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Healthcare - Biotechnology - NASDAQ - US
$ 34.17
-9.34 %
$ 1.89 B
Market Cap
-15.05
P/E
1. INTRINSIC VALUE

Structure Therapeutics Inc., a clinical stage global biopharmaceutical company, develops and delivers novel oral therapeutics to treat a range of chronic diseases with unmet medical needs. Its lead product candidate is GSBR-1290, an oral and biased small molecule agonist of glucagon-like-peptide-1 receptor, a validated G-protein-coupled receptors (GPCRs) drug target for type-2 diabetes mellitus and obesity. The company is also developing oral small molecule therapeutics targeting other GPCRs for the treatment of pulmonary and cardiovascular diseases, including ANPA-0073, a biased agonist, targeting apelin receptor, a GPCR that has been implicated in idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension; and LTSE-2578, an investigational oral small molecule lysophosphatidic acid 1 receptor antagonist for the treatment of IPF.[ Read More ]

The intrinsic value of one GPCR stock under the base case scenario is HIDDEN Compared to the current market price of 34.2 USD, Structure Therapeutics Inc. is HIDDEN

2. FUNDAMENTAL ANALYSIS

Price Chart GPCR

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FINANCIALS
0 REVENUE
0.00%
-103 M OPERATING INCOME
-95.53%
-89.6 M NET INCOME
-74.63%
-79.5 M OPERATING CASH FLOW
-72.35%
-268 M INVESTING CASH FLOW
-332.06%
452 M FINANCING CASH FLOW
1456.25%
0 REVENUE
0.00%
-45.8 M OPERATING INCOME
-37.58%
-34 M NET INCOME
-30.67%
-19.8 M OPERATING CASH FLOW
25.16%
-189 M INVESTING CASH FLOW
7.57%
-63.5 K FINANCING CASH FLOW
-0.01%
Balance Sheet Decomposition Structure Therapeutics Inc.
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Current Assets 474 M
Cash & Short-Term Investments 467 M
Receivables 0
Other Current Assets 6.28 M
Non-Current Assets 8.41 M
Long-Term Investments 0
PP&E 8.36 M
Other Non-Current Assets 45 K
Current Liabilities 24.7 M
Accounts Payable 4.74 M
Short-Term Debt 2.88 M
Other Current Liabilities 17.1 M
Non-Current Liabilities 4.31 M
Long-Term Debt 4.01 M
Other Non-Current Liabilities 298 K
EFFICIENCY
Earnings Waterfall Structure Therapeutics Inc.
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Revenue 0
Cost Of Revenue 949 K
Gross Profit -949 K
Operating Expenses 103 M
Operating Income -103 M
Other Expenses -13.2 M
Net Income -89.6 M
RATIOS
0.00% GROSS MARGIN
0.00%
0.00% OPERATING MARGIN
0.00%
0.00% NET MARGIN
0.00%
-19.79% ROE
-19.79%
-18.59% ROA
-18.59%
-22.68% ROIC
-22.68%
FREE CASH FLOW ANALYSIS
Free Cash Flow Analysis Structure Therapeutics Inc.
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Net Income -89.6 M
Depreciation & Amortization 295 K
Capital Expenditures -2.17 M
Stock-Based Compensation 8.19 M
Change in Working Capital 6.97 M
Others 2.51 M
Free Cash Flow -81.7 M
3. WALL STREET ANALYSTS ESTIMATES
Wall Street Analysts Price Targets Structure Therapeutics Inc.
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Wall Street analysts predict an average 1-year price target for GPCR of $92.4 , with forecasts ranging from a low of $65 to a high of $118 .
GPCR Lowest Price Target Wall Street Target
65 USD 90.23%
GPCR Average Price Target Wall Street Target
92.4 USD 170.41%
GPCR Highest Price Target Wall Street Target
118 USD 245.33%
4. DIVIDEND ANALYSIS
0.00% DIVIDEND YIELD
0 USD DIVIDEND PER SHARE
5. COMPETITION
6. Ownership
Insider Ownership Structure Therapeutics Inc.
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Sold
0-3 MONTHS
0 USD 0
3-6 MONTHS
0 USD 2
6-9 MONTHS
0 USD 1
9-12 MONTHS
0 USD 1
Bought
0 USD 0
0-3 MONTHS
0 USD 0
3-6 MONTHS
0 USD 0
6-9 MONTHS
0 USD 0
9-12 MONTHS
Date Value Insider Amount Avg Price
5 months ago
Jun 10, 2024
Sell 0 USD
Stevens Raymond C
CHIEF EXECUTIVE OFFICER
- 185000
0 USD
5 months ago
Jun 03, 2024
Sell 0 USD
Lin Xichen
CHIEF SCIENTIFIC OFFICER
- 17700
0 USD
5 months ago
Jun 03, 2024
Sell 0 USD
Lin Xichen
CHIEF SCIENTIFIC OFFICER
- 17700
0 USD
8 months ago
Mar 14, 2024
Sell 0 USD
FMR LLC
10 percent owner, other: See Remark 1
- 21997
0 USD
9 months ago
Feb 13, 2024
Sell 0 USD
FMR LLC
10 percent owner, other: See Remark 1
- 525
0 USD
11 months ago
Dec 05, 2023
Sell 0 USD
FMR LLC
10 percent owner
- 16086
0 USD
11 months ago
Dec 05, 2023
Sell 0 USD
FMR LLC
10 percent owner
- 1368
0 USD
1 year ago
Oct 18, 2023
Sell 0 USD
FMR LLC
10 percent owner
- 16086
0 USD
1 year ago
Oct 18, 2023
Sell 0 USD
FMR LLC
10 percent owner
- 1368
0 USD
1 year ago
Feb 07, 2023
Bought 0 USD
Farid Ramy
Director
+ 275000
0 USD
7. News
Structure Therapeutics to Participate in the Jefferies London Healthcare Conference SAN FRANCISCO, Nov. 15, 2024 (GLOBE NEWSWIRE) -- Structure Therapeutics Inc. (NASDAQ: GPCR), a clinical-stage global biopharmaceutical company developing novel oral small molecule therapeutics for metabolic and cardiopulmonary diseases, today announced that management will participate in a presentation and fireside chat, and host one-on-one meetings at the Jefferies London Healthcare Conference being held November 19-21, 2024, in London, UK. globenewswire.com - 1 day ago
