LLC
10 percent owner
+ 75000
16 USD
4 years ago
May 05, 2020
Sell 116 K USD
NBVM GP, LLC
10 percent owner
- 7255
16 USD
4 years ago
May 05, 2020
Bought 921 K USD
NBVM GP, LLC
10 percent owner
+ 57561
16 USD
4 years ago
May 05, 2020
Sell 89.1 K USD
NBVM GP, LLC
10 percent owner
- 5568
16 USD
4 years ago
May 05, 2020
Bought 1.88 M USD
ANDERSON EDWARD T
director, 10 percent owner:
+ 117439
16 USD
4 years ago
May 05, 2020
Sell 182 K USD
ANDERSON EDWARD T
director, 10 percent owner:
- 11360
16 USD
4 years ago
May 05, 2020
Bought 1.2 M USD
ANDERSON EDWARD T
director, 10 percent owner:
+ 75000
16 USD
4 years ago
May 05, 2020
Sell 116 K USD
ANDERSON EDWARD T
director, 10 percent owner:
- 7255
16 USD
4 years ago
May 05, 2020
Bought 921 K USD
ANDERSON EDWARD T
director, 10 percent owner:
+ 57561
16 USD
4 years ago
May 05, 2020
Sell 89.1 K USD
ANDERSON EDWARD T
director, 10 percent owner:
- 5568
16 USD
4 years ago
May 05, 2020
Bought 965 K USD
Polaris Venture Management Co. V, L.L.C.
10 percent owner
+ 60308
16 USD
4 years ago
May 05, 2020
Sell 149 K USD
Polaris Venture Management Co. V, L.L.C.
10 percent owner
- 9334
16 USD
4 years ago
May 05, 2020
Bought 18.8 K USD
Polaris Venture Management Co. V, L.L.C.
10 percent owner
+ 1176
16 USD
4 years ago
May 05, 2020
Sell 2.91 K USD
Polaris Venture Management Co. V, L.L.C.
10 percent owner
- 182
16 USD
4 years ago
May 05, 2020
Bought 9.65 K USD
Polaris Venture Management Co. V, L.L.C.
10 percent owner
+ 603
16 USD
4 years ago
May 05, 2020
Sell 1.5 K USD
Polaris Venture Management Co. V, L.L.C.
10 percent owner
- 94
16 USD
4 years ago
May 05, 2020
Bought 6.61 K USD
Polaris Venture Management Co. V, L.L.C.
10 percent owner
+ 413
16 USD
4 years ago
May 05, 2020
Sell 1.02 K USD
Polaris Venture Management Co. V, L.L.C.
10 percent owner
- 64
16 USD
7. News
Lyra Therapeutics, Inc. (LYRA) Reports Q3 Loss, Lags Revenue Estimates Lyra Therapeutics, Inc. (LYRA) came out with a quarterly loss of $0.18 per share versus the Zacks Consensus Estimate of a loss of $0.23. This compares to loss of $0.27 per share a year ago. zacks.com - 4 days ago
Lyra Therapeutics Reports Third Quarter 2024 Financial Results and Provides Corporate Update WATERTOWN, Mass., Nov. 12, 2024 (GLOBE NEWSWIRE) --   Lyra Therapeutics, Inc.  (Nasdaq: LYRA) (“Lyra” or the “Company”), a clinical-stage biotechnology company developing long-acting, anti-inflammatory sinonasal implants for the treatment of chronic rhinosinusitis (CRS), today reported its financial results for the third quarter ended September 30, 2024 and provided a corporate update. globenewswire.com - 4 days ago
Lyra Therapeutics Fully Enrolls Pivotal Phase 3 ENLIGHTEN 2 Trial of LYR-210 for the Treatment of Chronic Rhinosinusitis -- Topline Results Expected Q2 2025 -- WATERTOWN, Mass., Oct. 15, 2024 (GLOBE NEWSWIRE) -- Lyra Therapeutics, Inc. (Nasdaq: LYRA) (“Lyra” or the “Company”), a clinical-stage biotechnology company developing long-acting anti-inflammatory therapies for the localized treatment of chronic rhinosinusitis (CRS), today announced that the pivotal Phase 3 ENLIGHTEN 2 clinical trial of LYR-210 in adult patients with CRS who have not had prior ethmoid sinus surgery, is fully enrolled. LYR-210 is a bioresorbable nasal implant designed to deliver six months of continuous anti-inflammatory medication (mometasone furoate) to the sinonasal passages for the treatment of CRS. Topline results from ENLIGHTEN 2 are expected in Q2 2025. globenewswire.com - 1 month ago
Lyra Therapeutics to Present Study Results for LYR-210 and LYR-220 in Two Presentations at the ARS and AAO-HNS Annual Meetings WATERTOWN, Mass., Sept. 27, 2024 (GLOBE NEWSWIRE) -- Lyra Therapeutics, Inc. (Nasdaq: LYRA), (“Lyra” or the “Company”), a clinical-stage biotechnology company developing long-acting anti-inflammatory therapies for the localized treatment of chronic rhinosinusitis (CRS), today announced that the Company will present results from the Phase 3 ENLIGHTEN 1 study for LYR-210, the company's lead product candidate for CRS, at the 70th Annual Meeting of the American Rhinologic Society (ARS), taking place September 27-28 in Miami. The Company will also present additional results from the Phase 2 BEACON study for LYR-220 in adult patients with CRS who have had prior ethmoid sinus surgery at the Annual Meeting of the American Academy of Otolaryngology–Head and Neck Surgery (AAO-HNS), taking place September 28 - October 1 in Miami. globenewswire.com - 1 month ago
