Tango Therapeutics, Inc.

Tango Therapeutics, Inc.

TNGXยทNASDAQ

$21.47

-7.1%
HealthcareBiotechnology

Tango Therapeutics, Inc., a biotechnology company, discovers and develops drugs for the treatment of cancer. Its lead program is TNG908, a synthetic lethal small molecule inhibitor of protein arginine methyltransferase 5 that is being developed as a treatment for cancers with methylthioadenosine phosphorylase deletions. The company also develops Ubiquitin-specific protease 1, an inhibitor to treat patients with BRCA1 or BRCA2-mutant cancers; and Target 3 for STK11-mutant cancers. Tango Therapeutics, Inc. has a strategic collaboration with Gilead Sciences, Inc. for the discovery, development, and commercialization of a pipeline of therapies for patients with cancer. The company was founded in 2017 and is based in Cambridge, Massachusetts.

At a Glance

Live Snapshot
Market Cap$2.49B
EPS-0.8700
P/E Ratio-24.68
Earnings Date08/04/2026
tngx

Tango Therapeutics, Inc. Street Expectations Map

TNGX ยท NASDAQ

Wall Street analysts project that TNGX stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 34.83, with estimates ranging from a low of 24.00 to a high of 55.00.

Lowest Target
24.00
11.78%
Consensus Target
34.83
62.23%
Highest Target
55.00
156.17%

The consensus 1-year price target stands at 34.83, with estimates ranging from a low of 24.00 to a high of 55.00.

Analyst Consensus Analysis

Upside Potential

+62.2%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

89.0% spread

High uncertainty. Very wide target spread indicates significant disagreement among analystsโ€”major valuation uncertainty or transformation underway.

Analyst Conviction

Low

High uncertainty: Wide dispersion indicates analysts struggle to agree on valuationโ€”proceed with caution and independent analysis.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

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Tango Therapeutics, Inc. Forward Estimates of Revenue

TNGX ยท NASDAQ
Latest Revenue
62.38M
FY 2025
Avg Estimate
7.49M
FY 2026
Estimate Range
7.43M - 7.93M
Analyst Spread

Forward Growth Analysis

Projected Growth-88.0%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread7%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

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Tango Therapeutics, Inc. Forward Estimates of Net Income

TNGX ยท NASDAQ
Latest Net Income
-101.59M
FY 2025
Avg Estimate
-139.32M
FY 2026
Estimate Range
-158.04M - -120.61M
Analyst Spread

Forward Growth Analysis

Projected Growth-37.1%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread27%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

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Tango Therapeutics, Inc. Forward Estimates of EPS

TNGX ยท NASDAQ
Latest EPS
-0.87
FY 2025
Avg Estimate
$-1.25
FY 2026
Estimate Range
$-1.45 - $-1.10
Analyst Spread

Forward Growth Analysis

Projected Growth-43.3%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage7 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread27%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

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Tango Therapeutics, Inc. Forward Estimates of EBIT

TNGX ยท NASDAQ
Latest EBIT
-111.29M
FY 2025
Avg Estimate
-7.49M
FY 2026
Estimate Range
-7.93M - -7.43M
Analyst Spread

Forward Growth Analysis

Projected Growth+93.3%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread7%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

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Tango Therapeutics, Inc. Forward Estimates of EBITDA

TNGX ยท NASDAQ
Latest EBITDA
-109.01M
FY 2025
Avg Estimate
-7.49M
FY 2026
Estimate Range
-7.93M - -7.43M
Analyst Spread

Forward Growth Analysis

Projected Growth+93.1%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread7%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

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Tango Therapeutics, Inc. Forward Estimates of SG&A Expense

TNGX ยท NASDAQ
Latest SG&A Expense
41.51M
FY 2025
Avg Estimate
7.14M
FY 2026
Estimate Range
7.09M - 7.56M
Analyst Spread

Forward Growth Analysis

Projected Growth-82.8%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread7%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

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Tango Therapeutics, Inc. Insider Positioning

TNGX ยท NASDAQ

During the last 12 months, insiders have purchased $1.33M and sold $29.80M worth of TNGX shares, resulting in $28.47M of net selling activity.

3 Months

Bought

0

0.00

Sold

103.4K

2.32M

Net Activity

-2.3M

-$2.32M

3-6 Months

Bought

0

0.00

Sold

84.8K

1.12M

Net Activity

-1.1M

-$1.12M

6-9 Months

Bought

150.0K

1.20M

Sold

1.4M

12.02M

Net Activity

-10.8M

-$10.82M

9-12 Months

Bought

37.5K

131.62K

Sold

2.0M

14.33M

Net Activity

-14.2M

-$14.20M

Top Buyers

1
PM

Peters Malte

Director

187.5K sharesโ€ข2 transactions

$1.33M

Top Sellers

1
TRVIL

Third Rock Ventures Iv, L.P.

10 Percent Owner

3.5M sharesโ€ข7 transactions

$26.35M

2
CA

Crystal Adam

Officer: President, R&D

178.0K sharesโ€ข6 transactions

$3.32M

3
BD

Beckman Daniella

Officer: Chief Financial Officer

10.2K sharesโ€ข1 transactions

$125K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $28.47M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.04:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$2.32M

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

High Selling

3 insider sellers vs. 1 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.