Scilex Holding Company

Scilex Holding Company

SCLX·NASDAQ

$7.54

+1.8%
HealthcareDrug Manufacturers - General

Scilex Holding Company, a biopharmaceutical company, focuses on developing and commercializing non-opioid management products for the treatment of acute and chronic pain. Its commercial product is ZTlido 1.8%, a prescription lidocaine topical product for the relief of neuropathic pain related with post-herpetic neuralgia, which is a form of post-shingles nerve pain. It also offers SP-102, a viscous gel formulation of corticosteroid for epidural injections that is in a Phase III clinical trial to treat lumbosacral radicular pain; SP-103, which is in Phase II clinical trail for the treatment of low back pain; and SP-104, a novel low-dose delayed-release naltrexone hydrochloride formulation that has completed Phase I clinical trial for the treatment of fibromyalgia. The company is headquartered in Palo Alto, California. Scilex Holding Company is a subsidiary of Sorrento Therapeutics, Inc.

At a Glance

Live Snapshot
Market Cap$64.02M
EPS-36.4800
P/E Ratio-0.21
Earnings Date06/03/2026
1031.65%
Return on Invested Capital
1522%
3Y-964.0%
5Y-1047.0%
10Y-
172.65%
Return on Equity
357%
3Y-368.0%
5Y+415.0%
10Y-
-98.29%
Return on Assets
25%
3Y+264.0%
5Y+69.0%
10Y-
Scilex Holding Company

Scilex Holding Company Management Team

SCLX · NASDAQ
DH

Dr. Henry H. Ji Ph.D.

Executive Chairman

Compensation

$1,261,651

Born 1964(Age 62)
DE

Dr. Elaine K Chan Pharm.D.

Executive Director & Head of Medical Affairs

MS

Mr. Sumant Rajendran

Executive Director of Marketing

male
MS

Mr. Steven F. Lincoln J.D.

General Counsel & Chief Compliance Officer

male
MM

Mr. Mike Ciaffi

National Sales Director

male
MJ

Mr. Jaisim Shah

President, Chief Executive Officer & Director

Compensation

$1,266,574

Born 1960(Age 66)
male
MG

Ms. Gigi DeGuzman

Senior Executive Director & Chief of Staff

female
MS

Mr. Stephen Ma

Senior Vice President, Chief Financial Officer & Corporate Secretary

Compensation

$613,821

Born 1973(Age 53)
male
sclx

Scilex Holding Company Insider Positioning

SCLX · NASDAQ

During the last 12 months, insiders have purchased $8.90M and sold $13.55M worth of SCLX shares, resulting in $4.65M of net selling activity.

3 Months

Bought

3.9M

4.68M

Sold

650.0K

780.00K

Net Activity

+3.9M

+$3.90M

3-6 Months

Bought

0

0.00

Sold

20.7M

12.77M

Net Activity

-12.8M

-$12.77M

6-9 Months

Bought

240.0K

4.22M

Sold

0

0.00

Net Activity

+4.2M

+$4.22M

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

1
JH

Ji Henry

Director, Officer: Exec Chair, Ceo And President

3.4M shares2 transactions

$6.01M

2
MSH

Ma Stephen Hoi

Director, Officer: Cfo, Coo And Secretary

710.0K shares2 transactions

$1.83M

3
CJ

Chun Jay

Director

20.0K shares1 transactions

$352K

4
FD

Followwill Dorman

Director

20.0K shares1 transactions

$352K

5
WYA

Wu Yue Alexander

Director

20.0K shares1 transactions

$352K

Top Sellers

1
SHC

Scilex Holding Co

10 Percent Owner

20.7M shares3 transactions

$12.77M

2
JH

Ji Henry

Director, Officer: Exec Chair, Ceo And President

650.0K shares1 transactions

$780K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Slightly bearish with $4.65M net selling. Selling modestly exceeds buying, which could be routine diversification rather than concern.

Buy/Sell Ratio

0.66:1

Moderately negative ratio. Selling is roughly double the buying, which may be routine or signal caution.

Recent Trend (3 Months)

$3.90M

Very strong recent buying momentum. Recent insider purchases significantly outpace sales, suggesting near-term optimism.

Insider Participation

High Buying

5 insider buyers vs. 2 sellers. Broad-based buying across management team suggests widespread confidence.

SEC Filings

SCLX - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 30, 2026
June 24, 2026
2026
DEF 14A

DEF 14A 2025

N/A

November 07, 2025
December 11, 2025
2025
DEF 14A

DEF 14A 2025

N/A

May 16, 2025
June 04, 2025
2025
DEF 14A

DEF 14A 2025

N/A

February 27, 2025
March 19, 2025
2025
DEF 14A

DEF 14A 2024

N/A

March 12, 2024
April 05, 2024
2024
DEF 14A

DEF 14A 2023

N/A

March 08, 2023
April 06, 2023
2023
DEF 14A

DEF 14A 2022

N/A

June 07, 2022
June 30, 2022
2022
Showing 1 to 7 of 7 filings