Summit Therapeutics Inc.

Summit Therapeutics Inc.

SMMT·NASDAQ

$15.07

+1.4%
HealthcareBiotechnology

Summit Therapeutics Inc., a biopharmaceutical company, discovers, develops, and commercializes medicines to treat infectious diseases in the United States and Latin America. It conducts clinical programs focusing on Clostridioides difficile infection (CDI). The company's lead product candidate is ridinilazole, an orally administered small molecule antibiotic that is in Phase III clinical trials for the treatment of CDI. It also offers SMT-738, for combating multidrug resistant infections primarily carbapenem-resistant Enterobacteriaceae infections; and DDS-04 series for the potential treatment of infections caused by the Enterobacteriaceae. The company was founded in 2003 and is based in Cambridge, Massachusetts.

At a Glance

Live Snapshot
Market Cap$11.68B
EPS-1.4400
P/E Ratio-12.11
Earnings Date08/10/2026
-160.56%
Return on Invested Capital
202%
3Y+1285.0%
5Y+152.0%
10Y+107.0%
-163.86%
Return on Equity
188%
3Y+163.0%
5Y+147.0%
10Y-133.0%
-143.72%
Return on Assets
183%
3Y+1112.0%
5Y+180.0%
10Y+216.0%
Summit Therapeutics Inc.

Summit Therapeutics Inc. Management Team

SMMT · NASDAQ
MB

Mr. Bhaskar Anand

Chief Accounting Officer

Born 1977(Age 49)
male
DF

Dr. Fong Clow

Chief Biometrics Officer

MD

Mr. Dave Gancarz

Chief Business & Strategy Officer

male
MS

Ms. Shelley D. Spray

Chief Education & Brand Officer

Born 1965(Age 61)
female
DA

Dr. Allen S. Yang M.D., Ph.D.

Chief Medical Officer

Born 1968(Age 58)
MM

Mr. Manmeet Singh Soni CPA

Chief Operating Officer, Chief Financial Officer & Director

Compensation

$1,261,021

Born 1978(Age 48)
male
DU

Dr. Urte Gayko Ph.D.

Chief Regulatory, Quality & Pharmacovigilance Officer

Born 1971(Age 55)
MR

Mr. Robert W. Duggan

Co-Chief Executive Officer & Executive Chairman

Compensation

$158,613

Born 1944(Age 82)
male
DM

Dr. Mahkam Zanganeh D.D.S., M.B.A.

Co-Chief Executive Officer, President & Director

Compensation

$1,161,021

Born 1970(Age 56)
PD

Prof. Dame Kay Davies DBE, FRS CBE

Co-Founder, Chairman of Scientific Advisory Board and Scientific Advisor

Born 1951(Age 75)
DA

Dr. Allen S. Yang M.D., Ph.D.

Head of R&D Strategy

Born 1968(Age 58)
MN

Mr. Nathan LiaBraaten

Senior Director of Investor Relations

male
smmt

Summit Therapeutics Inc. Insider Positioning

SMMT · NASDAQ

During the last 12 months, insiders have purchased $22.97M worth of SMMT shares, with no selling activity reported.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

1.3M

22.97M

Sold

0

0.00

Net Activity

+23.0M

+$22.97M

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

1
XY

Xia Yu

Director

533.6K shares1 transactions

$10.00M

2
DRW

Duggan Robert W

Director, 10 Percent Owner, Officer: Co-Chief Executive Officer

365.1K shares3 transactions

$6.48M

3
ZM

Zanganeh Mahkam

Director, 10 Percent Owner, Officer: Co-Chief Executive Officer

365.1K shares3 transactions

$6.48M

Top Sellers

No selling activity

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $22.97M net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

∞:1

Perfect buy/sell ratio. Only buying activity with zero selling—the most bullish possible insider signal.

Insider Participation

High Buying

3 insider buyers vs. 0 sellers. Broad-based buying across management team suggests widespread confidence.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.

SEC Filings

SMMT - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 17, 2026
April 17, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 29, 2025
June 12, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 25, 2024
June 14, 2024
2024
DEF 14A

DEF 14A 2023

N/A

September 19, 2023
October 12, 2023
2023
DEF 14A

DEF 14A 2023

N/A

April 21, 2023
May 23, 2023
2023
DEF 14A

DEF 14A 2023

N/A

December 13, 2022
January 06, 2023
2023
DEF 14A

DEF 14A 2022

N/A

July 06, 2022
July 06, 2022
2022
DEF 14A

DEF 14A 2022

N/A

April 29, 2022
June 15, 2022
2022
DEF 14A

DEF 14A 2021

N/A

April 29, 2021
June 16, 2021
2021
Showing 1 to 9 of 9 filings