Nurix Therapeutics, Inc.

Nurix Therapeutics, Inc.

NRIXยทNASDAQ

$15.81

-3.4%
HealthcareBiotechnology

Nurix Therapeutics, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of small molecule therapies for the treatment of cancer and immune disorders. The company develops NX-2127, an orally available Bruton's tyrosine kinase (BTK) degrader for the treatment of relapsed or refractory B-cell malignancies; NX-5948, an orally bioavailable BTK degrader for the treatment of relapsed or refractory B-cell malignancies and autoimmune diseases; and NX-1607, an orally available Casitas B-lineage lymphoma proto-oncogene-B (CBL-B) inhibitor for immuno-oncology indications. It also develops NX-0255, a CBL-B inhibitor for ex vivo use to enhance adoptive T-cell therapy; and DeTIL-0255 that is in the Phase 1 clinical trial for the treatment of gynecologic cancers, including ovarian, endometrial, and cervical cancer. The company has a strategic collaboration agreement with Gilead Sciences, Inc. for cancer and other challenging diseases patients; and Sanofi S.A. The company was formerly known as Nurix Inc. and changed its name to Nurix Therapeutics, Inc. in October 2018. The company was incorporated in 2009 and is headquartered in San Francisco, California.

At a Glance

Live Snapshot
Market Cap$1.37B
EPS-3.0500
P/E Ratio-5.18
Earnings Date07/08/2026
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Nurix Therapeutics, Inc. Street Expectations Map

NRIX ยท NASDAQ

Wall Street analysts project that NRIX stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 32.20, with estimates ranging from a low of 28.00 to a high of 36.00.

Lowest Target
28.00
77.14%
Consensus Target
32.20
103.71%
Highest Target
36.00
127.76%

The consensus 1-year price target stands at 32.20, with estimates ranging from a low of 28.00 to a high of 36.00.

Analyst Consensus Analysis

Upside Potential

+103.7%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

24.8% spread

Good consensus alignment. Moderate target spread reflects general agreement on value drivers with some variance in assumptions.

Analyst Conviction

Very High

Strong buy conviction: High upside with tight consensus suggests compelling investment opportunity backed by analyst confidence.

Market Sentiment Insight

Rare opportunity: Exceptional upside potential with strong analyst consensus creates a compelling setup. The combination of significant price target premium and tight agreement suggests high-conviction undervaluation that may attract institutional capital.

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Nurix Therapeutics, Inc. Forward Estimates of Revenue

NRIX ยท NASDAQ
Latest Revenue
83.98M
FY 2025
Avg Estimate
62.40M
FY 2026
Estimate Range
38.40M - 161.64M
Analyst Spread

Forward Growth Analysis

Projected Growth-25.7%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage13 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread197%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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Nurix Therapeutics, Inc. Forward Estimates of Net Income

NRIX ยท NASDAQ
Latest Net Income
-264.46M
FY 2025
Avg Estimate
-235.96M
FY 2026
Estimate Range
-319.39M - -152.54M
Analyst Spread

Forward Growth Analysis

Projected Growth+10.8%

Solid growth trajectory indicates healthy business performance and competitive positioning.

Analyst Coverage13 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread71%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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Nurix Therapeutics, Inc. Forward Estimates of EPS

NRIX ยท NASDAQ
Latest EPS
-3.05
FY 2025
Avg Estimate
$-3.31
FY 2026
Estimate Range
$-4.76 - $-2.27
Analyst Spread

Forward Growth Analysis

Projected Growth-8.4%

Declining expectations indicate headwindsโ€”investigate whether temporary or structural issues.

Analyst Coverage12 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread75%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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Nurix Therapeutics, Inc. Forward Estimates of EBIT

NRIX ยท NASDAQ
Latest EBIT
-263.70M
FY 2025
Avg Estimate
-62.40M
FY 2026
Estimate Range
-161.64M - -38.40M
Analyst Spread

Forward Growth Analysis

Projected Growth+76.3%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage13 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread197%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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Nurix Therapeutics, Inc. Forward Estimates of EBITDA

NRIX ยท NASDAQ
Latest EBITDA
-244.84M
FY 2025
Avg Estimate
-62.40M
FY 2026
Estimate Range
-161.64M - -38.40M
Analyst Spread

Forward Growth Analysis

Projected Growth+74.5%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage13 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread197%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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Nurix Therapeutics, Inc. Forward Estimates of SG&A Expense

NRIX ยท NASDAQ
Latest SG&A Expense
52.74M
FY 2025
Avg Estimate
54.25M
FY 2026
Estimate Range
33.39M - 140.54M
Analyst Spread

Forward Growth Analysis

Projected Growth+2.9%

Flat growth suggests market maturity or near-term challenges offsetting expansion efforts.

Analyst Coverage13 Analysts

Good analyst coverage ensures reliable estimates with diverse professional perspectives.

Estimate Spread197%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

High forecast uncertainty: Wide estimate range indicates analysts struggling to predict outcomesโ€”suggests elevated risk and potential volatility.

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Nurix Therapeutics, Inc. Insider Positioning

NRIX ยท NASDAQ

During the last 12 months, insiders have purchased $626K and sold $2.48M worth of NRIX shares, resulting in $1.86M of net selling activity.

3 Months

Bought

0

0.00

Sold

52.1K

858.08K

Net Activity

-858K

-$858K

3-6 Months

Bought

0

0.00

Sold

33.3K

555.78K

Net Activity

-556K

-$556K

6-9 Months

Bought

50.0K

626.00K

Sold

54.7K

859.61K

Net Activity

-234K

-$234K

9-12 Months

Bought

0

0.00

Sold

17.9K

209.17K

Net Activity

-209K

-$209K

Top Buyers

1
DRD

Dansey Roger D

Director

50.0K sharesโ€ข1 transactions

$626K

Top Sellers

1
RC

Ring Christine

Officer: Chief Legal Officer

107.9K sharesโ€ข12 transactions

$1.77M

2
VHH

Van Houte Hans

Officer: Chief Financial Officer

38.6K sharesโ€ข7 transactions

$553K

3
HG

Hansen Gwenn

Officer: Chief Scientific Officer

11.6K sharesโ€ข3 transactions

$158K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $1.86M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.25:1

Weak buy/sell ratio. Selling significantly exceeds buyingโ€”monitor for potential fundamental concerns.

Recent Trend (3 Months)

$858K

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

High Selling

3 insider sellers vs. 1 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.