Entrada Therapeutics, Inc.

Entrada Therapeutics, Inc.

TRDAยทNASDAQ

$6.94

+4.5%
HealthcareBiotechnology

Entrada Therapeutics, Inc., a biotechnology company, develops endosomal escape vehicle (EEV) therapeutics for the treatment of multiple neuromuscular diseases. Its endosomal escape vehicle platform develops a portfolio of oligonucleotide, antibody, and enzyme-based programs. The company's lead product candidate is ENTR-601-44, which is in preclinical trail for the treatment of Duchenne muscular dystrophy and myotonic dystrophy type 1. It also engages in the development of EEV-PMO-CAG for the treatment of myotonic dystrophy type 1. The company was formerly known as CycloPorters, Inc. and changed its name to Entrada Therapeutics, Inc. in October 2017. Entrada Therapeutics, Inc. was incorporated in 2016 and is headquartered in Boston, Massachusetts.

At a Glance

Live Snapshot
Market Cap$269.40M
EPS-3.4700
P/E Ratio-2.00
Earnings Date08/05/2026
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Entrada Therapeutics, Inc. Street Expectations Map

TRDA ยท NASDAQ

Wall Street analysts project that TRDA stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 17.00, with estimates ranging from a low of 10.00 to a high of 21.00.

Lowest Target
10.00
44.10%
Consensus Target
17.00
144.97%
Highest Target
21.00
202.62%

The consensus 1-year price target stands at 17.00, with estimates ranging from a low of 10.00 to a high of 21.00.

Analyst Consensus Analysis

Upside Potential

+145.0%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

64.7% spread

High uncertainty. Very wide target spread indicates significant disagreement among analystsโ€”major valuation uncertainty or transformation underway.

Analyst Conviction

Low

High uncertainty: Wide dispersion indicates analysts struggle to agree on valuationโ€”proceed with caution and independent analysis.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

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Entrada Therapeutics, Inc. Forward Estimates of Revenue

TRDA ยท NASDAQ
Latest Revenue
25.42M
FY 2025
Avg Estimate
20.18M
FY 2026
Estimate Range
14.80M - 25.56M
Analyst Spread

Forward Growth Analysis

Projected Growth-20.6%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread53%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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Entrada Therapeutics, Inc. Forward Estimates of Net Income

TRDA ยท NASDAQ
Latest Net Income
-143.75M
FY 2025
Avg Estimate
-163.21M
FY 2026
Estimate Range
-183.49M - -142.92M
Analyst Spread

Forward Growth Analysis

Projected Growth-13.5%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread25%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

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Entrada Therapeutics, Inc. Forward Estimates of EPS

TRDA ยท NASDAQ
Latest EPS
-3.47
FY 2025
Avg Estimate
$-4.13
FY 2026
Estimate Range
$-4.70 - $-3.66
Analyst Spread

Forward Growth Analysis

Projected Growth-19.1%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread25%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Entrada Therapeutics, Inc. Forward Estimates of EBIT

TRDA ยท NASDAQ
Latest EBIT
-142.83M
FY 2025
Avg Estimate
12.91M
FY 2026
Estimate Range
9.47M - 16.35M
Analyst Spread

Forward Growth Analysis

Projected Growth+109.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread53%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Entrada Therapeutics, Inc. Forward Estimates of EBITDA

TRDA ยท NASDAQ
Latest EBITDA
-142.40M
FY 2025
Avg Estimate
13.07M
FY 2026
Estimate Range
9.59M - 16.55M
Analyst Spread

Forward Growth Analysis

Projected Growth+109.2%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread53%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Entrada Therapeutics, Inc. Forward Estimates of SG&A Expense

TRDA ยท NASDAQ
Latest SG&A Expense
41.05M
FY 2025
Avg Estimate
13.86M
FY 2026
Estimate Range
10.16M - 17.55M
Analyst Spread

Forward Growth Analysis

Projected Growth-66.2%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread53%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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Entrada Therapeutics, Inc. Insider Positioning

TRDA ยท NASDAQ

During the last 12 months, insiders have purchased $990K and sold $5.40M worth of TRDA shares, resulting in $4.41M of net selling activity.

3 Months

Bought

5.0K

29.32K

Sold

74.9K

1.07M

Net Activity

-1.0M

-$1.04M

3-6 Months

Bought

0

0.00

Sold

8.0K

97.89K

Net Activity

-98K

-$98K

6-9 Months

Bought

24.6K

210.12K

Sold

408.9K

3.61M

Net Activity

-3.4M

-$3.40M

9-12 Months

Bought

95.0K

750.50K

Sold

92.1K

625.10K

Net Activity

+125K

+$125K

Top Buyers

1
BBAL

Baker Bros. Advisors Lp

10 Percent Owner

24.6K sharesโ€ข2 transactions

$210K

2
ZBG

Zeiher Bernhardt G

Director

24.0K sharesโ€ข2 transactions

$179K

3
KPS

Kim Peter S

Director

19.0K sharesโ€ข1 transactions

$150K

4
TM

Thistle Mary

Director

19.0K sharesโ€ข1 transactions

$150K

5
CG

Chapman Gina

Director

19.0K sharesโ€ข1 transactions

$150K

Top Sellers

1
PK

Parmar Kush

Director, 10 Percent Owner:

239.0K sharesโ€ข5 transactions

$2.03M

2
5VVL

5Am Ventures V, L.P.

10 Percent Owner

239.0K sharesโ€ข5 transactions

$2.03M

3
WKJ

Wentworth Kory James

Officer: Chief Financial Officer

37.6K sharesโ€ข6 transactions

$443K

4
DNJ

Dowden Nathan J

Officer: President & Coo

31.8K sharesโ€ข4 transactions

$435K

5
SN

Sethuraman Natarajan

Officer: President, Research & Develop.

27.7K sharesโ€ข2 transactions

$408K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $4.41M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.18:1

Weak buy/sell ratio. Selling significantly exceeds buyingโ€”monitor for potential fundamental concerns.

Recent Trend (3 Months)

$1.04M

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

Balanced

5 insider buyers and 5 sellers. Equal participation suggests mixed or neutral insider views.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.