Nuvation Bio Inc.

Nuvation Bio Inc.

NUVB·NYSE

$4.72

-4.8%
HealthcareBiotechnology

Nuvation Bio Inc., a clinical-stage biopharmaceutical company, focuses on the development of therapeutic candidates for oncology. The company's lead product candidate is NUV-422, a small molecule inhibitor targeting cyclin-dependent kinase (CDK)2, CDK4, and CDK6. It is also developing NUV-868, a selective oral small molecule BET inhibitor that epigenetically regulates proteins that control tumor growth and differentiation; NUV-569, a differentiated oral small molecule selective inhibitor of the Wee1 kinase for DNA damage repair; NUV-1182, an adenosine receptor inhibitor; and drug-drug conjugate (DDC) platform that focuses on targeting an inhibitor of poly ADP ribose polymerase (PARP) to anti-cancer warheads of existing drugs, as well as PARP inhibitor to address ER+ breast and ovarian cancer. The company was formerly known as RePharmation Inc. and changed its name to Nuvation Bio Inc. in April 2019. Nuvation Bio Inc. was founded in 2018 and is headquartered in New York, New York.

At a Glance

Live Snapshot
Market Cap$1.64B
EPS-0.6000
P/E Ratio-7.87
Earnings Date08/06/2026
nuvb

Nuvation Bio Inc. Street Expectations Map

NUVB · NYSE

Wall Street analysts project that NUVB stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 13.00, with estimates ranging from a low of 10.00 to a high of 17.00.

Lowest Target
10.00
111.86%
Consensus Target
13.00
175.42%
Highest Target
17.00
260.17%

The consensus 1-year price target stands at 13.00, with estimates ranging from a low of 10.00 to a high of 17.00.

Analyst Consensus Analysis

Upside Potential

+175.4%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

53.8% spread

Mixed analyst views. Wide target range suggests differing opinions on key value drivers, growth prospects, or risk factors.

Analyst Conviction

Low

Bearish or uncertain outlook. Limited upside or poor consensus suggests challenges ahead or fundamental concerns.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

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Nuvation Bio Inc. Forward Estimates of Revenue

NUVB · NYSE
Latest Revenue
62.90M
FY 2025
Avg Estimate
202.35M
FY 2026
Estimate Range
193.70M - 215.33M
Analyst Spread

Forward Growth Analysis

Projected Growth+221.7%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage7 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread11%

Reasonable estimate spread indicates general agreement with normal forecast variance.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

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Nuvation Bio Inc. Forward Estimates of Net Income

NUVB · NYSE
Latest Net Income
-204.63M
FY 2025
Avg Estimate
-116.79M
FY 2026
Estimate Range
-265.40M - -62.56M
Analyst Spread

Forward Growth Analysis

Projected Growth+42.9%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage7 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread174%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomes—suggests elevated risk and potential volatility.

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Nuvation Bio Inc. Forward Estimates of EPS

NUVB · NYSE
Latest EPS
-0.60
FY 2025
Avg Estimate
$-0.36
FY 2026
Estimate Range
$-0.78 - $-0.18
Analyst Spread

Forward Growth Analysis

Projected Growth+40.8%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage5 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread167%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomes—suggests elevated risk and potential volatility.

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Nuvation Bio Inc. Forward Estimates of EBIT

NUVB · NYSE
Latest EBIT
-190.94M
FY 2025
Avg Estimate
40.47M
FY 2026
Estimate Range
38.74M - 43.07M
Analyst Spread

Forward Growth Analysis

Projected Growth+121.2%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage7 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread11%

Reasonable estimate spread indicates general agreement with normal forecast variance.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

nuvb

Nuvation Bio Inc. Forward Estimates of EBITDA

NUVB · NYSE
Latest EBITDA
-190.94M
FY 2025
Avg Estimate
40.47M
FY 2026
Estimate Range
38.74M - 43.07M
Analyst Spread

Forward Growth Analysis

Projected Growth+121.2%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage7 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread11%

Reasonable estimate spread indicates general agreement with normal forecast variance.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

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Nuvation Bio Inc. Forward Estimates of SG&A Expense

NUVB · NYSE
Latest SG&A Expense
151.56M
FY 2025
Avg Estimate
574.82M
FY 2026
Estimate Range
550.24M - 611.66M
Analyst Spread

Forward Growth Analysis

Projected Growth+279.3%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage7 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread11%

Reasonable estimate spread indicates general agreement with normal forecast variance.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

nuvb

Nuvation Bio Inc. Insider Positioning

NUVB · NYSE

During the last 12 months, insiders have purchased $1.06M and sold $7.05M worth of NUVB shares, resulting in $5.99M of net selling activity.

3 Months

Bought

0

0.00

Sold

286.8K

1.34M

Net Activity

-1.3M

-$1.34M

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

0

0.00

Sold

820.0K

5.71M

Net Activity

-5.7M

-$5.71M

9-12 Months

Bought

593.3K

1.06M

Sold

0

0.00

Net Activity

+1.1M

+$1.06M

Top Buyers

1
HD

Hung David

Director, 10 Percent Owner, Officer: President And Ceo

500.0K shares1 transactions

$894K

2
SC

Sjogren Colleen

Officer: Chief Commercial Officer

50.0K shares1 transactions

$90K

3
WK

Wentworth Kerry

Officer: Chief Regulatory Officer

26.0K shares1 transactions

$47K

4
MS

Markel Stacy

Officer: Chief People Officer

10.0K shares1 transactions

$17K

5
SP

Sauvage Philippe

Officer: Chief Financial Officer

7.3K shares2 transactions

$13K

Top Sellers

1
HG

Hattersley Gary

Officer: Chief Scientific Officer

400.0K shares2 transactions

$2.67M

2
LD

Liu Dongfang

Officer: Chief Medical Officer

270.0K shares7 transactions

$1.87M

3
HDC

Hanley David C.

Officer: Chief Technical Operations

200.0K shares1 transactions

$1.43M

4
WK

Wentworth Kerry

Officer: Chief Regulatory Officer

236.8K shares2 transactions

$1.09M

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $5.99M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.15:1

Weak buy/sell ratio. Selling significantly exceeds buying—monitor for potential fundamental concerns.

Recent Trend (3 Months)

$1.34M

Heavy recent selling activity. Recent insider sales notably exceed purchases—may warrant investigation into company developments.

Insider Participation

Moderate Buying

5 insider buyers vs. 4 sellers. More insiders buying than selling indicates positive sentiment.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.