Structure Therapeutics Announces First Patients Dosed in Phase 2b ACCESS Clinical Study Evaluating Oral Small Molecule GLP-1 Receptor Agonist, GSBR-1290, for Obesity Phase 2b ACCESS study designed to evaluate multiple doses up to 120 mg of GSBR-1290  over 36 weeks Comprehensive development program also includes Phase 2 ACCESS II study  to evaluate even higher doses of GSBR-1290 over 36 weeks;  first patient expected to be dosed by end of 2024 Topline data from both ACCESS and ACCESS II studies expected in the fourth quarter of 2025 Company to host conference call today at 4:30 p.m. Eastern Time SAN FRANCISCO, Nov. 13, 2024 (GLOBE NEWSWIRE) -- Structure Therapeutics Inc. (NASDAQ: GPCR), a clinical-stage global biopharmaceutical company developing novel oral small molecule therapeutics for metabolic and pulmonary diseases, today announced the first patients have been dosed in the randomized, double-blind, placebo-controlled Phase 2b ACCESS clinical study evaluating GSBR-1290 in participants living with obesity, or overweight with a weight-related comorbidity. globenewswire.com - 3 days ago
Nxera Pharma and Antiverse Enter Collaboration To Design Novel GPCR-Targeted Antibody Therapeutics Using Generative AI Tokyo, Japan and London and Cardiff, UK, 5 November 2024 – Nxera Pharma (“Nxera”; TSE 4565) – formerly known as Sosei Group or Sosei Heptares – and Antiverse, a techbio company designing antibodies for challenging targets, have today announced a multi-target partnership and licensing agreement to design antibodies for G-protein coupled receptors (GPCRs). globenewswire.com - 1 week ago
Best Momentum Stocks to Buy for October 23rd GPCR, RUSHA and NTRA made it to the Zacks Rank #1 (Strong Buy) momentum stocks list on October 23, 2024. zacks.com - 3 weeks ago
Structure Therapeutics: Potential To Have Best-In-Class GLP-1 Agonist For Obesity Patients Positive 12-week data from phase 2a study of GSBR-1290 targeting obesity patients; significant placebo adjusted mean weight loss of 6.2% & 6.9% achieved for capsule and tablet respectively. One analyst believes that the market for obesity treatments could expand to $200 billion by 2031. The 36-week phase 2b study, using GSBR-1290 for the treatment of patients with obesity, expected to start in Q4 of 2024. seekingalpha.com - 3 weeks ago
Does Structure Therapeutics Inc. Sponsored ADR (GPCR) Have the Potential to Rally 115.8% as Wall Street Analysts Expect? The consensus price target hints at an 115.8% upside potential for Structure Therapeutics Inc. Sponsored ADR (GPCR). While empirical research shows that this sought-after metric is hardly effective, an upward trend in earnings estimate revisions could mean that the stock will witness an upside in the near term. zacks.com - 1 month ago
Structure Therapeutics Strengthens Executive Team with Promotion of Blai Coll, M.D., Ph.D. to Chief Medical Officer and Appointment of Ashley Hall, J.D. SAN FRANCISCO, Sept. 17, 2024 (GLOBE NEWSWIRE) -- Structure Therapeutics Inc. (NASDAQ: GPCR), a clinical-stage global biopharmaceutical company developing novel oral small molecule therapeutics for metabolic and cardiopulmonary diseases, today announced key leadership appointments to drive its next phase of development and operational success. Blai Coll, M.D., Ph.D., has been promoted to Chief Medical Officer, replacing Mark Bach, M.D., Ph.D. as part of a planned succession, effective September 18. Dr. Coll has served as Vice President of Clinical Development at Structure since 2022, leading the GSBR-1290 program, Structure's oral small molecule GLP-1 agonist that is planned to enter Phase 2b clinical development for obesity in the fourth quarter of 2024. In addition, Ashley Hall, J.D., has been appointed to the newly created position of Chief Development Officer, and will be responsible for clinical development operations, project management, regulatory affairs and quality assurance. globenewswire.com - 1 month ago
Five Top Obesity Stocks to Buy and Hold Long Term Karl-Hendrik Tittel / Getty Images There's also Altimmune (NASDAQ:ALT), whose pemvidutide treatment led to weight loss while preserving lean mass. 247wallst.com - 2 months ago
Structure Therapeutics Appoints Angus C. Russell to Board of Directors Former Shire CEO brings more than 30 years of experience in building and scaling companies in the global biopharmaceutical industry Former Shire CEO brings more than 30 years of experience in building and scaling companies in the global biopharmaceutical industry globenewswire.com - 2 months ago
Structure Therapeutics Announces Participation in Upcoming Investor Conferences SAN FRANCISCO, Aug. 26, 2024 (GLOBE NEWSWIRE) -- Structure Therapeutics Inc. (NASDAQ: GPCR), a clinical-stage global biopharmaceutical company developing novel oral small molecule therapeutics for metabolic and cardiopulmonary diseases, today announced management will participate at the following investor conferences in September: globenewswire.com - 2 months ago
Obesity drugs' next wave: These companies could snag 20% of GLP-1 market, analysts say While Eli Lilly & Co. and Novo Nordisk dominate the obesity-drug market, there's a vast field of would-be competitors closing in behind them — and the most successful among those next-wave contenders stand to capture up to 20% of the lucrative market, Jefferies analysts said in a research note Monday. marketwatch.com - 2 months ago
3 Promising Biotech Stocks for the Long-Term: August 2024 Some of the best biotech opportunities can be found in oversold obesity treatment stocks. Look at Eli Lilly (NYSE: LLY ), for example. investorplace.com - 3 months ago
8. Profile Summary

