Lexicon Pharmaceuticals, Inc.

Lexicon Pharmaceuticals, Inc.

LXRXยทNASDAQ

$1.94

+2.4%
HealthcareBiotechnology

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of pharmaceutical products. Its orally-delivered small molecule drug candidates under development comprise Sotagliflozin that completed Phase III clinical trials for the for the treatment of heart failure and type 1 diabetes; and LX9211, which is in Phase II clinical development for the treatment of neuropathic pain. The company has strategic collaboration and license agreements with Bristol-Myers Squibb Company, and Genentech, Inc. Lexicon Pharmaceuticals, Inc. was incorporated in 1995 and is headquartered in The Woodlands, Texas.

At a Glance

Live Snapshot
Market Cap$859.52M
EPS-0.1400
P/E Ratio-13.82
Earnings Date07/30/2026
3Y+35729.0%
5Y+108.0%
10Y-40.0%
3Y-51.0%
5Y-14.0%
10Y-64.0%
3Y-24.0%
5Y-53.0%
10Y-61.0%
Lexicon Pharmaceuticals, Inc.

Lexicon Pharmaceuticals, Inc. Profit Bridge

LXRX ยท NASDAQ
Revenue49.80M
Cost of Goods Sold (274.00K)
Gross Profit49.53M
Operating Expenses (98.44M)
Operating Income-48.91M
Interest Expense (8.34M)
Other Income/Expense-1.43M
Pretax Income-50.34M
Income Tax (0.00)
Net Income-50.34M
Net Income
-50.34M

Profitability Analysis

Gross Margin

99.4%

Exceptional pricing power and cost management. The company retains over half of revenue after direct costs.

Operating Margin

-98.2%

Operating losses indicate the core business is unprofitable. Requires restructuring or revenue growth.

Net Profit Margin

-101.1%

Net losses indicate the company is burning cash. Sustainability depends on path to profitability.

Profitability Insight

Margin squeeze alert: Healthy gross margins but weak operating margins suggest excessive operating expenses. Cost optimization could unlock significant value.

Lexicon Pharmaceuticals, Inc. Income Statement

LXRX โ€ข NASDAQ

Lexicon Pharmaceuticals, Inc. Income StatementDec 2025Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020Dec 2019Dec 2018Dec 2017Dec 2016Dec 2015Dec 2014Dec 2013Dec 2012Dec 2011Dec 2010Dec 2009Dec 2008Dec 2007Dec 2006
REVENUE
49.8M
31.1M
1.2M
139K
298K
24M
322.1M
63.2M
90.3M
83.3M
130M
22.9M
2.2M
1.1M
1.8M
4.9M
10.7M
32.3M
50.1M
72.8M
GROSS PROFIT
(274K)
(616K)
(59M)
(52.5M)
(55M)
(1.9M)
(3.2M)
(2.5M)
(1.9M)
(164M)
(95.2M)
(89.3M)
(89.7M)
(82.6M)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
49.5M
30.5M
-57.8M
-52.4M
-54.7M
22.1M
318.8M
60.7M
88.4M
-80.6M
34.8M
-66.4M
-87.5M
-81.5M
1.8M
4.9M
10.7M
32.3M
50.1M
72.8M
OPERATING INCOME
(98.4M)
(227.6M)
(114M)
(48.4M)
(32.3M)
(69.9M)
(177.4M)
(164M)
(223M)
(221.2M)
(119M)
(108.7M)
(106.8M)
(99.6M)
(115.9M)
(100.6M)
(100.7M)
(128.9M)
(125.1M)
(128M)
(37.3M)
(131.9M)
(0.0)
(0.0)
(0.0)
(47.2M)
(56.8M)
(63.8M)
(66.2M)
(43M)
(23.8M)
(19.4M)
(17.1M)
(17M)
(17.4M)
(22.6M)
(19.4M)
(20.3M)
(20.7M)
(21.3M)
(61.1M)
(84.5M)
(58.9M)
(52.8M)
(55M)
(153.6M)
(91.9M)
(100.2M)
(156.8M)
(178.2M)
(95.2M)
(89.3M)
(89.7M)
(82.6M)
(91.8M)
(75.4M)
(81.2M)
(108.6M)
(104.3M)
(106.7M)
-48.9M
-197.1M
-171.8M
-100.8M
-87.1M
-47.8M
141.4M
-103.3M
-136.7M
-137.2M
1.5M
-100.4M
-102.4M
-108.4M
-114.1M
-95.7M
-90M
-96.5M
-75M
-55.2M
PRE-TAX INCOME
(8.3M)
(15.6M)
(13.1M)
(2.8M)
(802K)
(14.5M)
(20.7M)
(20.8M)
(7M)
(6.6M)
(6.7M)
(2.3M)
(2M)
(2.1M)
(2.5M)
(2.7M)
(3M)
(2.7M)
(2.8M)
(3.3M)
-1.4M
-3.3M
-5.4M
-1.2M
-668K
-11.8M
-17.3M
-17.3M
-5M
-4.3M
-6.2M
2K
-1.8M
-1.8M
-2.3M
-2.2M
-2.1M
3.1M
4.5M
400K
(0.0)
(11.2M)
(55.1M)
-4.4M
-22.7M
-131M
(28.6M)
(0.0)
(2M)
(2.3M)
(572K)
(2.3M)
(59K)
(105K)
(24.1M)
(2.7M)
(0.0)
(0.0)
(0.0)
(0.0)
-1.4M
-3.3M
-5.4M
-1.2M
-668K
-10.8M
-17.3M
-17.3M
-5M
-4.3M
-6.2M
2K
-1.8M
-1.8M
-2.1M
-6.1M
-3.5M
-349K
3.7M
801K
-50.3M
-200.4M
-177.1M
-101.9M
-87.8M
-58.6M
124.1M
-120.5M
-141.7M
-141.4M
-4.7M
-100.4M
-104.1M
-110.2M
-116.2M
-101.8M
-93.4M
-96.9M
-71.2M
54.4M
NET INCOME
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
(0.0)
-6M
(0.0)
-12.7M
(4.5M)
(0.0)
-70K
-833K
(0.0)
(0.0)
-26K
-102K
(0.0)
-16.2M
-119K
-50.3M
-200.4M
-177.1M
-101.9M
-87.8M
-58.6M
130.1M
-120.5M
-129.1M
-141.4M
-4.7M
-100.3M
-104.1M
-110.2M
-116.2M
-101.8M
-82.8M
-76.9M
-58.8M
-54.3M

SEC Filings

LXRX - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
8-K

8-K 2026

N/A

May 07, 2026
May 07, 2026
2026
10-Q

10-Q 2026 Q1

Q1

May 07, 2026
March 31, 2026
2026
8-K

8-K 2026

N/A

May 06, 2026
May 04, 2026
2026
8-K

8-K 2026

N/A

April 30, 2026
April 30, 2026
2026
DEF 14A

DEF 14A 2026

N/A

March 16, 2026
March 16, 2026
2026
10-K

10-K 2025 FY

FY

March 05, 2026
December 31, 2025
2025
8-K

8-K 2026

N/A

March 05, 2026
March 05, 2026
2026
8-K

8-K 2026

N/A

February 02, 2026
January 29, 2026
2026
8-K

8-K 2026

N/A

January 29, 2026
January 29, 2026
2026
8-K

8-K 2025

N/A

November 10, 2025
November 06, 2025
2025
Showing 1 to 10 of 421 filings