Nurix Therapeutics, Inc.

Nurix Therapeutics, Inc.

NRIX·NASDAQ

$15.48

-5.4%
HealthcareBiotechnology

Nurix Therapeutics, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of small molecule therapies for the treatment of cancer and immune disorders. The company develops NX-2127, an orally available Bruton's tyrosine kinase (BTK) degrader for the treatment of relapsed or refractory B-cell malignancies; NX-5948, an orally bioavailable BTK degrader for the treatment of relapsed or refractory B-cell malignancies and autoimmune diseases; and NX-1607, an orally available Casitas B-lineage lymphoma proto-oncogene-B (CBL-B) inhibitor for immuno-oncology indications. It also develops NX-0255, a CBL-B inhibitor for ex vivo use to enhance adoptive T-cell therapy; and DeTIL-0255 that is in the Phase 1 clinical trial for the treatment of gynecologic cancers, including ovarian, endometrial, and cervical cancer. The company has a strategic collaboration agreement with Gilead Sciences, Inc. for cancer and other challenging diseases patients; and Sanofi S.A. The company was formerly known as Nurix Inc. and changed its name to Nurix Therapeutics, Inc. in October 2018. The company was incorporated in 2009 and is headquartered in San Francisco, California.

At a Glance

Live Snapshot
Market Cap$1.34B
EPS-3.0500
P/E Ratio-5.08
Earnings Date07/08/2026
-47.26%
Return on Invested Capital
29%
3Y-10.0%
5Y+277.0%
10Y-42.0%
-49.09%
Return on Equity
34%
3Y-17.0%
5Y+230.0%
10Y-292.0%
-38.43%
Return on Assets
33%
3Y-11.0%
5Y+252.0%
10Y+85.0%
Nurix Therapeutics, Inc.

Nurix Therapeutics, Inc. Management Team

NRIX · NASDAQ
DJ

Dr. Jason Kantor Ph.D.

Chief Business Officer

DA

Dr. Arthur T. Sands M.D., Ph.D.

Chief Executive Officer, President & Director

Compensation

$1,061,146

Born 1962(Age 64)
MJ

Mr. Johannes Van Houte

Chief Financial Officer

Compensation

$733,135

Born 1966(Age 60)
male
DC

Dr. Christine Ring J.D., Ph.D.

Chief Legal Officer, Secretary & Chief Compliance Officer

Compensation

$733,137

Born 1965(Age 61)
DG

Dr. Gwenn M. Hansen Ph.D.

Chief Scientific Officer

Compensation

$750,513

Born 1971(Age 55)
DP

Dr. Pasit Phiasivongsa Ph.D.

Chief Technical Officer

DA

Dr. Arthur Weiss M.D., Ph.D.

Founder & Member of Scientific Advisory Board

DJ

Dr. John Kuriyan Ph.D.

Founder & Member of Scientific Advisory Board

RK

Rita Kwong

Senior Accounting Manager

MC

Mr. Christopher B. Phelps Ph.D.

Senior Vice President & Head of Early Drug Discovery

male
nrix

Nurix Therapeutics, Inc. Insider Positioning

NRIX · NASDAQ

During the last 12 months, insiders have purchased $626K and sold $2.48M worth of NRIX shares, resulting in $1.86M of net selling activity.

3 Months

Bought

0

0.00

Sold

52.1K

858.08K

Net Activity

-858K

-$858K

3-6 Months

Bought

0

0.00

Sold

33.3K

555.78K

Net Activity

-556K

-$556K

6-9 Months

Bought

50.0K

626.00K

Sold

54.7K

859.61K

Net Activity

-234K

-$234K

9-12 Months

Bought

0

0.00

Sold

17.9K

209.17K

Net Activity

-209K

-$209K

Top Buyers

1
DRD

Dansey Roger D

Director

50.0K shares1 transactions

$626K

Top Sellers

1
RC

Ring Christine

Officer: Chief Legal Officer

107.9K shares12 transactions

$1.77M

2
VHH

Van Houte Hans

Officer: Chief Financial Officer

38.6K shares7 transactions

$553K

3
HG

Hansen Gwenn

Officer: Chief Scientific Officer

11.6K shares3 transactions

$158K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $1.86M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.25:1

Weak buy/sell ratio. Selling significantly exceeds buying—monitor for potential fundamental concerns.

Recent Trend (3 Months)

$858K

Heavy recent selling activity. Recent insider sales notably exceed purchases—may warrant investigation into company developments.

Insider Participation

High Selling

3 insider sellers vs. 1 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.

SEC Filings

NRIX - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

March 27, 2026
May 15, 2026
2026
DEF 14A

DEF 14A 2025

N/A

March 28, 2025
May 19, 2025
2025
DEF 14A

DEF 14A 2024

N/A

March 27, 2024
May 20, 2024
2024
DEF 14A

DEF 14A 2023

N/A

March 24, 2023
May 04, 2023
2023
DEF 14A

DEF 14A 2022

N/A

March 25, 2022
May 05, 2022
2022
DEF 14A

DEF 14A 2021

N/A

March 25, 2021
May 06, 2021
2021
Showing 1 to 6 of 6 filings