Personalis, Inc.

Personalis, Inc.

PSNLยทNASDAQ

$10.78

-3.2%
HealthcareMedical - Diagnostics & Research

Personalis, Inc. operates as a cancer genomics company worldwide. The company provides sequencing and data analysis services to support the development of cancer therapies and large-scale genetic research programs. It offers NeXT Platform, which provides data analysis for tumor and its immune microenvironment, from a single limited tissue or plasma sample; ImmunoID Next for tumor profiling from tissue; NeXT Liquid Biopsy for tumor profiling from plasma; NeXT Personal, a liquid biopsy offering for personalized tumor tracking for patients; NeXT Dx Test, a genomic cancer profiling test enabling composite biomarkers for cancer treatment; and NeXT SHERPA and NeXT NEOPS for neoantigen prediction capabilities. The company also provides ACE platform for clinical and therapeutic applications such as neoantigen prediction, biomarker identification, and novel drug target selection. It serves biopharmaceutical customers, universities, non-profits, and government entities. The company has partnership with Mayo Clinic; MapKure, LLC; SpringWorks Therapeutics, Inc.; and Moores Cancer Center. Personalis, Inc. was incorporated in 2011 and is headquartered in Menlo Park, California.

At a Glance

Live Snapshot
Market Cap$957.31M
EPS-0.9100
P/E Ratio-11.85
Earnings Date08/04/2026
psnl

Personalis, Inc. Street Expectations Map

PSNL ยท NASDAQ

Wall Street analysts project that PSNL stock may experience modest gains over the coming 12 months. The consensus 1-year price target stands at 11.00, with estimates ranging from a low of 9.00 to a high of 13.00.

Lowest Target
9.00
-16.51%
Consensus Target
11.00
2.04%
Highest Target
13.00
20.59%

The consensus 1-year price target stands at 11.00, with estimates ranging from a low of 9.00 to a high of 13.00.

Analyst Consensus Analysis

Upside Potential

+2.0%

Fair value territory. Stock trading near consensus target suggests limited near-term catalysts. Focus on fundamental developments.

Analyst Agreement

36.4% spread

Good consensus alignment. Moderate target spread reflects general agreement on value drivers with some variance in assumptions.

Risk-Reward Profile

1.25x

Balanced risk-reward. Upside and downside potential relatively symmetric. Suitable for moderate risk tolerance with conviction in thesis.

Analyst Conviction

Moderate

Neutral sentiment. Fair value pricing with moderate agreement suggests wait-and-see approach or catalyst-driven opportunity.

Market Sentiment Insight

Monitor and evaluate: Current analyst consensus suggests limited conviction or near-term catalysts. Stay informed on company developments and reassess positioning as new information emerges.

psnl

Personalis, Inc. Forward Estimates of Revenue

PSNL ยท NASDAQ
Latest Revenue
0.00
FY 2025
Avg Estimate
84.11M
FY 2026
Estimate Range
82.85M - 85.36M
Analyst Spread

Forward Growth Analysis

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread3%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

psnl

Personalis, Inc. Forward Estimates of Net Income

PSNL ยท NASDAQ
Latest Net Income
-81.27M
FY 2025
Avg Estimate
-58.43M
FY 2026
Estimate Range
-61.73M - -55.13M
Analyst Spread

Forward Growth Analysis

Projected Growth+28.1%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread11%

Reasonable estimate spread indicates general agreement with normal forecast variance.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

psnl

Personalis, Inc. Forward Estimates of EPS

PSNL ยท NASDAQ
Latest EPS
-0.91
FY 2025
Avg Estimate
$-0.97
FY 2026
Estimate Range
$-1.04 - $-0.93
Analyst Spread

Forward Growth Analysis

Projected Growth-6.6%

Declining expectations indicate headwindsโ€”investigate whether temporary or structural issues.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread11%

Reasonable estimate spread indicates general agreement with normal forecast variance.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

psnl

Personalis, Inc. Forward Estimates of EBIT

PSNL ยท NASDAQ
Latest EBIT
-81.04M
FY 2025
Avg Estimate
-71.41M
FY 2026
Estimate Range
-72.47M - -70.34M
Analyst Spread

Forward Growth Analysis

Projected Growth+11.9%

Solid growth trajectory indicates healthy business performance and competitive positioning.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread3%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

psnl

Personalis, Inc. Forward Estimates of EBITDA

PSNL ยท NASDAQ
Latest EBITDA
-71.00M
FY 2025
Avg Estimate
-66.82M
FY 2026
Estimate Range
-67.81M - -65.82M
Analyst Spread

Forward Growth Analysis

Projected Growth+5.9%

Moderate growth expected, typical for mature businesses with stable market positions.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread3%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

psnl

Personalis, Inc. Forward Estimates of SG&A Expense

PSNL ยท NASDAQ
Latest SG&A Expense
53.57M
FY 2025
Avg Estimate
53.70M
FY 2026
Estimate Range
52.90M - 54.50M
Analyst Spread

Forward Growth Analysis

Projected Growth+0.2%

Flat growth suggests market maturity or near-term challenges offsetting expansion efforts.

Analyst Coverage5 Analysts

Moderate coverageโ€”sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread3%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

psnl

Personalis, Inc. Insider Positioning

PSNL ยท NASDAQ

During the last 12 months, insiders have purchased $1.15M and sold $2.74M worth of PSNL shares, resulting in $1.59M of net selling activity.

3 Months

Bought

0

0.00

Sold

118.9K

1.33M

Net Activity

-1.3M

-$1.33M

3-6 Months

Bought

120.7K

996.11K

Sold

1.2K

13.81K

Net Activity

+982K

+$982K

6-9 Months

Bought

13.9K

152.77K

Sold

133.3K

1.38M

Net Activity

-1.2M

-$1.23M

9-12 Months

Bought

0

0.00

Sold

1.1K

7.18K

Net Activity

-7K

-$7K

Top Buyers

1
TAI

Tempus Ai, Inc.

10 Percent Owner

134.6K sharesโ€ข5 transactions

$1.15M

Top Sellers

1
TA

Tachibana Aaron

Officer: Cfo And Coo

144.3K sharesโ€ข4 transactions

$1.58M

2
HCM

Hall Christopher M

Director, Officer: Chief Executive Officer

109.7K sharesโ€ข2 transactions

$1.15M

3
CR

Chen Richard

Officer: Chief Medical Officer And Evp

452 sharesโ€ข1 transactions

$3K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Negative insider sentiment with $1.59M net selling. Selling notably exceeds buying, warranting closer scrutiny of company fundamentals.

Buy/Sell Ratio

0.42:1

Weak buy/sell ratio. Selling significantly exceeds buyingโ€”monitor for potential fundamental concerns.

Recent Trend (3 Months)

$1.33M

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

High Selling

3 insider sellers vs. 1 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.