Entrada Therapeutics, Inc.

Entrada Therapeutics, Inc.

TRDA·NASDAQ

$6.58

-0.90%
HealthcareBiotechnology

Entrada Therapeutics, Inc., a biotechnology company, develops endosomal escape vehicle (EEV) therapeutics for the treatment of multiple neuromuscular diseases. Its endosomal escape vehicle platform develops a portfolio of oligonucleotide, antibody, and enzyme-based programs. The company's lead product candidate is ENTR-601-44, which is in preclinical trail for the treatment of Duchenne muscular dystrophy and myotonic dystrophy type 1. It also engages in the development of EEV-PMO-CAG for the treatment of myotonic dystrophy type 1. The company was formerly known as CycloPorters, Inc. and changed its name to Entrada Therapeutics, Inc. in October 2017. Entrada Therapeutics, Inc. was incorporated in 2016 and is headquartered in Boston, Massachusetts.

At a Glance

Live Snapshot
Market Cap$255.44M
EPS-3.4700
P/E Ratio-1.90
Earnings Date08/05/2026
-43.69%
Return on Invested Capital
-565%
3Y+7.0%
5Y-34.0%
10Y-34.0%
-46.96%
Return on Equity
-407%
3Y+5.0%
5Y-173.0%
10Y-257.0%
-38.09%
Return on Assets
-405%
3Y+1.0%
5Y-37.0%
10Y+49.0%
Entrada Therapeutics, Inc.

Entrada Therapeutics, Inc. Management Team

TRDA · NASDAQ
MK

Ms. Karla MacDonald

Chief Corporate Affairs Officer

female
MD

Mr. Dipal Doshi

Chief Executive Officer & Director

Compensation

$959,310

Born 1976(Age 50)
male
MK

Mr. Kory James Wentworth CPA

Chief Financial Officer & Treasurer

Born 1979(Age 47)
male
ML

Mr. Leo Qian Ph.D.

Co-Founder & Vice President of Discovery Research

male
DJ

Dr. Jared Cohen J.D., Ph.D.

General Counsel

MN

Mr. Nathan J. Dowden

President & Chief Operating Officer

Compensation

$709,810

Born 1971(Age 55)
male
DN

Dr. Natarajan Sethuraman Ph.D.

President of Research & Development

Compensation

$727,192

Born 1962(Age 64)
MK

Ms. Kerry Robert M.S.

Senior Vice President of People

female
MK

Mr. Kevin Healy Ph.D.

Senior Vice President of Regulatory Affairs

male
MM

Murali Mallem

Vice President & Head of CMC

trda

Entrada Therapeutics, Inc. Insider Positioning

TRDA · NASDAQ

During the last 12 months, insiders have purchased $990K and sold $5.40M worth of TRDA shares, resulting in $4.41M of net selling activity.

3 Months

Bought

5.0K

29.32K

Sold

74.9K

1.07M

Net Activity

-1.0M

-$1.04M

3-6 Months

Bought

0

0.00

Sold

8.0K

97.89K

Net Activity

-98K

-$98K

6-9 Months

Bought

24.6K

210.12K

Sold

408.9K

3.61M

Net Activity

-3.4M

-$3.40M

9-12 Months

Bought

95.0K

750.50K

Sold

92.1K

625.10K

Net Activity

+125K

+$125K

Top Buyers

1
BBAL

Baker Bros. Advisors Lp

10 Percent Owner

24.6K shares2 transactions

$210K

2
ZBG

Zeiher Bernhardt G

Director

24.0K shares2 transactions

$179K

3
KPS

Kim Peter S

Director

19.0K shares1 transactions

$150K

4
TM

Thistle Mary

Director

19.0K shares1 transactions

$150K

5
CG

Chapman Gina

Director

19.0K shares1 transactions

$150K

Top Sellers

1
PK

Parmar Kush

Director, 10 Percent Owner:

239.0K shares5 transactions

$2.03M

2
5VVL

5Am Ventures V, L.P.

10 Percent Owner

239.0K shares5 transactions

$2.03M

3
WKJ

Wentworth Kory James

Officer: Chief Financial Officer

37.6K shares6 transactions

$443K

4
DNJ

Dowden Nathan J

Officer: President & Coo

31.8K shares4 transactions

$435K

5
SN

Sethuraman Natarajan

Officer: President, Research & Develop.

27.7K shares2 transactions

$408K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $4.41M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.18:1

Weak buy/sell ratio. Selling significantly exceeds buying—monitor for potential fundamental concerns.

Recent Trend (3 Months)

$1.04M

Heavy recent selling activity. Recent insider sales notably exceed purchases—may warrant investigation into company developments.

Insider Participation

Balanced

5 insider buyers and 5 sellers. Equal participation suggests mixed or neutral insider views.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.

SEC Filings

TRDA - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 24, 2026
June 10, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 25, 2025
June 11, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 29, 2024
June 13, 2024
2024
DEF 14A

DEF 14A 2023

N/A

April 25, 2023
June 08, 2023
2023
DEF 14A

DEF 14A 2022

N/A

April 19, 2022
June 02, 2022
2022
Showing 1 to 5 of 5 filings