Summit Therapeutics Inc.

Summit Therapeutics Inc.

SMMTยทNASDAQ

$15.07

+1.4%
HealthcareBiotechnology

Summit Therapeutics Inc., a biopharmaceutical company, discovers, develops, and commercializes medicines to treat infectious diseases in the United States and Latin America. It conducts clinical programs focusing on Clostridioides difficile infection (CDI). The company's lead product candidate is ridinilazole, an orally administered small molecule antibiotic that is in Phase III clinical trials for the treatment of CDI. It also offers SMT-738, for combating multidrug resistant infections primarily carbapenem-resistant Enterobacteriaceae infections; and DDS-04 series for the potential treatment of infections caused by the Enterobacteriaceae. The company was founded in 2003 and is based in Cambridge, Massachusetts.

At a Glance

Live Snapshot
Market Cap$11.68B
EPS-1.4400
P/E Ratio-10.47
Earnings Date08/10/2026

Intrinsic Alpha Methodology

Thesis Lenses

Signal ยท Driver ยท Risk

Signal

Medium confidence

Valuation multiple is compressed (P/E -10.5).

Valuation inputs: P/E -10.5, earnings yield N/A, momentum +1.4%.

If multiples stay elevated while momentum fades, downside repricing risk rises.

Driver

High confidence

Return profile is soft (ROE -1.6%, ROIC -1.6%).

Profitability stack: net margin 0.0%, ROE -1.6%, ROIC -1.6%.

Quality deterioration often appears in margins before it shows up in headline EPS.

Risk

High confidence

Risk profile is balanced but has notable pressure points to monitor.

Risk factors: liabilities/assets +12.3%, momentum +1.4%, net margin 0.0%.

Higher leverage with weak momentum and thin margins can amplify drawdown severity.

smmt

Summit Therapeutics Inc. Market vs Earnings Trajectory

SMMT ยท NASDAQ

Loading price and EPS data...

Summit Therapeutics Inc.

Summit Therapeutics Inc. Fair Value Envelope

SMMT ยท NASDAQ

Our analysis suggests that SMMT has a fair value of HIDDEN per share in the Base Case projection. With shares currently trading at $15.07, this represents a potential HIDDEN relative to our calculated worth for Summit Therapeutics Inc..

Intrinsic Value
Current Price: $15.07
3Y+251.0%
5Y+89.0%
10Y+235.0%
3Y-100.0%
5Y-100.0%
10Y-100.0%
3Y+1270.0%
5Y+1949.0%
10Y+4952.0%
3Y+677.0%
5Y+571.0%
10Y-2228.0%
3Y+667.0%
5Y+567.0%
10Y-2248.0%
3Y+13.0%
5Y+633.0%
10Y+1499.0%
Summit Therapeutics Inc.

Summit Therapeutics Inc. Profit Bridge

SMMT ยท NASDAQ
Revenue0.00
Cost of Goods Sold (0.00)
Gross Profit0.00
Operating Expenses (1.09B)
Operating Income-1.09B
Interest Expense (0.00)
Other Income/Expense14.84M
Pretax Income-1.08B
Income Tax (0.00)
Net Income-1.08B
Net Income
-1.08B

Profitability Analysis

0.00%
Gross Profit Margin
3Y-100.0%
5Y-100.0%
10Y-100.0%
0.00%
Operating Profit Margin
3Y-100.0%
5Y-100.0%
10Y-100.0%
0.00%
Net Profit Margin
3Y-100.0%
5Y-100.0%
10Y-100.0%
-163.86%
Return on Equity
188%
3Y+163.0%
5Y+147.0%
10Y-133.0%
-143.72%
Return on Assets
183%
3Y+1112.0%
5Y+180.0%
10Y+216.0%
-160.56%
Return on Invested Capital
202%
3Y+1285.0%
5Y+152.0%
10Y+107.0%
SMMT

Summit Therapeutics Inc. Cash Conversion Engine

SMMT ยท NASDAQ
Net Income-1.08B
Depreciation & Amortization-6.86M
Stock-Based Compensation732.42M
Change in Working Capital23.32M
Others7.78M
Capital Expenditures-657.00K
Free Cash Flow-323.59M

Cash Flow Quality Analysis

FCF Conversion Rate

30.0%

Weak cash conversion. Significant portion of earnings not converting to cashโ€”review working capital trends and capital intensity.

