Soleno Therapeutics, Inc.

Soleno Therapeutics, Inc.

SLNO·NASDAQ

$53.01

+0.038%
HealthcareBiotechnology

Soleno Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of novel therapeutics for the treatment of rare diseases. Its lead candidate is Diazoxide Choline Controlled-Release, a once-daily oral tablet for the treatment of Prader-Willi Syndrome, which is being evaluated in an ongoing Phase III clinical development program. The company was formerly known as Capnia, Inc. and changed its name to Soleno Therapeutics, Inc. in May 2017. Soleno Therapeutics, Inc. was incorporated in 1999 and is based in Redwood City, California.

At a Glance

Live Snapshot
Market Cap$2.76B
EPS0.4100
P/E Ratio117.86
Earnings Date08/05/2026
2.97%
Return on Invested Capital
-105%
3Y-102.0%
5Y-105.0%
10Y-101.0%
4.64%
Return on Equity
-106%
3Y-102.0%
5Y-109.0%
10Y-101.0%
3.71%
Return on Assets
-107%
3Y-104.0%
5Y-110.0%
10Y-102.0%
Soleno Therapeutics, Inc.

Soleno Therapeutics, Inc. Management Team

SLNO · NASDAQ
DA

Dr. Anish Bhatnagar M.D.

Chairman, President, Chief Executive Officer & Chief Operating Officer

Compensation

$1,046,200

Born 1970(Age 56)
MM

Ms. Meredith Manning M.B.A.

Chief Commercial Officer

Compensation

$605,161

Born 1972(Age 54)
female
MJ

Mr. James H. MacKaness

Chief Financial Officer & Compliance Officer

Compensation

$656,200

Born 1964(Age 62)
male
MJ

Mr. Jesse Schumaker

General Counsel

male
DM

Dr. Michael Huang M.D.

Senior Vice President of Clinical Development

Born 1974(Age 52)
DN

Dr. Neil M. Cowen M.B.A., Ph.D.

Senior Vice President of Drug Development

MK

Ms. Kristen Yen M.S.

Senior Vice President of Global Clinical Operations and Patient Advocacy

Compensation

$317,190

Born 1969(Age 57)
female
DM

Dr. Mitchell Nagao M.B.A., Pharm.D.

Senior Vice President of Medical Affairs

ML

Ms. Lauren Budesheim

Senior Vice President of People

female
MP

Ms. Patricia C. Hirano M.P.H.

Senior Vice President of Regulatory Affairs

Compensation

$515,813

Born 1966(Age 60)
female
ML

Ms. Lauren Budesheim

Vice President of People

female
slno

Soleno Therapeutics, Inc. Insider Positioning

SLNO · NASDAQ

During the last 12 months, insiders have sold $485K worth of SLNO shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

4.9K

146.10K

Net Activity

-146K

-$146K

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

9-12 Months

Bought

0

0.00

Sold

4.1K

339.38K

Net Activity

-339K

-$339K

Top Buyers

No buying activity

Top Sellers

1
HPC

Hirano Patricia C

Officer: See Remarks

4.1K shares•2 transactions

$339K

2
MM

Manning Meredith

Officer: Chief Commercial Officer

4.9K shares•1 transactions

$146K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $485K net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$146K

Heavy recent selling activity. Recent insider sales notably exceed purchases—may warrant investigation into company developments.

Insider Participation

High Selling

2 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Persistent selling pressure: Consistent insider selling with weak buy/sell ratio suggests insiders may be capitalizing on current valuation. Exercise caution and review recent earnings quality and management commentary.

SEC Filings

SLNO - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2025

N/A

April 22, 2025
June 05, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 22, 2024
June 06, 2024
2024
DEF 14A

DEF 14A 2023

N/A

April 14, 2023
May 25, 2023
2023
DEF 14A

DEF 14A 2022

N/A

April 21, 2022
June 01, 2022
2022
DEF 14A

DEF 14A 2021

N/A

April 21, 2021
June 01, 2021
2021
DEF 14A

DEF 14A 2020

N/A

October 19, 2020
November 10, 2020
2020
DEF 14A

DEF 14A 2020

N/A

April 20, 2020
May 18, 2020
2020
DEF 14A

DEF 14A 2019

N/A

April 29, 2019
June 10, 2019
2019
DEF 14A

DEF 14A 2018

N/A

April 30, 2018
June 11, 2018
2018
DEF 14A

DEF 14A 2017

N/A

April 13, 2017
May 08, 2017
2017
Showing 1 to 10 of 14 filings