MeiraGTx Holdings plc

MeiraGTx Holdings plc

MGTX·NASDAQ

$9.39

+1.6%
HealthcareBiotechnology

MeiraGTx Holdings plc, a clinical stage gene therapy company, focusing on developing treatments for patients with serious diseases. The company develops various therapies for ocular diseases, including inherited blindness, as well as Xerostomia following radiation treatment for head and neck cancers; degenerative diseases; neurodegenerative diseases, such as amyotrophic lateral sclerosis; and Parkinson's diseases. Its programs in clinical development include Phase 1/2 clinical stage programs in Achromatopsia, X-Linked Retinitis Pigmentosa, RPE65-deficiency, and radiation-induced Xerostomia, as well as Parkinson's program. The company also focuses on initiating a clinical program in xerostomia related to Sjogren's syndrome and have preclinical programs in neurodegenerative diseases. It has a research collaboration agreement with Janssen Pharmaceuticals, Inc. to develop regulatable gene therapy treatment using the company's proprietary riboswitch technology. MeiraGTx Holdings plc was incorporated in 2015 and is based in New York, New York.

At a Glance

Live Snapshot
Market Cap$869.60M
EPS-1.4200
P/E Ratio-6.61
Earnings Date08/06/2026
-70.92%
Return on Invested Capital
-8%
3Y+46.0%
5Y+254.0%
10Y-42.0%
1971.36%
Return on Equity
-1005%
3Y-1891.0%
5Y-8209.0%
10Y+1634.0%
-46.72%
Return on Assets
-15%
3Y+15.0%
5Y+193.0%
10Y-46.0%
MeiraGTx Holdings plc

MeiraGTx Holdings plc Management Team

MGTX · NASDAQ
DS

Dr. Stuart Naylor Ph.D.

Chief Development Officer

Compensation

$1,101,165

Born 1963(Age 63)
DA

Dr. Alexandria Forbes Ph.D.

Chief Executive Officer, President & Director

Compensation

$3,056,403

Born 1965(Age 61)
DR

Dr. Robert K. Zeldin M.D.

Chief Medical Officer

Compensation

$1,097,400

Born 1963(Age 63)
MR

Mr. Richard Brian Giroux B.A.

Chief Operating Officer & Chief Financial Officer

Compensation

$2,874,700

Born 1974(Age 52)
male
MR

Mr. Robert J. Wollin J.D.

General Counsel & Secretary

Born 1976(Age 50)
male
DM

Dr. Michel Michaelides M.D.

Head of Clinical Ophthalmology

DD

Dr. David Rubinstein Ph.D.

Senior Vice President of Business Development

MC

Ms. Christine Elise Sheehy

Senior Vice President of Global Integration

Born 1968(Age 58)
female
MT

Mr. Tim Randall

Senior Vice President of Risk & Internal Controls

male
mgtx

MeiraGTx Holdings plc Insider Positioning

MGTX · NASDAQ

During the last 12 months, insiders have sold $3.05M worth of MGTX shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

207.7K

1.86M

Net Activity

-1.9M

-$1.86M

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

0

0.00

Sold

71.5K

611.40K

Net Activity

-611K

-$611K

9-12 Months

Bought

0

0.00

Sold

71.5K

583.05K

Net Activity

-583K

-$583K

Top Buyers

No buying activity

Top Sellers

1
FA

Forbes Alexandria

Director, Officer: President & Ceo

219.0K shares4 transactions

$1.81M

2
GR

Giroux Richard

Officer: Cfo & Coo

104.0K shares3 transactions

$990K

3
NS

Naylor Stuart

Officer: Chief Dev. Officer

27.7K shares1 transactions

$259K

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $3.05M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$1.86M

Heavy recent selling activity. Recent insider sales notably exceed purchases—may warrant investigation into company developments.

Insider Participation

High Selling

3 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.

SEC Filings

MGTX - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 30, 2026
June 11, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 30, 2025
June 12, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 25, 2024
June 06, 2024
2024
DEF 14A

DEF 14A 2023

N/A

April 27, 2023
June 08, 2023
2023
DEF 14A

DEF 14A 2023

N/A

December 23, 2022
January 24, 2023
2023
DEF 14A

DEF 14A 2022

N/A

May 02, 2022
June 07, 2022
2022
DEF 14A

DEF 14A 2021

N/A

April 28, 2021
June 10, 2021
2021
DEF 14A

DEF 14A 2020

N/A

April 21, 2020
June 02, 2020
2020
DEF 14A

DEF 14A 2019

N/A

April 29, 2019
June 19, 2019
2019
Showing 1 to 9 of 9 filings