Structure Therapeutics Inc. GPCR

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COUNTRY US
INDUSTRY Biotechnology
MARKET CAP $ 1.89 B
Dividend Yield 0.00%
Description Structure Therapeutics Inc., a clinical stage global biopharmaceutical company, develops and delivers novel oral therapeutics to treat a range of chronic diseases with unmet medical needs. Its lead product candidate is GSBR-1290, an oral and biased small molecule agonist of glucagon-like-peptide-1 receptor, a validated G-protein-coupled receptors (GPCRs) drug target for type-2 diabetes mellitus and obesity. The company is also developing oral small molecule therapeutics targeting other GPCRs for the treatment of pulmonary and cardiovascular diseases, including ANPA-0073, a biased agonist, targeting apelin receptor, a GPCR that has been implicated in idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension; and LTSE-2578, an investigational oral small molecule lysophosphatidic acid 1 receptor antagonist for the treatment of IPF. The company was formerly known as ShouTi Inc. Structure Therapeutics Inc. was founded in 2016 and is headquartered in South San Francisco, California.
Contact 611 Gateway Boulevard, South San Francisco, CA, 94080 https://structuretx.com
IPO Date Feb. 3, 2023
Employees 136
Officers Mr. Tony Peng Senior Vice President of Legal Dr. Xichen Lin Ph.D. Chief Scientific Officer Ms. Lani Ibarra Senior Vice President of Clinical Development Operations Mr. Bob Gatmaitan Senior Vice President of People Dr. Hui Lei Ph.D. Senior Vice President of Chemistry Dr. Yingli Ma Ph.D. Chief Technology Officer Dr. Fang Zhang Ph.D. Executive Vice President & Head of Biology Dr. Raymond C. Stevens Ph.D. Chief Executive Officer & Director Mr. Jun S. Yoon Co- Founder, Chief Financial Officer & Secretary Dr. Xinglong Jiang Ph.D. Senior Vice President of Preclinical Development