Nuvation Bio Inc.

Nuvation Bio Inc.

NUVBยทNYSE

$4.72

-4.8%
HealthcareBiotechnology

Nuvation Bio Inc., a clinical-stage biopharmaceutical company, focuses on the development of therapeutic candidates for oncology. The company's lead product candidate is NUV-422, a small molecule inhibitor targeting cyclin-dependent kinase (CDK)2, CDK4, and CDK6. It is also developing NUV-868, a selective oral small molecule BET inhibitor that epigenetically regulates proteins that control tumor growth and differentiation; NUV-569, a differentiated oral small molecule selective inhibitor of the Wee1 kinase for DNA damage repair; NUV-1182, an adenosine receptor inhibitor; and drug-drug conjugate (DDC) platform that focuses on targeting an inhibitor of poly ADP ribose polymerase (PARP) to anti-cancer warheads of existing drugs, as well as PARP inhibitor to address ER+ breast and ovarian cancer. The company was formerly known as RePharmation Inc. and changed its name to Nuvation Bio Inc. in April 2019. Nuvation Bio Inc. was founded in 2018 and is headquartered in New York, New York.

At a Glance

Live Snapshot
Market Cap$1.64B
EPS-0.6000
P/E Ratio-7.87
Earnings Date08/06/2026
3Y-
5Y-
10Y-
3Y+96.0%
5Y+391.0%
10Y+20528.0%
3Y+80.0%
5Y+375.0%
10Y+28054.0%
Nuvation Bio Inc.

Nuvation Bio Inc. Profit Bridge

NUVB ยท NYSE
Revenue62.90M
Cost of Goods Sold (8.44M)
Gross Profit54.46M
Operating Expenses (267.52M)
Operating Income-213.06M
Interest Expense (13.68M)
Other Income/Expense8.44M
Pretax Income-204.63M
Income Tax (0.00)
Net Income-204.63M
Net Income
-204.63M

Profitability Analysis

Gross Margin

86.6%

Exceptional pricing power and cost management. The company retains over half of revenue after direct costs.

Operating Margin

-338.7%

Operating losses indicate the core business is unprofitable. Requires restructuring or revenue growth.

Net Profit Margin

-325.3%

Net losses indicate the company is burning cash. Sustainability depends on path to profitability.

Profitability Insight

Margin squeeze alert: Healthy gross margins but weak operating margins suggest excessive operating expenses. Cost optimization could unlock significant value.

Nuvation Bio Inc. Income Statement

NUVB โ€ข NYSE

Nuvation Bio Inc. Income StatementDec 2025Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020Dec 2019Dec 2018
REVENUE
62.9M
7.9M
0.0
0.0
0.0
0.0
0.0
0.0
GROSS PROFIT
(8.4M)
(7.1M)
(0.0)
(0.0)
(0.0)
(103K)
(0.0)
(0.0)
54.5M
795K
0.0
0.0
0.0
-103K
0.0
0.0
OPERATING INCOME
(267.5M)
(593.4M)
(99.8M)
(119.7M)
(93.3M)
(43.4M)
(32.1M)
(992K)
(151.6M)
(69.2M)
(28.5M)
(31.9M)
(24.3M)
(10.8M)
(7M)
(509.3K)
(115.1M)
(524.2M)
(71.3M)
(87.8M)
(69M)
(32.6M)
(25.1M)
(482.7K)
-213.1M
-592.6M
-99.8M
-119.7M
-93.3M
-43.6M
-32.1M
-992K
PRE-TAX INCOME
(13.7M)
(341K)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
7.7M
26.7M
24.6M
7.4M
3M
1.9M
1.4K
0.0
(856K)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
-1.0
(0.0)
8.4M
24.7M
24M
15.5M
6.5M
1.9M
-1.5M
0.0
-204.6M
-567.9M
-75.8M
-104.2M
-86.8M
-41.7M
-33.6M
-992K
NET INCOME
-204.6M
-567.9M
-75.8M
-104.2M
-86.8M
-41.7M
-33.6M
-992K

SEC Filings

NUVB - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
8-K

8-K 2026

N/A

May 27, 2026
May 21, 2026
2026
8-K

8-K 2026

N/A

May 04, 2026
May 04, 2026
2026
10-Q

10-Q 2026 Q1

Q1

May 04, 2026
March 31, 2026
2026
DEF 14A

DEF 14A 2026

N/A

April 10, 2026
May 21, 2026
2026
10-K

10-K 2025 FY

FY

March 02, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

March 02, 2026
March 02, 2026
2026
8-K

8-K 2026

N/A

January 12, 2026
January 11, 2026
2026
8-K

8-K 2025

N/A

November 26, 2025
November 26, 2025
2025
8-K

8-K 2025

N/A

November 17, 2025
November 17, 2025
2025
10-Q

10-Q 2025 Q3

Q3

November 03, 2025
September 30, 2025
2025
Showing 1 to 10 of 98 filings