Intellia Therapeutics, Inc.

Intellia Therapeutics, Inc.

NTLAยทNASDAQ

$13.02

-0.84%
HealthcareBiotechnology

Intellia Therapeutics, Inc., a genome editing company, focuses on the development of therapeutics. The company's in vivo programs include NTLA-2001, which is in Phase 1 clinical trial for the treatment of transthyretin amyloidosis; and NTLA-2002 for the treatment of hereditary angioedema, as well as other liver-focused programs comprising hemophilia A and hemophilia B, hyperoxaluria Type 1, and alpha-1 antitrypsin deficiency. Its ex vivo pipeline includes NTLA-5001 for the treatment of acute myeloid leukemia; and proprietary programs focused on developing engineered cell therapies to treat various oncological and autoimmune disorders. In addition, it offers tools comprising of Clustered, Regularly Interspaced Short Palindromic Repeats/CRISPR associated 9 (CRISPR/Cas9) system. Intellia Therapeutics, Inc. has license and collaboration agreements with Novartis Institutes for BioMedical Research, Inc. to engineer hematopoietic stem cells for the treatment of sickle cell disease; Regeneron Pharmaceuticals, Inc. to co-develop potential products for the treatment of hemophilia A and hemophilia B; Ospedale San Raffaele; and a strategic collaboration with SparingVision SAS to develop novel genomic medicines utilizing CRISPR/Cas9 technology for the treatment of ocular diseases. The company was formerly known as AZRN, Inc. Intellia Therapeutics, Inc. was incorporated in 2014 and is headquartered in Cambridge, Massachusetts.

At a Glance

Live Snapshot
Market Cap$1.46B
EPS-3.8100
P/E Ratio-3.42
Earnings Date07/30/2026
ntla

Intellia Therapeutics, Inc. Street Expectations Map

NTLA ยท NASDAQ

Wall Street analysts project that NTLA stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 26.29, with estimates ranging from a low of 13.00 to a high of 49.00.

Lowest Target
13.00
-0.15%
Consensus Target
26.29
101.92%
Highest Target
49.00
276.34%

The consensus 1-year price target stands at 26.29, with estimates ranging from a low of 13.00 to a high of 49.00.

Analyst Consensus Analysis

Upside Potential

+101.9%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

136.9% spread

High uncertainty. Very wide target spread indicates significant disagreement among analystsโ€”major valuation uncertainty or transformation underway.

Risk-Reward Profile

1799.00x

Favorable risk-reward. Potential upside significantly exceeds downside risk, offering asymmetric return profile attractive for risk-tolerant investors.

Analyst Conviction

Low

High uncertainty: Wide dispersion indicates analysts struggle to agree on valuationโ€”proceed with caution and independent analysis.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

ntla

Intellia Therapeutics, Inc. Forward Estimates of Revenue

NTLA ยท NASDAQ
Latest Revenue
67.67M
FY 2025
Avg Estimate
50.06M
FY 2026
Estimate Range
35.52M - 88.81M
Analyst Spread

Forward Growth Analysis

Projected Growth-26.0%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage17 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread106%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

ntla

Intellia Therapeutics, Inc. Forward Estimates of Net Income

NTLA ยท NASDAQ
Latest Net Income
-412.69M
FY 2025
Avg Estimate
-432.55M
FY 2026
Estimate Range
-452.67M - -194.57M
Analyst Spread

Forward Growth Analysis

Projected Growth-4.8%

Declining expectations indicate headwindsโ€”investigate whether temporary or structural issues.

Analyst Coverage17 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread60%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

ntla

Intellia Therapeutics, Inc. Forward Estimates of EPS

NTLA ยท NASDAQ
Latest EPS
-3.81
FY 2025
Avg Estimate
$-3.62
FY 2026
Estimate Range
$-4.58 - $-1.97
Analyst Spread

Forward Growth Analysis

Projected Growth+5.1%

Moderate growth expected, typical for mature businesses with stable market positions.

Analyst Coverage17 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread72%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

ntla

Intellia Therapeutics, Inc. Forward Estimates of EBIT

NTLA ยท NASDAQ
Latest EBIT
-412.69M
FY 2025
Avg Estimate
-50.06M
FY 2026
Estimate Range
-88.81M - -35.52M
Analyst Spread

Forward Growth Analysis

Projected Growth+87.9%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage17 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread106%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

ntla

Intellia Therapeutics, Inc. Forward Estimates of EBITDA

NTLA ยท NASDAQ
Latest EBITDA
-396.77M
FY 2025
Avg Estimate
-50.06M
FY 2026
Estimate Range
-88.81M - -35.52M
Analyst Spread

Forward Growth Analysis

Projected Growth+87.4%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage17 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread106%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

ntla

Intellia Therapeutics, Inc. Forward Estimates of SG&A Expense

NTLA ยท NASDAQ
Latest SG&A Expense
119.80M
FY 2025
Avg Estimate
100.43M
FY 2026
Estimate Range
71.26M - 178.16M
Analyst Spread

Forward Growth Analysis

Projected Growth-16.2%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage17 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread106%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

ntla

Intellia Therapeutics, Inc. Insider Positioning

NTLA ยท NASDAQ

During the last 12 months, insiders have purchased $2.41M and sold $1.47M worth of NTLA shares, resulting in $933K of net buying activity.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

150.0K

1.40M

Sold

135.6K

1.27M

Net Activity

+131K

+$131K

6-9 Months

Bought

0

0.00

Sold

1.9K

33.05K

Net Activity

-33K

-$33K

9-12 Months

Bought

100.0K

1.00M

Sold

14.1K

168.62K

Net Activity

+834K

+$834K

Top Buyers

1
CFE

Cohen Fred E

Director

150.0K sharesโ€ข1 transactions

$1.40M

2
CWJ

Chase William J

Director

100.0K sharesโ€ข1 transactions

$1.00M

Top Sellers

1
LJM

Leonard John M

Director, Officer: President And Ceo

84.1K sharesโ€ข2 transactions

$789K

2
DEJI

Dulac Edward J Iii

Officer: Evp, Chief Financial Officer

13.8K sharesโ€ข2 transactions

$163K

3
BJ

Basta James

Officer: Evp, General Counsel

11.6K sharesโ€ข2 transactions

$112K

4
LD

Lebwohl David

Officer: Evp, Chief Medical Officer

11.9K sharesโ€ข1 transactions

$110K

5
CE

Clark Eliana

Officer: Evp, Chief Technical Officer

11.1K sharesโ€ข3 transactions

$106K

Insider Activity Analysis

Net Insider Sentiment

Bullish

Moderately bullish with $933K net buying. Insiders show cautious optimism through measured share purchases.

Buy/Sell Ratio

1.63:1

Positive buy/sell ratio. Buying exceeds or matches selling, indicating net positive insider sentiment.

Insider Participation

High Selling

5 insider sellers vs. 2 buyers. Widespread selling across multiple insiders may signal concerns.