PRTA - NASDAQ
Prothena Corporation plc
$9.19
-2.9%Prothena Corporation plc, a late-stage clinical company, focuses on discovery and development of novel therapies for life-threatening diseases in the United States. The company is involved in developing Birtamimab, an investigational humanized antibody that is in Phase III clinical trial for the treatment of AL amyloidosis; Prasinezumab, a humanized monoclonal antibody, which is in Phase IIb clinical trial for the treatment of Parkinson's disease; PRX004 that completed Phase I clinical trial for the treatment of Transthyretin amyloidosis; and PRX005, which is in Phase I clinical trial for the treatment of Alzheimer's disease. Its discovery and preclinical programs include PRX012 for the treatment of Alzheimer's disease; and dual Aß-Tau vaccine for the treatment and prevention of Alzheimer's disease. Prothena Corporation plc has a license, development, and commercialization agreement with F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. to develop and commercialize antibodies that target alpha-synuclein; and a collaboration agreement with Bristol-Myers Squibb to develop antibodies. The company was founded in 2012 and is based in Dublin, Ireland.
At a Glance
Live SnapshotProthena Corporation plc Profit Bridge
Profitability Analysis
Gross Margin
Exceptional pricing power and cost management. The company retains over half of revenue after direct costs.
Operating Margin
Operating losses indicate the core business is unprofitable. Requires restructuring or revenue growth.
Net Profit Margin
Net losses indicate the company is burning cash. Sustainability depends on path to profitability.
Profitability Insight
Margin squeeze alert: Healthy gross margins but weak operating margins suggest excessive operating expenses. Cost optimization could unlock significant value.
Prothena Corporation plc Income Statement
PRTA • NASDAQ
| Prothena Corporation plc Income Statement | Dec 2025 | Dec 2024 | Dec 2023 | Dec 2022 | Dec 2021 | Dec 2020 | Dec 2019 | Dec 2018 | Dec 2017 | Dec 2016 | Dec 2015 | Dec 2014 | Dec 2013 | Dec 2012 | Dec 2011 | Dec 2010 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
REVENUE | ||||||||||||||||
9.7M | 135.2M | 91.4M | 53.9M | 200.6M | 853K | 814K | 955K | 27.5M | 1.1M | 1.6M | 50.9M | 676K | 2.7M | 507K | 1.2M | |
GROSS PROFIT | ||||||||||||||||
(3.7M) | (0.0) | (0.0) | (0.0) | (0.0) | (74.9M) | (50.8M) | (101.2M) | (134.5M) | (119.5M) | (58.4M) | (38.5M) | (26.1M) | (34.1M) | (0.0) | (0.0) | |
6M | 135.2M | 91.4M | 53.9M | 200.6M | -74M | -50M | -100.2M | -107M | -118.5M | -56.8M | 12.4M | -25.4M | -31.5M | 507K | 1.2M | |
OPERATING INCOME | ||||||||||||||||
(190.5M) | (289.7M) | (282.4M) | (185.5M) | (128.6M) | (38.7M) | (35.7M) | (143.7M) | (182.8M) | (160.6M) | (81.5M) | (57.5M) | (41.1M) | (44.1M) | (29.8M) | (13.4M) | |
(59.4M) | (67.2M) | (61.8M) | (49.9M) | (46.3M) | (38.7M) | (35.7M) | (42.5M) | (48.2M) | (41.1M) | (23.1M) | (19.1M) | (15.1M) | (9.9M) | (5.6M) | (3.6M) | |
(134.9M) | (222.5M) | (220.6M) | (135.6M) | (82.3M) | (75.1M) | (50.8M) | (101.2M) | (134.5M) | (119.5M) | (58.4M) | (38.5M) | (26.1M) | (34.1M) | (24.2M) | (9.8M) | |
-184.6M | -154.6M | -191M | -131.6M | 72M | -112.7M | -85.7M | -158.9M | -155.3M | -159.5M | -79.9M | -6.6M | -40.4M | -41.4M | -29.2M | -12.2M | |
PRE-TAX INCOME | ||||||||||||||||
(0.0) | (0.0) | (0.0) | (0.0) | (0.0) | (0.0) | (0.0) | (3.7M) | (3.7M) | (863K) | (0.0) | (0.0) | (0.0) | (0.0) | (0.0) | (0.0) | |
14.1M | 25.8M | 31M | 6.3M | 42K | 1.4M | 8.2M | 2.7M | -142K | 556K | 196K | 79K | 71K | 5K | 0.0 | 0.0 | |
-3.7M | (0.0) | (0.0) | (0.0) | (0.0) | -75.1M | -50.9M | (2.7M) | -2.3M | (571K) | (26K) | (310K) | -225K | (0.0) | (0.0) | (0.0) | |
-16.3M | 25.6M | 30.6M | 6M | -54K | 1.9M | 8.4M | 2.7M | -2.3M | 571K | 26K | 310K | -154K | 5K | 0.0 | 0.0 | |
-200.8M | -128.9M | -160.5M | -125.6M | 71.9M | -110.9M | -77.3M | -156.1M | -157.6M | -159M | -79.9M | -6.3M | -40.6M | -41.4M | -29.2M | -12.2M | |
NET INCOME | ||||||||||||||||
(43.3M) | -6.6M | -13.5M | -8.7M | (4.9M) | (283K) | (379K) | -470K | -4.4M | (1.1M) | (701K) | (811K) | (415K) | (6K) | (426K) | (320K) | |
-244.1M | -122.3M | -147M | -116.9M | 67M | -111.1M | -77.7M | -155.6M | -153.2M | -160.1M | -80.6M | -7.2M | -41M | -41.4M | -29.7M | -12.5M |
SEC Filings
PRTA - Filing history and reports
| Filing Type | Filing Date | Period Ending | Fiscal Year | Actions |
|---|---|---|---|---|
8-K 8-K 2026 N/A | May 15, 2026 | May 14, 2026 | 2026 | |
8-K 8-K 2026 N/A | May 07, 2026 | May 07, 2026 | 2026 | |
10-Q 10-Q 2026 Q1 Q1 | May 07, 2026 | March 31, 2026 | 2026 | |
DEF 14A DEF 14A 2026 N/A | March 27, 2026 | May 14, 2026 | 2026 | |
10-K 10-K 2025 FY FY | February 27, 2026 | December 31, 2025 | 2025 | |
8-K 8-K 2026 N/A | February 27, 2026 | February 27, 2026 | 2026 | |
8-K 8-K 2026 N/A | February 19, 2026 | February 19, 2026 | 2026 | |
8-K 8-K 2025 N/A | December 12, 2025 | December 10, 2025 | 2025 | |
8-K 8-K 2025 N/A | November 19, 2025 | November 19, 2025 | 2025 | |
8-K 8-K 2025 N/A | November 06, 2025 | November 06, 2025 | 2025 |
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