Soleno Therapeutics, Inc.

Soleno Therapeutics, Inc.

SLNOยทNASDAQ

$53.01

+0.038%
HealthcareBiotechnology

Soleno Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of novel therapeutics for the treatment of rare diseases. Its lead candidate is Diazoxide Choline Controlled-Release, a once-daily oral tablet for the treatment of Prader-Willi Syndrome, which is being evaluated in an ongoing Phase III clinical development program. The company was formerly known as Capnia, Inc. and changed its name to Soleno Therapeutics, Inc. in May 2017. Soleno Therapeutics, Inc. was incorporated in 1999 and is based in Redwood City, California.

At a Glance

Live Snapshot
Market Cap$2.76B
EPS0.4100
P/E Ratio117.86
Earnings Date08/05/2026
slno

Soleno Therapeutics, Inc. Street Expectations Map

SLNO ยท NASDAQ

Wall Street analysts project that SLNO stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 80.00, with estimates ranging from a low of 53.00 to a high of 107.00.

Lowest Target
53.00
-0.02%
Consensus Target
80.00
50.91%
Highest Target
107.00
101.85%

The consensus 1-year price target stands at 80.00, with estimates ranging from a low of 53.00 to a high of 107.00.

Analyst Consensus Analysis

Upside Potential

+50.9%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

67.5% spread

High uncertainty. Very wide target spread indicates significant disagreement among analystsโ€”major valuation uncertainty or transformation underway.

Risk-Reward Profile

5399.00x

Favorable risk-reward. Potential upside significantly exceeds downside risk, offering asymmetric return profile attractive for risk-tolerant investors.

Analyst Conviction

Low

High uncertainty: Wide dispersion indicates analysts struggle to agree on valuationโ€”proceed with caution and independent analysis.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

slno

Soleno Therapeutics, Inc. Forward Estimates of Revenue

SLNO ยท NASDAQ
Latest Revenue
190.41M
FY 2025
Avg Estimate
462.06M
FY 2026
Estimate Range
441.73M - 488.27M
Analyst Spread

Forward Growth Analysis

Projected Growth+142.7%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread10%

Reasonable estimate spread indicates general agreement with normal forecast variance.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

slno

Soleno Therapeutics, Inc. Forward Estimates of Net Income

SLNO ยท NASDAQ
Latest Net Income
20.89M
FY 2025
Avg Estimate
209.28M
FY 2026
Estimate Range
178.85M - 262.35M
Analyst Spread

Forward Growth Analysis

Projected Growth+901.8%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread40%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

slno

Soleno Therapeutics, Inc. Forward Estimates of EPS

SLNO ยท NASDAQ
Latest EPS
0.41
FY 2025
Avg Estimate
$3.81
FY 2026
Estimate Range
$3.29 - $4.83
Analyst Spread

Forward Growth Analysis

Projected Growth+829.5%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage7 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread40%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

slno

Soleno Therapeutics, Inc. Forward Estimates of EBIT

SLNO ยท NASDAQ
Latest EBIT
26.37M
FY 2025
Avg Estimate
382.45M
FY 2026
Estimate Range
365.61M - 404.13M
Analyst Spread

Forward Growth Analysis

Projected Growth+1350.5%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread10%

Reasonable estimate spread indicates general agreement with normal forecast variance.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

slno

Soleno Therapeutics, Inc. Forward Estimates of EBITDA

SLNO ยท NASDAQ
Latest EBITDA
28.38M
FY 2025
Avg Estimate
383.43M
FY 2026
Estimate Range
366.55M - 405.17M
Analyst Spread

Forward Growth Analysis

Projected Growth+1250.9%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread10%

Reasonable estimate spread indicates general agreement with normal forecast variance.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

slno

Soleno Therapeutics, Inc. Forward Estimates of SG&A Expense

SLNO ยท NASDAQ
Latest SG&A Expense
132.13M
FY 2025
Avg Estimate
433.78M
FY 2026
Estimate Range
414.69M - 458.38M
Analyst Spread

Forward Growth Analysis

Projected Growth+228.3%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage6 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread10%

Reasonable estimate spread indicates general agreement with normal forecast variance.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

slno

Soleno Therapeutics, Inc. Insider Positioning

SLNO ยท NASDAQ

During the last 12 months, insiders have sold $485K worth of SLNO shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

4.9K

146.10K

Net Activity

-146K

-$146K

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

9-12 Months

Bought

0

0.00

Sold

4.1K

339.38K

Net Activity

-339K

-$339K

Top Buyers

No buying activity

Top Sellers

1
HPC

Hirano Patricia C

Officer: See Remarks

4.1K sharesโ€ข2 transactions

$339K

2
MM

Manning Meredith

Officer: Chief Commercial Officer

4.9K sharesโ€ข1 transactions

$146K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $485K net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$146K

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

High Selling

2 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Persistent selling pressure: Consistent insider selling with weak buy/sell ratio suggests insiders may be capitalizing on current valuation. Exercise caution and review recent earnings quality and management commentary.