Monopar Therapeutics Inc.

Monopar Therapeutics Inc.

MNPR·NASDAQ

$60.56

-1.1%
HealthcareBiotechnology

Monopar Therapeutics Inc., a clinical-stage biopharmaceutical company, engages in developing therapeutics for the treatment of cancer in the United States. Its lead product candidate in development is Validive, a clonidine hydrochloride mucobuccal tablet that is in Phase 2b/3 clinical trial for the prevention of chemoradiotherapy induced severe oral mucositis in patients with oropharyngeal cancer. The company also engages in developing Camsirubicin, an analog of doxorubicin, which is in Phase 1b clinical trial for the treatment of advanced soft tissue sarcoma; MNPR-101, a urokinase plasminogen activator receptor targeted antibody for the treatment of various cancers; MNPR-101 RIT, a radioimmunotherapeutic based on MNPR-101 for the potential treatment of cancer and severe COVID-19; and MNPR-202, an analog of camsirubicin to potentially treat doxorubicin-and camsirubicin-resistant cancers. Monopar Therapeutics Inc. has collaborations with the Grupo Español de Investigación en Sarcomas for the development of camsirubicin in patients with advanced soft tissue sarcoma; NorthStar Medical Radioisotopes, LLC to develop radio-immuno-therapeutics targeting severe COVID-19; and the Cancer Science Institute of Singapore to evaluate the activity of MNPR-202 and related analogs in various types of cancer. The company was incorporated in 2014 and is headquartered in Wilmette, Illinois.

At a Glance

Live Snapshot
Market Cap$405.70M
EPS-1.8500
P/E Ratio-32.74
Earnings Date08/06/2026
3Y+168693.0%
5Y+261603.0%
10Y+1021243.0%
3Y+1289988.0%
5Y-
10Y-
3Y+278570161.0%
5Y+1119101.0%
10Y+7253318.0%
MNPR

Monopar Therapeutics Inc. Cash Conversion Engine

MNPR · NASDAQ
Net Income-13.72B
Depreciation & Amortization-716.46M
Stock-Based Compensation4.84B
Change in Working Capital-2.61M
Others-2.60B
Capital Expenditures0.00
Free Cash Flow-12.20B

Cash Flow Quality Analysis

FCF Conversion Rate

89.0%

Strong cash conversion. Most reported earnings translate into actual cash flow, suggesting solid fundamentals.

FCF Growth Trend

-190422.0%

Significant FCF decline raises concerns. Urgent review needed of operational performance and capital allocation.

Working Capital Impact

-$2.61M

Minimal working capital impact on FCF. Changes in operating assets and liabilities well-managed.

Cash Flow Quality Insight

Working capital strain: Significant cash tied up in operations. Monitor receivables collection, inventory turns, and payment terms to optimize cash conversion cycle.

Monopar Therapeutics Inc. Cash Flow Statement

MNPR • NASDAQ

Monopar Therapeutics Inc. Cash Flow StatementDec 2025Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020Dec 2019Dec 2018Dec 2017Dec 2016Dec 2015
OPERATING ACTIVITIES
-13.7B
-15.6M
-8.4M
-10.5M
-9.1M
-6.3M
-4.2M
-3.2M
-16.6M
-1.2M
-687.3K
-716.5M
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
4.8B
1.1M
1.9M
1.6M
1.5M
1.3M
1M
529.3K
305.2K
0.0
0.0
-2.6B
4.6M
0.0
0.0
0.0
-122.4K
0.0
441.6K
13.5M
9.3K
-73.8K
-2.6M
3.5M
-1.4M
1.6M
317.8K
443.8K
196K
-188.2K
120.6K
-9K
51K
-12.2B
-6.4M
-7.9M
-7.2M
-7.3M
-4.7M
-3M
-2.9M
-2.6M
-1.2M
-636.3K
INVESTING ACTIVITIES
-87.2B
-15.3M
-7.9M
-4.9M
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
23.7B
985.7K
12.8M
0.0
0.0
0.0
0.0
0.0
0.0
0.0
0.0
-63.5B
-14.3M
(4.9M)
-4.9M
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
FINANCING ACTIVITIES
92.7M
59.4M
2.1M
109.3K
10.9M
8.2M
10.2M
0.0
4.7M
0.0
0.0
0.0
0.0
0.0
0.0
0.0
122.4K
0.0
0.0
0.0
0.0
0.0
-35M
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
91.5B
-104.1K
-47K
-76.5K
-45.8K
-115.6K
-874.8K
-206.3K
4.8M
0.0
3.4M
91.6B
59.3M
2M
32.9K
10.9M
8.2M
9.3M
-206.3K
9.5M
1.3M
3.4M
CASH FLOW SUMMARY
97.3M
494.0
-16.8K
-3.5K
4.6K
3.3K
-8.6K
-2.4K
0.0
0.0
0.0
16B
38.6M
-920.1K
-12.1M
3.6M
3.5M
6.3M
-2.9M
6.9M
67.9K
2.8M
45.8B
7.3M
8.2M
20.3M
16.7M
13.2M
6.9M
9.8M
2.9M
2.8M
-800K
61.8B
45.8M
7.3M
8.2M
20.3M
16.7M
13.2M
6.9M
9.8M
2.9M
2M
-12.2B
-6.4M
-7.9M
-7.2M
-7.3M
-4.7M
-3M
-2.9M
-2.6M
-1.2M
-636.3K

SEC Filings

MNPR - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
8-K

8-K 2026

N/A

May 29, 2026
May 29, 2026
2026
8-K

8-K 2026

N/A

May 19, 2026
May 19, 2026
2026
10-Q

10-Q 2026 Q1

Q1

May 14, 2026
March 31, 2026
2026
8-K

8-K 2026

N/A

May 14, 2026
May 14, 2026
2026
DEF 14A

DEF 14A 2026

N/A

April 30, 2026
June 22, 2026
2026
8-K

8-K 2026

N/A

April 20, 2026
April 19, 2026
2026
10-K/A

10-K/A 2025 FY (Amended)

FY

April 01, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

March 27, 2026
March 27, 2026
2026
10-K

10-K 2025 FY

FY

March 27, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

March 02, 2026
March 02, 2026
2026
Showing 1 to 10 of 171 filings