Sionna Therapeutics, Inc.

Sionna Therapeutics, Inc.

SION·NASDAQ

$36.70

-10%
HealthcareBiotechnology

Sionna Therapeutics, Inc. is a biopharmaceutical company. The Company provides treatment paradigm for cystic fibrosis patients by developing medicines that normalize the function of the cystic fibrosis transmembrane conductance regulator.

At a Glance

Live Snapshot
Market Cap$1.66B
EPS-1.8800
P/E Ratio-19.52
Earnings Date08/10/2026
-28.20%
Return on Invested Capital
-29%
3Y-46.0%
5Y-46.0%
10Y-46.0%
-24.53%
Return on Equity
-165%
3Y-143.0%
5Y-143.0%
10Y-143.0%
-23.09%
Return on Assets
-30%
3Y-50.0%
5Y-50.0%
10Y-50.0%
Sionna Therapeutics, Inc.

Sionna Therapeutics, Inc. Management Team

SION · NASDAQ
ME

Ms. Elena H. Ridloff C.F.A.

Chief Financial Officer & Head of Corporate Development

Compensation

$647,922

Born 1980(Age 46)
female
MJ

Ms. Jennifer Fitzpatrick J.D.

Chief Legal Officer

Born 1977(Age 49)
female
DC

Dr. Charlotte McKee M.D.

Chief Medical Officer

Compensation

$647,922

Born 1965(Age 61)
MV

Ms. Vanya Sagar

Chief People Officer

Born 1976(Age 50)
female
DG

Dr. Greg Hurlbut Ph.D.

Co-Founder & Senior Vice President of Discovery Research

DM

Dr. Mark Munson Ph.D.

Co-founder & Senior Vice President of Medicinal Chemistry

MM

Mr. Michael Cloonan M.B.A.

President, Chief Executive Officer & Director

Compensation

$784,593

Born 1972(Age 54)
male
MM

Ms. Mara Furlow M.S.

Senior Vice President of Global Regulatory Affairs & Quality

female
MA

Mr. Andy Chu

Vice President of Information & Technology

male
MM

Ms. Meghan Bagshaw

Vice President of Programs, Portfolio & Operations

female
sion

Sionna Therapeutics, Inc. Insider Positioning

SION · NASDAQ

During the last 12 months, insiders have sold $104.66M worth of SION shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

1.7M

77.57M

Net Activity

-77.6M

-$77.57M

3-6 Months

Bought

0

0.00

Sold

392.6K

16.25M

Net Activity

-16.2M

-$16.25M

6-9 Months

Bought

0

0.00

Sold

246.5K

10.84M

Net Activity

-10.8M

-$10.84M

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

No buying activity

Top Sellers

1
TPA

Thompson Peter A.

Director

1.0M shares18 transactions

$46.55M

2
OAL

Orbimed Advisors Llc

Director

1.0M shares18 transactions

$46.55M

3
TGAL

Tpg Gp A, Llc

10 Percent Owner

250.0K shares1 transactions

$10.00M

4
RCML

Ra Capital Management, L.P.

Director, 10 Percent Owner:

20.1K shares4 transactions

$795K

5
FJ

Fitzpatrick Jennifer

Officer: Chief Legal Officer

20.5K shares2 transactions

$762K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $104.66M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$77.57M

Heavy recent selling activity. Recent insider sales notably exceed purchases—may warrant investigation into company developments.

Insider Participation

High Selling

5 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.

SEC Filings

SION - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 27, 2026
June 17, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 29, 2025
June 12, 2025
2025
Showing 1 to 2 of 2 filings