Lexicon Pharmaceuticals, Inc.

Lexicon Pharmaceuticals, Inc.

LXRXยทNASDAQ

$1.85

-2.1%
HealthcareBiotechnology

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of pharmaceutical products. Its orally-delivered small molecule drug candidates under development comprise Sotagliflozin that completed Phase III clinical trials for the for the treatment of heart failure and type 1 diabetes; and LX9211, which is in Phase II clinical development for the treatment of neuropathic pain. The company has strategic collaboration and license agreements with Bristol-Myers Squibb Company, and Genentech, Inc. Lexicon Pharmaceuticals, Inc. was incorporated in 1995 and is headquartered in The Woodlands, Texas.

At a Glance

Live Snapshot
Market Cap$821.76M
EPS-0.1400
P/E Ratio-13.21
Earnings Date07/30/2026
lxrx

Lexicon Pharmaceuticals, Inc. Street Expectations Map

LXRX ยท NASDAQ

Wall Street analysts project that LXRX stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 6.00, with estimates ranging from a low of 6.00 to a high of 6.00.

Lowest Target
6.00
224.32%
Consensus Target
6.00
224.32%
Highest Target
6.00
224.32%

The consensus 1-year price target stands at 6.00, with estimates ranging from a low of 6.00 to a high of 6.00.

Analyst Consensus Analysis

Upside Potential

+224.3%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

0.0% spread

High analyst agreement. Narrow target range indicates strong consensus on valuation, suggesting clear investment thesis and predictable outlook.

Analyst Conviction

Very High

Strong buy conviction: High upside with tight consensus suggests compelling investment opportunity backed by analyst confidence.

Market Sentiment Insight

Rare opportunity: Exceptional upside potential with strong analyst consensus creates a compelling setup. The combination of significant price target premium and tight agreement suggests high-conviction undervaluation that may attract institutional capital.

lxrx

Lexicon Pharmaceuticals, Inc. Forward Estimates of Revenue

LXRX ยท NASDAQ
Latest Revenue
49.80M
FY 2025
Avg Estimate
14.96M
FY 2026
Estimate Range
7.48M - 22.44M
Analyst Spread

Forward Growth Analysis

Projected Growth-70.0%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread100%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

lxrx

Lexicon Pharmaceuticals, Inc. Forward Estimates of Net Income

LXRX ยท NASDAQ
Latest Net Income
-50.34M
FY 2025
Avg Estimate
-77.88M
FY 2026
Estimate Range
-97.73M - -58.03M
Analyst Spread

Forward Growth Analysis

Projected Growth-54.7%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread51%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

lxrx

Lexicon Pharmaceuticals, Inc. Forward Estimates of EPS

LXRX ยท NASDAQ
Latest EPS
-0.14
FY 2025
Avg Estimate
$-0.26
FY 2026
Estimate Range
$-0.31 - $-0.18
Analyst Spread

Forward Growth Analysis

Projected Growth-84.0%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread48%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

lxrx

Lexicon Pharmaceuticals, Inc. Forward Estimates of EBIT

LXRX ยท NASDAQ
Latest EBIT
-48.91M
FY 2025
Avg Estimate
-14.96M
FY 2026
Estimate Range
-22.44M - -7.48M
Analyst Spread

Forward Growth Analysis

Projected Growth+69.4%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread100%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

lxrx

Lexicon Pharmaceuticals, Inc. Forward Estimates of EBITDA

LXRX ยท NASDAQ
Latest EBITDA
-48.29M
FY 2025
Avg Estimate
-14.96M
FY 2026
Estimate Range
-22.44M - -7.48M
Analyst Spread

Forward Growth Analysis

Projected Growth+69.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread100%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

lxrx

Lexicon Pharmaceuticals, Inc. Forward Estimates of SG&A Expense

LXRX ยท NASDAQ
Latest SG&A Expense
37.32M
FY 2025
Avg Estimate
18.59M
FY 2026
Estimate Range
9.30M - 27.89M
Analyst Spread

Forward Growth Analysis

Projected Growth-50.2%

Significant contraction projectedโ€”major business challenges or industry disruption likely.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread100%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

lxrx

Lexicon Pharmaceuticals, Inc. Insider Positioning

LXRX ยท NASDAQ

During the last 12 months, insiders have purchased $2.72M worth of LXRX shares, with no selling activity reported.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

2.1M

2.72M

Sold

0

0.00

Net Activity

+2.7M

+$2.72M

6-9 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

9-12 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

Top Buyers

1
IGML

Invus Global Management, Llc

Director, 10 Percent Owner:

1.5M sharesโ€ข1 transactions

$2.00M

2
DR

Debbane Raymond

Director

520.5K sharesโ€ข7 transactions

$723K

Top Sellers

No selling activity

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $2.72M net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

โˆž:1

Perfect buy/sell ratio. Only buying activity with zero sellingโ€”the most bullish possible insider signal.

Insider Participation

High Buying

2 insider buyers vs. 0 sellers. Broad-based buying across management team suggests widespread confidence.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.