Prothena Corporation plc

Prothena Corporation plc

PRTAยทNASDAQ

$9.40

+2.3%
HealthcareBiotechnology

Prothena Corporation plc, a late-stage clinical company, focuses on discovery and development of novel therapies for life-threatening diseases in the United States. The company is involved in developing Birtamimab, an investigational humanized antibody that is in Phase III clinical trial for the treatment of AL amyloidosis; Prasinezumab, a humanized monoclonal antibody, which is in Phase IIb clinical trial for the treatment of Parkinson's disease; PRX004 that completed Phase I clinical trial for the treatment of Transthyretin amyloidosis; and PRX005, which is in Phase I clinical trial for the treatment of Alzheimer's disease. Its discovery and preclinical programs include PRX012 for the treatment of Alzheimer's disease; and dual AรŸ-Tau vaccine for the treatment and prevention of Alzheimer's disease. Prothena Corporation plc has a license, development, and commercialization agreement with F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. to develop and commercialize antibodies that target alpha-synuclein; and a collaboration agreement with Bristol-Myers Squibb to develop antibodies. The company was founded in 2012 and is based in Dublin, Ireland.

At a Glance

Live Snapshot
Market Cap$492.38M
EPS-4.5300
P/E Ratio-2.08
Earnings Date08/03/2026
3Y+50.0%
5Y+104.0%
10Y+39.0%
3Y-70.0%
5Y-30.0%
10Y-99.0%
3Y-100.0%
5Y-165.0%
10Y-100.0%
PRTA

Prothena Corporation plc Cash Conversion Engine

PRTA ยท NASDAQ
Net Income-244.09M
Depreciation & Amortization895.00K
Stock-Based Compensation37.64M
Change in Working Capital-4.17M
Others2.91M
Capital Expenditures-138.00K
Free Cash Flow-163.72M

Cash Flow Quality Analysis

FCF Conversion Rate

67.1%

Moderate conversion rate. Some gap between earnings and cash flow may warrant investigation into working capital or non-cash items.

CapEx Intensity

-0.1%

Asset-light business model. Low capital requirements leave more cash available for shareholders and growth investments.

FCF Growth Trend

-8.9%

Declining FCF warrants attention. Investigate whether due to temporary factors or fundamental deterioration.

Working Capital Impact

-$4.17M

Minimal working capital impact on FCF. Changes in operating assets and liabilities well-managed.

Cash Flow Quality Insight

Working capital strain: Significant cash tied up in operations. Monitor receivables collection, inventory turns, and payment terms to optimize cash conversion cycle.

Prothena Corporation plc Cash Flow Statement

PRTA โ€ข NASDAQ

Prothena Corporation plc Cash Flow StatementDec 2025Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020Dec 2019Dec 2018Dec 2017Dec 2016Dec 2015Dec 2014Dec 2013Dec 2012Dec 2011Dec 2010
OPERATING ACTIVITIES
-244.1M
-122.3M
-147M
-116.9M
67M
-111.1M
-77.7M
-155.6M
-153.2M
-160.1M
-80.6M
-7.2M
-41M
-41.4M
-29.7M
-12.5M
895K
893K
928K
744K
1.1M
1.5M
6.8M
3.2M
3.1M
2.4M
806K
743K
660K
468K
391K
191K
43.2M
-9.3M
-15.7M
-11.1M
4.6M
-1.7M
-1.2M
-1.6M
-2.2M
-3.2M
-963K
-990K
-538K
0.0
0.0
0.0
37.6M
46M
40.9M
31.3M
24.7M
22M
23.6M
27M
26.8M
24.9M
10.4M
5.6M
3.1M
6.1M
3M
1.6M
2.9M
2.7M
7.5M
6M
5.7M
5.5M
0.0
4.3M
1.6M
-156K
-3.6M
-261K
-29K
-1.1M
0.0
0.0
(0.0)
(3.2M)
(1.6M)
(2.7M)
(580K)
(1.4M)
(1.6M)
(0.0)
(294K)
(575K)
(442K)
(1.6M)
(796K)
(0.0)
(0.0)
(0.0)
-4.2M
-67.9M
-20.5M
-18.8M
-10.4M
3.5M
-4.4M
94.5M
-7.2M
18.9M
11.5M
1.4M
5.7M
-7.2M
6.6M
1.6M
-163.6M
-150.1M
-133.9M
-108.8M
92.6M
-80.4M
-53M
-28.3M
-131.2M
-117.3M
-62.5M
-683K
-32.1M
-42.1M
-19.7M
-9.1M
INVESTING ACTIVITIES
-138K
-298K
-2.8M
-464K
-575K
-196K
-555K
-1.8M
-3.6M
-16.6M
-1.4M
-526K
-564K
-1.3M
-595K
-2.6M
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(39K)
(105K)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
0.0
0.0
37K
0.0
0.0
0.0
8K
39K
105K
0.0
0.0
27K
29K
0.0
0.0
0.0
-138K
-298K
-2.8M
-464K
-575K
-196K
-547K
-1.7M
-3.5M
-16.6M
-1.4M
-499K
-535K
-1.3M
-595K
-2.6M
FINANCING ACTIVITIES
-139K
-353K
23.6M
223.6M
174.8M
0.0
0.0
39.8M
150.3M
128.8M
131.3M
117.3M
84.5M
26M
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
-4.4M
-2.8M
-169K
0.0
0.0
0.0
0.0
0.0
0.0
(0.0)
-353K
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
0.0
1.9M
21.5M
17.8M
15.5M
215K
228K
4.7M
17.8M
25.7M
9.5M
736K
-84K
142.2M
20.3M
11.7M
-139K
1.6M
45.1M
241.5M
190.3M
215K
228K
40M
165.4M
154.3M
140.8M
118.1M
84.5M
168.2M
20.3M
11.7M
CASH FLOW SUMMARY
-163.9M
-148.8M
-91.6M
132.2M
282.4M
-80.3M
-53.3M
10M
30.7M
20.4M
77M
116.9M
51.8M
124.9M
0.0
0.0
472.2M
621M
712.6M
580.4M
298.1M
378.4M
431.7M
421.7M
391M
370.6M
293.6M
176.7M
124.9M
0.0
0.0
0.0
308.4M
472.2M
621M
712.6M
580.4M
298.1M
378.4M
431.7M
421.7M
391M
370.6M
293.6M
176.7M
124.9M
0.0
0.0
-163.7M
-150.3M
-136.7M
-109.3M
92M
-80.6M
-53.5M
-30M
-134.8M
-133.9M
-63.8M
-1.2M
-32.7M
-43.4M
-20.3M
-11.7M

SEC Filings

PRTA - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
8-K

8-K 2026

N/A

May 15, 2026
May 14, 2026
2026
8-K

8-K 2026

N/A

May 07, 2026
May 07, 2026
2026
10-Q

10-Q 2026 Q1

Q1

May 07, 2026
March 31, 2026
2026
DEF 14A

DEF 14A 2026

N/A

March 27, 2026
May 14, 2026
2026
10-K

10-K 2025 FY

FY

February 27, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

February 27, 2026
February 27, 2026
2026
8-K

8-K 2026

N/A

February 19, 2026
February 19, 2026
2026
8-K

8-K 2025

N/A

December 12, 2025
December 10, 2025
2025
8-K

8-K 2025

N/A

November 19, 2025
November 19, 2025
2025
8-K

8-K 2025

N/A

November 06, 2025
November 06, 2025
2025
Showing 1 to 10 of 234 filings