Spruce Biosciences, Inc.

Spruce Biosciences, Inc.

SPRBยทNASDAQ

$53.16

+8.1%
HealthcareBiotechnology

Spruce Biosciences, Inc., a biopharmaceutical company, focuses on developing and commercializing novel therapies for rare endocrine disorders. The company engages in developing tildacerfont, a non-steroidal therapy to enhance disease control and reduce steroid burden for adult patients suffering from congenital adrenal hyperplasia (CAH), which is in Phase 2b clinical trial; and to evaluate glucocorticoid reduction and clinical consequences in adult patients with classic CAH that is Phase 2b clinical trial. It is also developing tildacerfont for the treatment of pediatric classic congenital adrenal hyperplasia in children that is in Phase 2 clinical trial; and for females with polycystic ovary syndrome, which is in Phase 2 clinical trial. The company has a license agreement with Eli Lilly and Company to research, develop, and commercialize compounds for various pharmaceutical uses. Spruce Biosciences, Inc. was incorporated in 2014 and is headquartered in Daly City, California.

At a Glance

Live Snapshot
Market Cap$72.94M
EPS-50.8300
P/E Ratio-1.05
Earnings Date08/13/2026
3Y-20.0%
5Y+21.0%
10Y+289.0%
3Y-100.0%
5Y-100.0%
10Y-
3Y-18142.0%
5Y-76.0%
10Y-
SPRB

Spruce Biosciences, Inc. Cash Conversion Engine

SPRB ยท NASDAQ
Net Income-38.97M
Depreciation & Amortization21.00K
Stock-Based Compensation2.57M
Change in Working Capital-724.00K
Others3.77M
Capital Expenditures0.00
Free Cash Flow-33.33M

Cash Flow Quality Analysis

FCF Conversion Rate

85.5%

Strong cash conversion. Most reported earnings translate into actual cash flow, suggesting solid fundamentals.

FCF Growth Trend

+40.4%

Strong FCF growth demonstrates improving cash generation and business momentum. Positive signal for sustainability.

Working Capital Impact

-$724.00K

Minimal working capital impact on FCF. Changes in operating assets and liabilities well-managed.

Cash Flow Quality Insight

Working capital strain: Significant cash tied up in operations. Monitor receivables collection, inventory turns, and payment terms to optimize cash conversion cycle.

Spruce Biosciences, Inc. Cash Flow Statement

SPRB โ€ข NASDAQ

Spruce Biosciences, Inc. Cash Flow StatementDec 2025Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020Dec 2019Dec 2018
OPERATING ACTIVITIES
-39M
-53M
-47.9M
-46.2M
-42.3M
-29.5M
-13.1M
-9.9M
21K
46K
70K
429K
68K
36K
12K
1K
0.0
0.0
0.0
0.0
0.0
0.0
-446K
0.0
2.6M
5.3M
4.6M
0.0
4M
755K
196K
101K
3.8M
249K
-404K
2.9M
434K
66K
446K
-1.6M
-724K
-8.6M
10.4M
1.1M
2M
1.2M
263K
1.2M
-33.3M
-56M
-33.3M
-41.7M
-35.9M
-27.5M
-12.6M
-8.6M
INVESTING ACTIVITIES
(0.0)
(0.0)
-7K
-8K
-93K
-74K
-4K
(0.0)
(0.0)
(0.0)
-11.9M
-36.8M
-79.1M
(0.0)
(0.0)
(0.0)
0.0
0.0
67.7M
60.5M
0.0
0.0
0.0
0.0
(0.0)
(0.0)
(55.8M)
(23.7M)
-79.2M
-74K
-4K
(0.0)
FINANCING ACTIVITIES
50.1M
246K
53.6M
-201K
0.0
93.4M
0.0
0.0
-2.1M
-1.6M
-1.6M
0.0
220K
0.0
4.5M
0.0
-4.5M
-246K
-2.9M
-40K
423K
51K
0.0
0.0
43.5M
-1.6M
49.1M
-241K
643K
181M
12.4M
0.0
CASH FLOW SUMMARY
0.0
0.0
0.0
187K
0.0
0.0
0.0
0.0
10.2M
-57.6M
71.6M
-18M
-114.4M
153.4M
-188K
-8.6M
38.8M
96.3M
24.7M
42.7M
157.4M
3.9M
4.1M
12.7M
48.9M
38.8M
96.4M
24.7M
43M
157.4M
3.9M
4.1M
-33.3M
-56M
-33.3M
-41.7M
-36M
-27.6M
-12.6M
-8.6M

SEC Filings

SPRB - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
8-K

8-K 2026

N/A

May 26, 2026
May 21, 2026
2026
10-Q

10-Q 2026 Q1

Q1

May 13, 2026
March 31, 2026
2026
8-K

8-K 2026

N/A

May 13, 2026
May 13, 2026
2026
8-K

8-K 2026

N/A

April 22, 2026
April 20, 2026
2026
DEF 14A

DEF 14A 2026

N/A

April 09, 2026
April 09, 2026
2026
8-K

8-K 2026

N/A

March 20, 2026
March 16, 2026
2026
10-K

10-K 2025 FY

FY

March 09, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

March 09, 2026
March 09, 2026
2026
8-K

8-K 2026

N/A

February 05, 2026
February 05, 2026
2026
8-K

8-K 2026

N/A

January 08, 2026
January 07, 2026
2026
Showing 1 to 10 of 97 filings