CapEx Intensity

-0.2%

Asset-light business model. Low capital requirements leave more cash available for shareholders and growth investments.

FCF Growth Trend

-127.5%

Significant FCF decline raises concerns. Urgent review needed of operational performance and capital allocation.

Working Capital Impact

+$23.32M

Working capital inflow boosted cash flow. Efficient management of receivables, inventory, and payables contributing positively.

Cash Flow Quality Insight

Deteriorating cash generation: Both declining FCF and weak conversion rate signal fundamental challenges. Investigate margin pressure, rising costs, or working capital issues.

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Summit Therapeutics Inc. Funding & Solvency Profile

SMMT ยท NASDAQ
Cash & Cash Equivalents106.52M
Net Receivables0.00
Inventory0.00
Other Current Assets17.87M
Total Current Assets617 M
Property, Plant & Equipment21.06M
Goodwill & Intangible Assets1.97M
Long-Term Investments0.00
Other Non-Current Assets8.23M
Total Non-Current Assets29 M
Total Assets
647.86M

Financial Health Analysis

Current Ratio

7.41x

Excellent liquidity position. The company can easily cover its short-term obligations with substantial cushion.

Debt-to-Equity Ratio

0.19x

Conservative capital structure. The company relies primarily on equity financing, indicating low financial risk.

Working Capital

533 M

Strong working capital position provides significant operational flexibility and financial cushion.

Asset Composition

95% Current

Asset-light business model with high liquidity. Majority of assets are easily convertible to cash.

Financial Health Insight

Strong financial foundation: Excellent liquidity combined with conservative leverage suggests the company is well-positioned to weather economic uncertainties and fund growth opportunities.

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Summit Therapeutics Inc. Street Expectations Map

SMMT ยท NASDAQ

Wall Street analysts project that SMMT stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 19.00, with estimates ranging from a low of 16.00 to a high of 23.00.

Lowest Target
16.00
6.17%
Consensus Target
19.00
26.08%
Highest Target
23.00
52.62%

The consensus 1-year price target stands at 19.00, with estimates ranging from a low of 16.00 to a high of 23.00.

Analyst Consensus Analysis

Upside Potential

+26.1%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

36.8% spread

Good consensus alignment. Moderate target spread reflects general agreement on value drivers with some variance in assumptions.

Analyst Conviction

High

Positive outlook with reasonable agreement. Analysts generally optimistic about prospects with manageable uncertainty.

Market Sentiment Insight

Monitor and evaluate: Current analyst consensus suggests limited conviction or near-term catalysts. Stay informed on company developments and reassess positioning as new information emerges.

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Summit Therapeutics Inc. Insider Positioning

SMMT ยท NASDAQ

During the last 12 months, insiders have purchased $22.97M worth of SMMT shares, with no selling activity reported.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

1.3M

22.97M

Sold

0

0.00

Net Activity

+23.0M

+$22.97M

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

1
XY

Xia Yu

Director

533.6K sharesโ€ข1 transactions

$10.00M

2
DRW

Duggan Robert W

Director, 10 Percent Owner, Officer: Co-Chief Executive Officer

365.1K sharesโ€ข3 transactions

$6.48M

3
ZM

Zanganeh Mahkam

Director, 10 Percent Owner, Officer: Co-Chief Executive Officer

365.1K sharesโ€ข3 transactions

$6.48M

Top Sellers

No selling activity

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $22.97M net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

โˆž:1

Perfect buy/sell ratio. Only buying activity with zero sellingโ€”the most bullish possible insider signal.

Insider Participation

High Buying

3 insider buyers vs. 0 sellers. Broad-based buying across management team suggests widespread confidence.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.

No Dividend Yield Data

SMMT has not reported any dividend yield values in the available annual periods.

ย 

smmt Dividend History

SMMT
10Y CAGR +0%
Latest $0
Annual $0
Stable dividend payments
Last Period: +0%