Replimune Group, Inc.

Replimune Group, Inc.

REPL·NASDAQ

$9.98

+13%
HealthcareBiotechnology

Replimune Group, Inc., a biotechnology company, develops oncolytic immuno-gene therapies to treat cancer. It uses its proprietary Immunotherapy platform to design and develop product candidates that are intended to activate the immune system against cancer. The company's lead product candidate is RP1, a selectively replicating version of herpes simplex virus 1, which is in Phase I/II clinical trials for a range of solid tumors; and that is in Phase II clinical trials for patients with cutaneous squamous cell carcinoma. It is also developing RP2, which is in Phase I clinical trials for an anti-CTLA-4 antibody-like protein in order to block the inhibition of the immune response otherwise caused by CTLA-4; and RP3 that is in Phase I clinical trials to express immune-activating proteins that stimulate T cells. Replimune Group, Inc. was founded in 2015 and is headquartered in Woburn, Massachusetts.

At a Glance

Live Snapshot
Market Cap$824.07M
EPS-3.0700
P/E Ratio-3.25
Earnings Date06/04/2026
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Replimune Group, Inc. Street Expectations Map

REPL · NASDAQ

Wall Street analysts project that REPL stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 14.00, with estimates ranging from a low of 14.00 to a high of 14.00.

Lowest Target
14.00
40.28%
Consensus Target
14.00
40.28%
Highest Target
14.00
40.28%

The consensus 1-year price target stands at 14.00, with estimates ranging from a low of 14.00 to a high of 14.00.

Analyst Consensus Analysis

Upside Potential

+40.3%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

0.0% spread

High analyst agreement. Narrow target range indicates strong consensus on valuation, suggesting clear investment thesis and predictable outlook.

Analyst Conviction

Very High

Strong buy conviction: High upside with tight consensus suggests compelling investment opportunity backed by analyst confidence.

Market Sentiment Insight

Rare opportunity: Exceptional upside potential with strong analyst consensus creates a compelling setup. The combination of significant price target premium and tight agreement suggests high-conviction undervaluation that may attract institutional capital.

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Replimune Group, Inc. Forward Estimates of Revenue

REPL · NASDAQ
Latest Revenue
0.00
FY 2025
Avg Estimate
1.67M
FY 2026
Estimate Range
1.26M - 2.36M
Analyst Spread

Forward Growth Analysis

Analyst Coverage5 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread66%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

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Replimune Group, Inc. Forward Estimates of Net Income

REPL · NASDAQ
Latest Net Income
-247.30M
FY 2025
Avg Estimate
-258.57M
FY 2026
Estimate Range
-268.28M - -248.86M
Analyst Spread

Forward Growth Analysis

Projected Growth-4.6%

Declining expectations indicate headwinds—investigate whether temporary or structural issues.

Analyst Coverage5 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread8%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

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Replimune Group, Inc. Forward Estimates of EPS

REPL · NASDAQ
Latest EPS
-3.07
FY 2025
Avg Estimate
$-3.21
FY 2026
Estimate Range
$-3.33 - $-3.09
Analyst Spread

Forward Growth Analysis

Projected Growth-4.4%

Declining expectations indicate headwinds—investigate whether temporary or structural issues.

Analyst Coverage6 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread8%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

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Replimune Group, Inc. Forward Estimates of EBIT

REPL · NASDAQ
Latest EBIT
-259.85M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage5 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

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Replimune Group, Inc. Forward Estimates of EBITDA

REPL · NASDAQ
Latest EBITDA
-253.92M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage5 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

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Replimune Group, Inc. Forward Estimates of SG&A Expense

REPL · NASDAQ
Latest SG&A Expense
0.00
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Analyst Coverage5 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

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Replimune Group, Inc. Insider Positioning

REPL · NASDAQ

During the last 12 months, insiders have sold $944K worth of REPL shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

111.8K

637.09K

Net Activity

-637K

-$637K

3-6 Months

Bought

0

0.00

Sold

3.2K

32.96K

Net Activity

-33K

-$33K

6-9 Months

Bought

0

0.00

Sold

22.5K

224.65K

Net Activity

-225K

-$225K

9-12 Months

Bought

0

0.00

Sold

9.2K

49.16K

Net Activity

-49K

-$49K

Top Buyers

No buying activity

Top Sellers

1
PS

Patel Sushil

Director, Officer: Chief Executive Officer

47.3K shares•2 transactions

$301K

2
SC

Sarchi Christopher

Officer: Chief Commercial Officer

32.3K shares•4 transactions

$254K

3
XK

Xynos Konstantinos

Officer: Chief Medical Officer

21.3K shares•2 transactions

$137K

4
AP

Astley-Sparke Philip

Director

17.7K shares•1 transactions

$90K

5
HEL

Hill Emily Luisa

Officer: Chief Financial Officer

17.0K shares•2 transactions

$89K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $944K net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$637K

Heavy recent selling activity. Recent insider sales notably exceed purchases—may warrant investigation into company developments.

Insider Participation

High Selling

5 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.