Spruce Biosciences, Inc.

Spruce Biosciences, Inc.

SPRBยทNASDAQ

$53.16

+8.1%
HealthcareBiotechnology

Spruce Biosciences, Inc., a biopharmaceutical company, focuses on developing and commercializing novel therapies for rare endocrine disorders. The company engages in developing tildacerfont, a non-steroidal therapy to enhance disease control and reduce steroid burden for adult patients suffering from congenital adrenal hyperplasia (CAH), which is in Phase 2b clinical trial; and to evaluate glucocorticoid reduction and clinical consequences in adult patients with classic CAH that is Phase 2b clinical trial. It is also developing tildacerfont for the treatment of pediatric classic congenital adrenal hyperplasia in children that is in Phase 2 clinical trial; and for females with polycystic ovary syndrome, which is in Phase 2 clinical trial. The company has a license agreement with Eli Lilly and Company to research, develop, and commercialize compounds for various pharmaceutical uses. Spruce Biosciences, Inc. was incorporated in 2014 and is headquartered in Daly City, California.

At a Glance

Live Snapshot
Market Cap$72.94M
EPS-50.8300
P/E Ratio-1.05
Earnings Date08/13/2026
3Y-
5Y-
10Y-
3Y-16.0%
5Y+32.0%
10Y+295.0%
3Y-20.0%
5Y+21.0%
10Y+289.0%
Spruce Biosciences, Inc.

Spruce Biosciences, Inc. Profit Bridge

SPRB ยท NASDAQ
Revenue0.00
Cost of Goods Sold (21.00K)
Gross Profit-21.00K
Operating Expenses (36.51M)
Operating Income-36.51M
Interest Expense (90.00K)
Other Income/Expense-2.45M
Pretax Income-38.97M
Income Tax (0.00)
Net Income-38.97M
Net Income
-38.97M

Profitability Analysis

Spruce Biosciences, Inc. Income Statement

SPRB โ€ข NASDAQ

Spruce Biosciences, Inc. Income StatementDec 2025Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020Dec 2019Dec 2018
REVENUE
0.0
4.9M
10.1M
0.0
0.0
0.0
0.0
0.0
GROSS PROFIT
(21K)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(12K)
(1K)
-21K
4.9M
10.1M
0.0
0.0
0.0
-12K
-1K
OPERATING INCOME
(36.5M)
(61.1M)
(62.1M)
(47.3M)
(42.1M)
(29.4M)
(13.1M)
(10M)
(17M)
(14.6M)
(12.7M)
(12.1M)
(11.4M)
(5.6M)
(2.3M)
(1.6M)
(19.5M)
(46.4M)
(49.4M)
(35.2M)
(30.7M)
(23.9M)
(10.8M)
(8.4M)
-36.5M
-56.2M
-52M
-47.3M
-42.1M
-29.4M
-13.1M
-10M
PRE-TAX INCOME
(90K)
(307K)
(483K)
(420K)
(345K)
(323K)
(65K)
(0.0)
-90K
3.1M
4.1M
1.1M
-226K
-200K
-46K
0.0
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(84K)
(0.0)
-2.5M
3.1M
4.1M
1.1M
-226K
-123K
19K
114K
-39M
-53M
-47.9M
-46.2M
-42.3M
-29.5M
-13.1M
-9.9M
NET INCOME
-39M
-53M
-47.9M
-46.2M
-42.3M
-29.5M
-13.2M
-9.9M

SEC Filings

SPRB - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
8-K

8-K 2026

N/A

May 26, 2026
May 21, 2026
2026
10-Q

10-Q 2026 Q1

Q1

May 13, 2026
March 31, 2026
2026
8-K

8-K 2026

N/A

May 13, 2026
May 13, 2026
2026
8-K

8-K 2026

N/A

April 22, 2026
April 20, 2026
2026
DEF 14A

DEF 14A 2026

N/A

April 09, 2026
April 09, 2026
2026
8-K

8-K 2026

N/A

March 20, 2026
March 16, 2026
2026
10-K

10-K 2025 FY

FY

March 09, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

March 09, 2026
March 09, 2026
2026
8-K

8-K 2026

N/A

February 05, 2026
February 05, 2026
2026
8-K

8-K 2026

N/A

January 08, 2026
January 07, 2026
2026
Showing 1 to 10 of 97 filings