Sarepta Therapeutics, Inc.

Sarepta Therapeutics, Inc.

SRPTยทNASDAQ

$16.74

+3.1%
HealthcareBiotechnology

Sarepta Therapeutics, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery and development of RNA-targeted therapeutics, gene therapies, and other genetic therapeutic modalities for the treatment of rare diseases. It offers EXONDYS 51 injection to treat duchenne muscular dystrophy (duchenne) in patients with confirmed mutation of the dystrophin gene that is amenable to exon 51 skipping; and VYONDYS 53 for the treatment of duchenne in patients with confirmed mutation of the dystrophin gene that is amenable to exon 53 skipping. The company is also developing AMONDYS 45, a product candidate that uses phosphorodiamidate morpholino oligomer chemistry and exon-skipping technology to skip exon 45 of the dystrophin gene; SRP-5051, a peptide conjugated PMO that binds exon 51 of dystrophin pre-mRNA; SRP-9001, a DMD micro-dystrophin gene therapy program; and SRP-9003, a limb-girdle muscular dystrophies gene therapy program. It has collaboration agreements with F. Hoffman-La Roche Ltd; Nationwide Children's Hospital; Lysogene; Duke University; Genethon; and StrideBio. The company was incorporated in 1980 and is headquartered in Cambridge, Massachusetts.

At a Glance

Live Snapshot
Market Cap$1.77B
EPS-7.1300
P/E Ratio-2.35
Earnings Date08/05/2026
srpt

Sarepta Therapeutics, Inc. Street Expectations Map

SRPT ยท NASDAQ

Wall Street analysts project that SRPT stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 25.14, with estimates ranging from a low of 14.00 to a high of 35.00.

Lowest Target
14.00
-16.35%
Consensus Target
25.14
50.22%
Highest Target
35.00
109.13%

The consensus 1-year price target stands at 25.14, with estimates ranging from a low of 14.00 to a high of 35.00.

Analyst Consensus Analysis

Upside Potential

+50.2%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

83.5% spread

High uncertainty. Very wide target spread indicates significant disagreement among analystsโ€”major valuation uncertainty or transformation underway.

Risk-Reward Profile

6.68x

Favorable risk-reward. Potential upside significantly exceeds downside risk, offering asymmetric return profile attractive for risk-tolerant investors.

Analyst Conviction

Low

High uncertainty: Wide dispersion indicates analysts struggle to agree on valuationโ€”proceed with caution and independent analysis.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

srpt

Sarepta Therapeutics, Inc. Forward Estimates of Revenue

SRPT ยท NASDAQ
Latest Revenue
2.20B
FY 2025
Avg Estimate
1.57B
FY 2026
Estimate Range
1.37B - 1.78B
Analyst Spread

Forward Growth Analysis

Projected Growth-28.5%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage17 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread26%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

srpt

Sarepta Therapeutics, Inc. Forward Estimates of Net Income

SRPT ยท NASDAQ
Latest Net Income
-713.41M
FY 2025
Avg Estimate
253.95M
FY 2026
Estimate Range
115.96M - 303.09M
Analyst Spread

Forward Growth Analysis

Projected Growth+135.6%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage17 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread74%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

srpt

Sarepta Therapeutics, Inc. Forward Estimates of EPS

SRPT ยท NASDAQ
Latest EPS
-7.13
FY 2025
Avg Estimate
$1.84
FY 2026
Estimate Range
$1.07 - $2.81
Analyst Spread

Forward Growth Analysis

Projected Growth+125.8%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage12 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread94%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

srpt

Sarepta Therapeutics, Inc. Forward Estimates of EBIT

SRPT ยท NASDAQ
Latest EBIT
-692.49M
FY 2025
Avg Estimate
-740.97M
FY 2026
Estimate Range
-839.77M - -647.12M
Analyst Spread

Forward Growth Analysis

Projected Growth-7.0%

Declining expectations indicate headwindsโ€”investigate whether temporary or structural issues.

Analyst Coverage17 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread26%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

srpt

Sarepta Therapeutics, Inc. Forward Estimates of EBITDA

SRPT ยท NASDAQ
Latest EBITDA
-647.97M
FY 2025
Avg Estimate
-658.57M
FY 2026
Estimate Range
-746.38M - -575.15M
Analyst Spread

Forward Growth Analysis

Projected Growth-1.6%

Declining expectations indicate headwindsโ€”investigate whether temporary or structural issues.

Analyst Coverage17 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread26%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

srpt

Sarepta Therapeutics, Inc. Forward Estimates of SG&A Expense

SRPT ยท NASDAQ
Latest SG&A Expense
478.94M
FY 2025
Avg Estimate
678.16M
FY 2026
Estimate Range
592.26M - 768.58M
Analyst Spread

Forward Growth Analysis

Projected Growth+41.6%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage17 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread26%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Well-supported growth expectations: Strong analyst coverage combined with positive growth projections provides confidence in forward outlook.

srpt

Sarepta Therapeutics, Inc. Insider Positioning

SRPT ยท NASDAQ

During the last 12 months, insiders have sold $417K worth of SRPT shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

7.2K

123.21K

Net Activity

-123K

-$123K

3-6 Months

Bought

0

0.00

Sold

13.2K

294.20K

Net Activity

-294K

-$294K

6-9 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

No buying activity

Top Sellers

1
EIM

Estepan Ian Michael

Officer: Chief Operating Officer

13.2K sharesโ€ข1 transactions

$294K

2
MS

Mayo Stephen

Director

7.2K sharesโ€ข1 transactions

$123K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $417K net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$123K

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

High Selling

2 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Persistent selling pressure: Consistent insider selling with weak buy/sell ratio suggests insiders may be capitalizing on current valuation. Exercise caution and review recent earnings quality and management commentary.