Seres Therapeutics, Inc.

Seres Therapeutics, Inc.

MCRBยทNASDAQ

$7.17

-5.3%
HealthcareBiotechnology

Seres Therapeutics, Inc., a microbiome therapeutics platform company, engages in developing bacterial consortia that are designed to functionally interact with host cells and tissues to treat disease. The company's lead product candidate is the SER-109, an oral microbiome therapeutic candidate that has completed Phase III clinical trial for the treatment of clostridium difficile infection (CDI). It is also developing SER-155, a cultivated bacteria microbiome drug, which is Phase Ib clinical trial to reduce incidences of gastrointestinal infections, bloodstream infections, and graft versus host diseases in immunocompromised patients receiving allogeneic hematopoietic stem cell transplantation and solid organ transplants. In addition, the company engages in the development of SER-287 and SER-301 that are in Phase Ib to treat ulcerative colitis; SER-401 for patients with metastatic melanoma; and SER-262 to treat Clostridioides difficile infection. It has license and collaboration agreements with Nestec Ltd. and Memorial Sloan Kettering Cancer Center. The company was formerly known as Seres Health, Inc. and changed its name to Seres Therapeutics, Inc. in May 2015. Seres Therapeutics, Inc. was incorporated in 2010 and is headquartered in Cambridge, Massachusetts.

At a Glance

Live Snapshot
Market Cap$69.43M
EPS0.6400
P/E Ratio11.20
Earnings Date08/05/2026
mcrb

Seres Therapeutics, Inc. Street Expectations Map

MCRB ยท NASDAQ

Wall Street analysts project that MCRB stock may decline over the coming 12 months. The consensus 1-year price target stands at 1.25, with estimates ranging from a low of 1.25 to a high of 1.25.

Lowest Target
1.25
-82.57%
Consensus Target
1.25
-82.57%
Highest Target
1.25
-82.57%

The consensus 1-year price target stands at 1.25, with estimates ranging from a low of 1.25 to a high of 1.25.

Analyst Consensus Analysis

Upside Potential

-82.6%

Significant downside risk. Stock trading well above analyst consensus suggests elevated valuation concerns and potential correction.

Analyst Agreement

0.0% spread

High analyst agreement. Narrow target range indicates strong consensus on valuation, suggesting clear investment thesis and predictable outlook.

Risk-Reward Profile

1.00x

Balanced risk-reward. Upside and downside potential relatively symmetric. Suitable for moderate risk tolerance with conviction in thesis.

Analyst Conviction

Low

Bearish or uncertain outlook. Limited upside or poor consensus suggests challenges ahead or fundamental concerns.

Market Sentiment Insight

Consensus overvaluation: Analysts agree the stock is richly valued with limited upside. Consider booking profits or defensive positioning unless you have contrarian conviction in unrecognized catalysts.

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Seres Therapeutics, Inc. Forward Estimates of Revenue

MCRB ยท NASDAQ
Latest Revenue
789.00K
FY 2025
Avg Estimate
716.00K
FY 2026
Estimate Range
716.00K - 716.00K
Analyst Spread

Forward Growth Analysis

Projected Growth-9.3%

Declining expectations indicate headwindsโ€”investigate whether temporary or structural issues.

Analyst Coverage1 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

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Seres Therapeutics, Inc. Forward Estimates of Net Income

MCRB ยท NASDAQ
Latest Net Income
5.70M
FY 2025
Avg Estimate
-81.51M
FY 2026
Estimate Range
-81.51M - -81.51M
Analyst Spread

Forward Growth Analysis

Projected Growth-1531.1%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage1 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Seres Therapeutics, Inc. Forward Estimates of EPS

MCRB ยท NASDAQ
Latest EPS
0.64
FY 2025
Avg Estimate
$-9.19
FY 2026
Estimate Range
$-9.19 - $-9.19
Analyst Spread

Forward Growth Analysis

Projected Growth-1535.9%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage1 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Seres Therapeutics, Inc. Forward Estimates of EBIT

MCRB ยท NASDAQ
Latest EBIT
-93.97M
FY 2025
Avg Estimate
224.48K
FY 2026
Estimate Range
224.48K - 224.48K
Analyst Spread

Forward Growth Analysis

Projected Growth+100.2%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage1 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Seres Therapeutics, Inc. Forward Estimates of EBITDA

MCRB ยท NASDAQ
Latest EBITDA
-89.84M
FY 2025
Avg Estimate
230.35K
FY 2026
Estimate Range
230.35K - 230.35K
Analyst Spread

Forward Growth Analysis

Projected Growth+100.3%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage1 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Seres Therapeutics, Inc. Forward Estimates of SG&A Expense

MCRB ยท NASDAQ
Latest SG&A Expense
39.16M
FY 2025
Avg Estimate
7.60M
FY 2026
Estimate Range
7.60M - 7.60M
Analyst Spread

Forward Growth Analysis

Projected Growth-80.6%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage1 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Seres Therapeutics, Inc. Insider Positioning

MCRB ยท NASDAQ

During the last 12 months, insiders have purchased $261K and sold $60K worth of MCRB shares, resulting in $201K of net buying activity.

3 Months

Bought

0

0.00

Sold

474

3.57K

Net Activity

-4K

-$4K

3-6 Months

Bought

0

0.00

Sold

501

4.24K

Net Activity

-4K

-$4K

6-9 Months

Bought

0

0.00

Sold

2.6K

44.84K

Net Activity

-45K

-$45K

9-12 Months

Bought

24.4K

261.04K

Sold

425

7.08K

Net Activity

+254K

+$254K

Top Buyers

1
BS

Berenson Stephen

Director

11.5K sharesโ€ข1 transactions

$123K

2
FC

Fraser Claire

Director

6.5K sharesโ€ข1 transactions

$69K

3
ADA

Ausiello Dennis A

Director

6.5K sharesโ€ข1 transactions

$69K

Top Sellers

1
HMR

Henn Matthew R

Officer: See Remarks

1.5K sharesโ€ข4 transactions

$24K

2
YTL

Young Teresa L.

Officer: See Remarks

1.2K sharesโ€ข3 transactions

$20K

3
SED

Shaff Eric D.

Director

952 sharesโ€ข4 transactions

$12K

4
DT

Desrosier Thomas

Officer: See Remarks

309 sharesโ€ข4 transactions

$4K

5
BK

Brady Kelly

Officer: See Remarks

59 sharesโ€ข1 transactions

$444

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $201K net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

4.37:1

Exceptional buy/sell ratio. Buying dramatically outweighs sellingโ€”one of the strongest possible insider signals.

Recent Trend (3 Months)

$4K

Heavy recent selling activity. Recent insider sales notably exceed purchasesโ€”may warrant investigation into company developments.

Insider Participation

Moderate Selling

5 insider sellers vs. 3 buyers. More insiders selling than buying suggests cautious or negative sentiment.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.