Werewolf Therapeutics, Inc.

Werewolf Therapeutics, Inc.

HOWLยทNASDAQ

$1.04

-3.7%
HealthcareBiotechnology

Werewolf Therapeutics, Inc., a biopharmaceutical company, develops therapeutics engineered to stimulate the body's immune system for the treatment of cancer. The company, through its proprietary PREDATOR platform, designs conditionally activated molecules that stimulate adaptive and innate immunity for addressing the limitations of conventional proinflammatory immune therapies. Its lead product candidates are WTX-124, a conditionally activated Interleukin-2 INDUKINE molecule for the treatment of advanced solid tumors; and WTX-330, a conditionally activated Interleukin-12 INDUKINE molecule for the treatment of relapsed or refractory advanced or metastatic solid tumors or lymphoma. The company is also developing WTX-613, a conditionally activated interferon alpha INDUKINE molecule for the treatment of solid tumors and hematologic malignancies. Werewolf Therapeutics, Inc. was incorporated in 2017 and is headquartered in Cambridge, Massachusetts.

At a Glance

Live Snapshot
Market Cap$50.48M
EPS-1.3200
P/E Ratio-0.48
Earnings Date05/07/2026
-173.37%
Return on Invested Capital
167%
3Y+328.0%
5Y+620.0%
10Y+253.0%
-245.20%
Return on Equity
155%
3Y+457.0%
5Y-951.0%
10Y-642.0%
-87.64%
Return on Assets
58%
3Y+161.0%
5Y+466.0%
10Y+73.0%
Werewolf Therapeutics, Inc.

Werewolf Therapeutics, Inc. Management Team

HOWL ยท NASDAQ
MS

Mr. Steven H. Bloom R.Ph.

Chief Business Officer

Born 1961(Age 65)
male
MT

Mr. Timothy W. Trost CPA

Chief Financial Officer, Treasurer & Assistant Secretary

Compensation

$678,675

Born 1958(Age 68)
male
DR

Dr. Randi Isaacs M.D.

Chief Medical Officer

Compensation

$722,845

Born 1956(Age 70)
DC

Dr. Chulani Karunatilake Ph.D.

Chief Technology Officer

Compensation

$343,431

Born 1959(Age 67)
DD

Dr. Daniel J. Hicklin Ph.D.

Founder, Chief Executive Officer, President, Secretary & Director

Compensation

$985,732

Born 1964(Age 62)
DW

Dr. William Winston Ph.D.

Senior Vice President of Research

howl

Werewolf Therapeutics, Inc. Insider Positioning

HOWL ยท NASDAQ

During the last 12 months, insiders have purchased $231K and sold $6.52M worth of HOWL shares, resulting in $6.29M of net selling activity.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

0

0.00

Sold

891.9K

635.04K

Net Activity

-635K

-$635K

6-9 Months

Bought

0

0.00

Sold

5.1M

5.89M

Net Activity

-5.9M

-$5.89M

9-12 Months

Bought

179.4K

230.83K

Sold

0

0.00

Net Activity

+231K

+$231K

Top Buyers

1
MB

Morrison Briggs

Director

27.0K sharesโ€ข1 transactions

$35K

2
LA

Lazarus Alon

Director

27.0K sharesโ€ข1 transactions

$35K

3
CM

Chatterjee Meeta

Director

27.0K sharesโ€ข1 transactions

$35K

4
EL

Evnin Luke

Director

27.0K sharesโ€ข1 transactions

$35K

5
SMA

Sherman Michael A.

Director

27.0K sharesโ€ข1 transactions

$35K

Top Sellers

1
MB2L

Mpm Bioventures 2014, L.P.

Other: Former 10% Owner

1.9M sharesโ€ข28 transactions

$2.22M

2
GA

Gadicke Ansbert

Other: Former 10% Owner

1.9M sharesโ€ข28 transactions

$2.22M

3
EL

Evnin Luke

Director

2.1M sharesโ€ข55 transactions

$2.08M

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $6.29M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.04:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Insider Participation

Moderate Buying

5 insider buyers vs. 3 sellers. More insiders buying than selling indicates positive sentiment.

SEC Filings

HOWL - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2025

N/A

April 28, 2025
June 12, 2025
2025
DEF 14A

DEF 14A 2024

N/A

April 12, 2024
May 24, 2024
2024
DEF 14A

DEF 14A 2023

N/A

April 27, 2023
June 21, 2023
2023
DEF 14A

DEF 14A 2022

N/A

April 22, 2022
June 01, 2022
2022
Showing 1 to 4 of 4 filings