Tyra Biosciences, Inc.

Tyra Biosciences, Inc.

TYRA·NASDAQ

$26.60

-7.3%
HealthcareBiotechnology

Tyra Biosciences, Inc., a preclinical-stage biopharmaceutical company, focuses on developing therapies to overcome tumor resistance and enhance outcomes for patients with cancer. Its lead product candidate is TYRA-300, a selective inhibitor of fibroblast growth factor receptor (FGFR)3 for the treatment of muscle invasive bladder cancer. The company is also developing programs targeting FGFR2- intrahepatic cholangiocarcinoma,FGFR3-related achondroplasia, REarranged during transfection kinase, and FGFR4-related cancers. In addition, the company offers SNAP platform which enable rapid structural design through iterative molecular SNAPshots. Tyra Biosciences, Inc. was incorporated in 2018 and is based in Carlsbad, California.

At a Glance

Live Snapshot
Market Cap$1.58B
EPS-2.0100
P/E Ratio-13.23
Earnings Date08/06/2026
-50.10%
Return on Invested Capital
68%
3Y+122.0%
5Y-23.0%
10Y-172.0%
-46.28%
Return on Equity
84%
3Y+116.0%
5Y-168.0%
10Y-154.0%
-42.44%
Return on Assets
78%
3Y+104.0%
5Y-27.0%
10Y-94.0%
Tyra Biosciences, Inc.

Tyra Biosciences, Inc. Management Team

TYRA · NASDAQ
DP

Dr. Piyush R. Patel Ph.D.

Chief Development Officer

Born 1965(Age 61)
DD

Dr. Douglas Warner M.D.

Chief Medical Officer

Compensation

$627,900

Born 1972(Age 54)
DR

Dr. Ronald V. Swanson Ph.D.

Chief Scientific Officer

Compensation

$536,188

Born 1963(Age 63)
DR

Dr. Robert L. Hudkins Ph.D.

Chief Technology Officer

Born 1955(Age 71)
MD

Mr. Daniel Bensen

Co-Founder & Chief Operating Officer

Compensation

$737,643

Born 1975(Age 51)
male
DT

Dr. Todd Harris Ph.D.

Co-Founder, President, Chief Executive Officer, Secretary, Treasurer & Director

Compensation

$1,067,050

Born 1979(Age 47)
MA

Mr. Ali D. Fawaz J.D.

General Counsel

Compensation

$629,230

male
ME

Mr. Erik Goluboff

Senior Vice President of Clinical Development

male
MS

Ms. Sarah Honig

Senior Vice President of Corporate Development & Strategy

female
LP

Liz Pagano

Senior Vice President of Human Resources

tyra

Tyra Biosciences, Inc. Insider Positioning

TYRA · NASDAQ

During the last 12 months, insiders have purchased $27.26M and sold $10.97M worth of TYRA shares, resulting in $16.29M of net buying activity.

3 Months

Bought

0

0.00

Sold

14.3K

528.51K

Net Activity

-529K

-$529K

3-6 Months

Bought

0

0.00

Sold

27.1K

696.80K

Net Activity

-697K

-$697K

6-9 Months

Bought

701

6.40K

Sold

502.4K

9.11M

Net Activity

-9.1M

-$9.11M

9-12 Months

Bought

2.7M

27.25M

Sold

61.4K

628.26K

Net Activity

+26.6M

+$26.62M

Top Buyers

1
RCML

Ra Capital Management, L.P.

Director, 10 Percent Owner:

1.6M shares6 transactions

$15.32M

2
HT

Harris Todd

Director, Officer: President And Ceo

570.0K shares1 transactions

$6.13M

3
WDJ

Warner Douglas J

Officer: Chief Medical Officer

200.0K shares1 transactions

$2.15M

4
FA

Fuhrman Alan

Officer: Chief Financial Officer

170.7K shares2 transactions

$1.83M

5
BD

Bensen Daniel

Officer: Chief Operating Officer

170.0K shares1 transactions

$1.83M

Top Sellers

1
MRJ

More Robert J

Director

256.9K shares2 transactions

$5.25M

2
BD

Bensen Daniel

Officer: Chief Discovery Officer

272.6K shares8 transactions

$4.56M

3
KG

Kaplan Gilla

Director

75.7K shares6 transactions

$1.16M

Insider Activity Analysis

Net Insider Sentiment

Bullish

Positive insider sentiment with $16.29M net buying. Buying activity substantially exceeds selling, indicating insider confidence.

Buy/Sell Ratio

2.49:1

Strong buy/sell ratio. Buying is at least double the selling activity, suggesting robust insider confidence.

Recent Trend (3 Months)

$529K

Heavy recent selling activity. Recent insider sales notably exceed purchases—may warrant investigation into company developments.

Insider Participation

Moderate Buying

5 insider buyers vs. 3 sellers. More insiders buying than selling indicates positive sentiment.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.

SEC Filings

TYRA - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 17, 2026
May 28, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 18, 2025
May 29, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 18, 2024
May 29, 2024
2024
DEF 14A

DEF 14A 2023

N/A

April 17, 2023
May 31, 2023
2023
DEF 14A

DEF 14A 2022

N/A

April 28, 2022
June 13, 2022
2022
Showing 1 to 5 of 5 filings