Lexicon Pharmaceuticals, Inc.

Lexicon Pharmaceuticals, Inc.

LXRXยทNASDAQ

$1.85

-2.1%
HealthcareBiotechnology

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of pharmaceutical products. Its orally-delivered small molecule drug candidates under development comprise Sotagliflozin that completed Phase III clinical trials for the for the treatment of heart failure and type 1 diabetes; and LX9211, which is in Phase II clinical development for the treatment of neuropathic pain. The company has strategic collaboration and license agreements with Bristol-Myers Squibb Company, and Genentech, Inc. Lexicon Pharmaceuticals, Inc. was incorporated in 1995 and is headquartered in The Woodlands, Texas.

At a Glance

Live Snapshot
Market Cap$821.76M
EPS-0.1400
P/E Ratio-13.21
Earnings Date07/30/2026
-28.71%
Return on Invested Capital
-63%
3Y-51.0%
5Y+2.0%
10Y-40.0%
-46.81%
Return on Equity
-66%
3Y-46.0%
5Y+25.0%
10Y-48.0%
-27.21%
Return on Assets
-59%
3Y-48.0%
5Y-5.0%
10Y-8.0%
Lexicon Pharmaceuticals, Inc.

Lexicon Pharmaceuticals, Inc. Management Team

LXRX ยท NASDAQ
DM

Dr. Michael S. Exton Ph.D.

Chief Executive Officer & Director

Compensation

$830,545

Born 1970(Age 56)
DA

Dr. Alan J. Main Ph.D.

Executive Vice President of Innovation & Chemical Sciences

Compensation

$595,452

Born 1954(Age 72)
MS

Mr. Scott M. Coiante

Senior Vice President & Chief Financial Officer

Born 1967(Age 59)
male
DC

Dr. Craig B. Granowitz M.D., Ph.D.

Senior Vice President & Chief Medical Officer

Compensation

$717,078

Born 1965(Age 61)
ML

Ms. Lisa M. DeFrancesco

Senior Vice President of Investor Relations & Corporate Communications

Born 1980(Age 46)
female
MB

Mr. Brian T. Crum

Senior Vice President, General Counsel & Secretary

Compensation

$616,116

Born 1973(Age 53)
male
MD

Mr. Dixon Terry

Vice President of Compliance

male
MK

Ms. Kristen L. Alexander

Vice President of Finance & Accounting

Compensation

$379,807

Born 1968(Age 58)
female
MC

Ms. Carrie Siragusa

Vice President of Marketing

female
MD

Ms. Desiree Gendron

Vice President of Sales & Training

female
lxrx

Lexicon Pharmaceuticals, Inc. Insider Positioning

LXRX ยท NASDAQ

During the last 12 months, insiders have purchased $2.72M worth of LXRX shares, with no selling activity reported.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

2.1M

2.72M

Sold

0

0.00

Net Activity

+2.7M

+$2.72M

6-9 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

1
IGML

Invus Global Management, Llc

Director, 10 Percent Owner:

1.5M sharesโ€ข1 transactions

$2.00M

2
DR

Debbane Raymond

Director

520.5K sharesโ€ข7 transactions

$723K

Top Sellers

No selling activity

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $2.72M net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

โˆž:1

Perfect buy/sell ratio. Only buying activity with zero sellingโ€”the most bullish possible insider signal.

Insider Participation

High Buying

2 insider buyers vs. 0 sellers. Broad-based buying across management team suggests widespread confidence.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.

SEC Filings

LXRX - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

March 16, 2026
March 16, 2026
2026
DEF 14A

DEF 14A 2025

N/A

April 22, 2025
April 22, 2025
2025
DEF 14A

DEF 14A 2024

N/A

March 26, 2024
March 25, 2024
2024
DEF 14A

DEF 14A 2023

N/A

March 17, 2023
March 16, 2023
2023
DEF 14A

DEF 14A 2022

N/A

April 08, 2022
April 07, 2022
2022
DEF 14A

DEF 14A 2021

N/A

March 19, 2021
March 19, 2021
2021
DEF 14A

DEF 14A 2020

N/A

March 13, 2020
March 13, 2020
2020
DEF 14A

DEF 14A 2018

N/A

March 15, 2019
December 31, 2018
2018
DEF 14A

DEF 14A 2018

N/A

March 16, 2018
March 16, 2018
2018
DEF 14A

DEF 14A 2017

N/A

March 17, 2017
March 17, 2017
2017
Showing 1 to 10 of 28 filings