Tango Therapeutics, Inc.

Tango Therapeutics, Inc.

TNGX·NASDAQ

$21.47

-7.1%
HealthcareBiotechnology

Tango Therapeutics, Inc., a biotechnology company, discovers and develops drugs for the treatment of cancer. Its lead program is TNG908, a synthetic lethal small molecule inhibitor of protein arginine methyltransferase 5 that is being developed as a treatment for cancers with methylthioadenosine phosphorylase deletions. The company also develops Ubiquitin-specific protease 1, an inhibitor to treat patients with BRCA1 or BRCA2-mutant cancers; and Target 3 for STK11-mutant cancers. Tango Therapeutics, Inc. has a strategic collaboration with Gilead Sciences, Inc. for the discovery, development, and commercialization of a pipeline of therapies for patients with cancer. The company was founded in 2017 and is based in Cambridge, Massachusetts.

At a Glance

Live Snapshot
Market Cap$2.49B
EPS-0.8700
P/E Ratio-24.68
Earnings Date08/04/2026
-29.31%
Return on Invested Capital
-43%
3Y+1.0%
5Y-6.0%
10Y-41.0%
-29.35%
Return on Equity
-55%
3Y-32.0%
5Y-78.0%
10Y-84.0%
-25.48%
Return on Assets
-38%
3Y+3.0%
5Y+2.0%
10Y+1.0%
Tango Therapeutics, Inc.

Tango Therapeutics, Inc. Management Team

TNGX · NASDAQ
MD

Ms. Daniella Beckman CPA

Chief Financial Officer

Compensation

$717,616

Born 1979(Age 47)
female
MJ

Ms. Julie Carretero

Chief Human Resources Officer

Born 1972(Age 54)
female
MD

Mr. Douglas J. Barry Esq., J.D.

Chief Legal Officer, Chief Compliance Officer & Corporate Secretary

Compensation

$674,222

Born 1970(Age 56)
male
MJ

Mr. Jannik N. Andersen Ph.D.

Chief Scientific Officer

male
DA

Dr. Antoni Ribas M.D., Ph.D.

Founder & Member of Scientific Advisory Board

Born 1967(Age 59)
DW

Dr. William G. Kaelin Jr., M.D.

Founder & Member of Scientific Advisory Board

Born 1958(Age 68)
DM

Dr. Michael Palmieri Ph.D.

Head of Technical Operations

DA

Dr. Adam S. Crystal M.D., Ph.D.

President of Research & Development

Compensation

$882,167

Born 1977(Age 49)
DB

Dr. Barbara L. Weber M.D.

President, Chief Executive Officer & Director

Compensation

$1,125,489

Born 1957(Age 69)
ME

Ms. Elizabeth Pingpank Hickin

Vice President of IR & Corporate Communications

female
tngx

Tango Therapeutics, Inc. Insider Positioning

TNGX · NASDAQ

During the last 12 months, insiders have purchased $1.33M and sold $29.80M worth of TNGX shares, resulting in $28.47M of net selling activity.

3 Months

Bought

0

0.00

Sold

103.4K

2.32M

Net Activity

-2.3M

-$2.32M

3-6 Months

Bought

0

0.00

Sold

84.8K

1.12M

Net Activity

-1.1M

-$1.12M

6-9 Months

Bought

150.0K

1.20M

Sold

1.4M

12.02M

Net Activity

-10.8M

-$10.82M

9-12 Months

Bought

37.5K

131.62K

Sold

2.0M

14.33M

Net Activity

-14.2M

-$14.20M

Top Buyers

1
PM

Peters Malte

Director

187.5K shares2 transactions

$1.33M

Top Sellers

1
TRVIL

Third Rock Ventures Iv, L.P.

10 Percent Owner

3.5M shares7 transactions

$26.35M

2
CA

Crystal Adam

Officer: President, R&D

178.0K shares6 transactions

$3.32M

3
BD

Beckman Daniella

Officer: Chief Financial Officer

10.2K shares1 transactions

$125K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $28.47M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.04:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$2.32M

Heavy recent selling activity. Recent insider sales notably exceed purchases—may warrant investigation into company developments.

Insider Participation

High Selling

3 insider sellers vs. 1 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.

SEC Filings

TNGX - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 17, 2026
April 16, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 21, 2025
April 21, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 29, 2024
December 31, 2024
2024
DEF 14A

DEF 14A 2023

N/A

April 24, 2023
June 06, 2023
2023
DEF 14A

DEF 14A 2022

N/A

April 26, 2022
June 08, 2022
2022
Showing 1 to 5 of 5 filings