Monopar Therapeutics Inc.

Monopar Therapeutics Inc.

MNPR·NASDAQ

$60.56

-1.1%
HealthcareBiotechnology

Monopar Therapeutics Inc., a clinical-stage biopharmaceutical company, engages in developing therapeutics for the treatment of cancer in the United States. Its lead product candidate in development is Validive, a clonidine hydrochloride mucobuccal tablet that is in Phase 2b/3 clinical trial for the prevention of chemoradiotherapy induced severe oral mucositis in patients with oropharyngeal cancer. The company also engages in developing Camsirubicin, an analog of doxorubicin, which is in Phase 1b clinical trial for the treatment of advanced soft tissue sarcoma; MNPR-101, a urokinase plasminogen activator receptor targeted antibody for the treatment of various cancers; MNPR-101 RIT, a radioimmunotherapeutic based on MNPR-101 for the potential treatment of cancer and severe COVID-19; and MNPR-202, an analog of camsirubicin to potentially treat doxorubicin-and camsirubicin-resistant cancers. Monopar Therapeutics Inc. has collaborations with the Grupo Español de Investigación en Sarcomas for the development of camsirubicin in patients with advanced soft tissue sarcoma; NorthStar Medical Radioisotopes, LLC to develop radio-immuno-therapeutics targeting severe COVID-19; and the Cancer Science Institute of Singapore to evaluate the activity of MNPR-202 and related analogs in various types of cancer. The company was incorporated in 2014 and is headquartered in Wilmette, Illinois.

At a Glance

Live Snapshot
Market Cap$405.70M
EPS-1.8500
P/E Ratio-32.74
Earnings Date08/06/2026
-0.01%
Return on Invested Capital
-100%
3Y-100.0%
5Y-100.0%
10Y-100.0%
-0.01%
Return on Equity
-100%
3Y-100.0%
5Y-100.0%
10Y-100.0%
-0.01%
Return on Assets
-100%
3Y-100.0%
5Y-100.0%
10Y-100.0%
Monopar Therapeutics Inc.

Monopar Therapeutics Inc. Management Team

MNPR · NASDAQ
DP

Dr. Patrice P. Rioux M.D., Ph.D.

Acting Chief Medical Officer

Born 1951(Age 75)
MQ

Mr. Quan Anh Vu

Chief Financial Officer, Principal accounting officer & Principal financial officer

Born 1969(Age 57)
male
MA

Mr. Andrew J. Cittadine M.B.A.

Chief Operating Officer

Compensation

$542,544

Born 1972(Age 54)
male
DC

Dr. Christopher M. Starr Ph.D.

Co-Founder & Independent Executive Chairman of the Board

Compensation

$200,000

Born 1952(Age 74)
DC

Dr. Chandler D. Robinson M.B.A., M.D., M.Sc., MBA, MSc

Co-Founder, Chief Executive Officer, President & Director

Compensation

$1,144,480

Born 1984(Age 42)
mnpr

Monopar Therapeutics Inc. Insider Positioning

MNPR · NASDAQ

During the last 12 months, insiders have purchased $105K and sold $37.01M worth of MNPR shares, resulting in $36.91M of net selling activity.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

1.5K

104.92K

Sold

4.7K

312.50K

Net Activity

-208K

-$208K

6-9 Months

Bought

0

0.00

Sold

550.2K

35.00M

Net Activity

-35.0M

-$35.00M

9-12 Months

Bought

0

0.00

Sold

42.5K

1.70M

Net Activity

-1.7M

-$1.70M

Top Buyers

1
VQA

Vu Quan Anh

Officer: Chief Financial Officer

1.5K shares1 transactions

$105K

Top Sellers

1
TPL

Tactic Pharma Llc

10 Percent Owner

550.2K shares1 transactions

$35.00M

2
RC

Robinson Chandler

Director, Officer: Chief Executive Officer

16.8K shares1 transactions

$672K

3
SCM

Starr Christopher M

Director

16.8K shares1 transactions

$672K

4
TKR

Tsuchimoto Kim R

Director

8.9K shares1 transactions

$356K

5
KAJ

Klausner Arthur J

Director

4.7K shares1 transactions

$312K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $36.91M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Insider Participation

High Selling

5 insider sellers vs. 1 buyers. Widespread selling across multiple insiders may signal concerns.

SEC Filings

MNPR - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 30, 2026
June 22, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 30, 2025
June 17, 2025
2025
DEF 14A

DEF 14A 2024

N/A

July 22, 2024
August 05, 2024
2024
DEF 14A

DEF 14A 2023

N/A

April 28, 2023
June 27, 2023
2023
DEF 14A

DEF 14A 2022

N/A

April 29, 2022
June 28, 2022
2022
DEF 14A

DEF 14A 2021

N/A

April 30, 2021
June 30, 2021
2021
DEF 14A

DEF 14A 2020

N/A

April 29, 2020
June 11, 2020
2020
Showing 1 to 7 of 7 filings