MB

MBX Biosciences, Inc. Common Stock

MBX·NASDAQ

$30.05

-2.1%
HealthcareBiotechnology

MBX Biosciences, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery and development of precision peptide therapies for the treatment of endocrine and metabolic disorders. Its lead product candidate is MBX 2109, a parathyroid hormone peptide prodrug, which is in Phase 2 clinical trial designed as a potential long-acting hormone replacement therapy for the treatment of chronic hypoparathyroidism. The company is also developing MBX 1416, a long-acting glucagon-like peptide-1 (GLP-1) receptor antagonist that is in Phase 1 clinical trial designed as a potential therapy for post-bariatric hypoglycemia, a chronic complication of bariatric surgery. In addition, it is developing MBX 4291, a lead obesity product candidate, which is in investigational new drug-enabling studies designed as a long-acting and highly potent GLP-1 and glucose-dependent insulinotropic polypeptide receptor co-agonist prodrug for treating obesity and co-morbidities. The company was founded in 2018 and is based in Carmel, Indiana.

At a Glance

Live Snapshot
Market Cap$1.01B
EPS-2.3800
P/E Ratio-12.63
Earnings Date08/06/2026
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MBX Biosciences, Inc. Common Stock Street Expectations Map

MBX · NASDAQ

Wall Street analysts project that MBX stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 60.33, with estimates ranging from a low of 18.00 to a high of 88.00.

Lowest Target
18.00
-40.10%
Consensus Target
60.33
100.77%
Highest Target
88.00
192.85%

The consensus 1-year price target stands at 60.33, with estimates ranging from a low of 18.00 to a high of 88.00.

Analyst Consensus Analysis

Upside Potential

+100.8%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

116.0% spread

High uncertainty. Very wide target spread indicates significant disagreement among analysts—major valuation uncertainty or transformation underway.

Risk-Reward Profile

4.81x

Favorable risk-reward. Potential upside significantly exceeds downside risk, offering asymmetric return profile attractive for risk-tolerant investors.

Analyst Conviction

Low

High uncertainty: Wide dispersion indicates analysts struggle to agree on valuation—proceed with caution and independent analysis.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

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MBX Biosciences, Inc. Common Stock Forward Estimates of Revenue

MBX · NASDAQ
Latest Revenue
0.00
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

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MBX Biosciences, Inc. Common Stock Forward Estimates of Net Income

MBX · NASDAQ
Latest Net Income
-86.97M
FY 2025
Avg Estimate
-105.73M
FY 2026
Estimate Range
-115.99M - -95.46M
Analyst Spread

Forward Growth Analysis

Projected Growth-21.6%

Significant contraction projected—major business challenges or industry disruption likely.

Estimate Spread19%

Reasonable estimate spread indicates general agreement with normal forecast variance.

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

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MBX Biosciences, Inc. Common Stock Forward Estimates of EPS

MBX · NASDAQ
Latest EPS
-2.38
FY 2025
Avg Estimate
$-2.80
FY 2026
Estimate Range
$-3.18 - $-2.61
Analyst Spread

Forward Growth Analysis

Projected Growth-17.7%

Significant contraction projected—major business challenges or industry disruption likely.

Analyst Coverage8 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread20%

Moderate uncertainty in forecasts—typical for companies with evolving business models.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

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MBX Biosciences, Inc. Common Stock Forward Estimates of EBIT

MBX · NASDAQ
Latest EBIT
-98.06M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

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MBX Biosciences, Inc. Common Stock Forward Estimates of EBITDA

MBX · NASDAQ
Latest EBITDA
-98.06M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth+100.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

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MBX Biosciences, Inc. Common Stock Forward Estimates of SG&A Expense

MBX · NASDAQ
Latest SG&A Expense
18.90M
FY 2025
Avg Estimate
0.00
FY 2026
Estimate Range
0.00 - 0.00
Analyst Spread

Forward Growth Analysis

Projected Growth-100.0%

Significant contraction projected—major business challenges or industry disruption likely.

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

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MBX Biosciences, Inc. Common Stock Insider Positioning

MBX · NASDAQ

During the last 12 months, insiders have purchased $16.13M and sold $2.14M worth of MBX shares, resulting in $14.00M of net buying activity.

3 Months

Bought

18.5K

525.66K

Sold

55.8K

2.14M

Net Activity

-1.6M

-$1.61M

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

989.5K

15.61M

Sold

0

0.00

Net Activity

+15.6M

+$15.61M

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

1
HPJ

Heron Patrick J

Director, 10 Percent Owner:

666.7K shares1 transactions

$12.00M

2
HSL

Hoerter Steven L.

Director

120.0K shares2 transactions

$2.74M

3
HPK

Hawryluk P. Kent

Director, Officer: President & Ceo

221.4K shares3 transactions

$1.39M

Top Sellers

1
AS

Azoulay Salomon

Officer: Chief Medical Officer

55.2K shares2 transactions

$2.12M

2
HPK

Hawryluk P. Kent

Director, Officer: President & Ceo

607 shares1 transactions

$18K

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $14.00M net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

7.55:1

Exceptional buy/sell ratio. Buying dramatically outweighs selling—one of the strongest possible insider signals.

Recent Trend (3 Months)

$1.61M

Heavy recent selling activity. Recent insider sales notably exceed purchases—may warrant investigation into company developments.

Insider Participation

Moderate Buying

3 insider buyers vs. 2 sellers. More insiders buying than selling indicates positive sentiment.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.