Lyra Therapeutics, Inc. (LYRA) Reports Q2 Loss, Tops Revenue Estimates Lyra Therapeutics, Inc. (LYRA) came out with a quarterly loss of $0.29 per share versus the Zacks Consensus Estimate of a loss of $0.34. This compares to loss of $0.33 per share a year ago. zacks.com - 3 months ago
Lyra Therapeutics Reports Second Quarter 2024 Financial Results and Provides Corporate Update – Primary focus continues to be on upcoming results from ENLIGHTEN 1 Phase 3 extension study in 4Q 2024 and ENLIGHTEN 2 pivotal Phase 3 trial in CRS patients in 1H 2025, as planned – globenewswire.com - 3 months ago
Lyra Therapeutics Announces Cost-Cutting Measures to Preserve Capital WATERTOWN, Mass., May 21, 2024 (GLOBE NEWSWIRE) -- Lyra Therapeutics, Inc. (Nasdaq: LYRA) (“Lyra” or the “Company”), today announced that it is advancing its goal to preserve capital by implementing a layoff of approximately 75% of its workforce, in addition to other cost-cutting measures. globenewswire.com - 5 months ago
Why Is Lyra Therapeutics (LYRA) Stock Down 90% Today? Lyra Therapeutics (NASDAQ: LYRA ) stock is falling hard on Monday after the clinical-stage biotechnology company announced results from a Phase 3 clinical trial of LYR-210. LYR-210 is the company's potential treatment for chronic rhinosinusitis currently in development. investorplace.com - 6 months ago
Lyra Therapeutics Reports Topline Results from Phase 3 ENLIGHTEN 1 Trial for LYR-210 in Chronic Rhinosinusitis ENLIGHTEN 1 trial did not meet its primary endpoint Company plans to evaluate full dataset and path forward WATERTOWN, Mass., May 06, 2024 (GLOBE NEWSWIRE) -- Lyra Therapeutics, Inc. (Nasdaq: LYRA) (“Lyra” or the “Company”), today announced topline results from the Company's Phase 3 ENLIGHTEN 1 trial evaluating LYR-210 for the treatment of chronic rhinosinusitis (CRS). globenewswire.com - 6 months ago
Lyra Therapeutics, Inc. (LYRA) Reports Q1 Loss, Tops Revenue Estimates Lyra Therapeutics, Inc. (LYRA) came out with a quarterly loss of $0.35 per share versus the Zacks Consensus Estimate of a loss of $0.26. This compares to loss of $0.44 per share a year ago. zacks.com - 6 months ago
Lyra Therapeutics Reports First Quarter 2024 Financial Results and Provides Corporate Update -- Phase 3 Results from ENLIGHTEN 1 Trial of LYR-210 in Chronic Rhinosinusitis (CRS) Expected in May -- -- Phase 3 Results from ENLIGHTEN 1 Trial of LYR-210 in Chronic Rhinosinusitis (CRS) Expected in May -- globenewswire.com - 6 months ago
3 'Buy-Rated' Biotech Stocks Under $10 Today, we look at three small-cap biotech/biopharma stocks. All three have attractive risk/reward profiles and potential catalysts on the horizon. An investment synopsis on all three firms is presented in the paragraphs below. seekingalpha.com - 6 months ago
8. Profile Summary

Lyra Therapeutics, Inc. LYRA

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COUNTRY US
INDUSTRY Biotechnology
MARKET CAP $ 11.1 M
Dividend Yield 0.00%
Description Lyra Therapeutics, Inc., a clinical-stage therapeutics company, focuses on the development and commercialization of novel integrated drug and delivery solutions for the localized treatment of patients with ear, nose, and throat diseases. It's XTreo technology platform is designed to deliver medicines directly to the affected tissue for sustained periods with a single administration. The company's product candidates include LYR-210, an anti-inflammatory implantable drug matrix for the treatment of chronic rhinosinusitis (CRS), which is in Phase II clinical trial; and LYR-220 for CRS patients with and without nasal polyps. The company was formerly known as 480 Biomedical, Inc. and changed its name to Lyra Therapeutics, Inc. in July 2018. Lyra Therapeutics, Inc. was incorporated in 2005 and is headquartered in Watertown, Massachusetts.
Contact 480 Arsenal Way, Watertown, MA, 02472 https://lyratherapeutics.com
IPO Date May 1, 2020
Employees 88
Officers Mr. Ronan P. O'Brien J.D. Chief Legal Officer Ms. Gloria Cosgrove Senior Vice President of Quality Ms. Allison Nance Senior Vice President of Regulatory Affairs Mr. Ray Knox Vice President of Operations Ms. Vineeta Belanger Ph.D. Senior Vice President of Clinical Affairs Dr. Robert Richard Ph.D. Senior Vice President of Technical Operations Dr. Robert Kern M.D. Chief Clinical Advisor Dr. Harlan W. Waksal M.D. Executive Chairman Mr. Jason Cavalier Chief Financial Officer, Treasurer & Secretary Dr. Maria Palasis Ph.D. Chief Executive Officer, President & Director