Werewolf Therapeutics, Inc.

Werewolf Therapeutics, Inc.

HOWLยทNASDAQ

$1.04

-3.7%
HealthcareBiotechnology

Werewolf Therapeutics, Inc., a biopharmaceutical company, develops therapeutics engineered to stimulate the body's immune system for the treatment of cancer. The company, through its proprietary PREDATOR platform, designs conditionally activated molecules that stimulate adaptive and innate immunity for addressing the limitations of conventional proinflammatory immune therapies. Its lead product candidates are WTX-124, a conditionally activated Interleukin-2 INDUKINE molecule for the treatment of advanced solid tumors; and WTX-330, a conditionally activated Interleukin-12 INDUKINE molecule for the treatment of relapsed or refractory advanced or metastatic solid tumors or lymphoma. The company is also developing WTX-613, a conditionally activated interferon alpha INDUKINE molecule for the treatment of solid tumors and hematologic malignancies. Werewolf Therapeutics, Inc. was incorporated in 2017 and is headquartered in Cambridge, Massachusetts.

At a Glance

Live Snapshot
Market Cap$50.48M
EPS-1.3200
P/E Ratio-0.48
Earnings Date05/07/2026
howl

Werewolf Therapeutics, Inc. Street Expectations Map

HOWL ยท NASDAQ

Wall Street analysts project that HOWL stock may see slight declines over the coming 12 months. The consensus 1-year price target stands at 1.00, with estimates ranging from a low of 1.00 to a high of 1.00.

Lowest Target
1.00
-3.85%
Consensus Target
1.00
-3.85%
Highest Target
1.00
-3.85%

The consensus 1-year price target stands at 1.00, with estimates ranging from a low of 1.00 to a high of 1.00.

Analyst Consensus Analysis

Upside Potential

-3.9%

Fair value territory. Stock trading near consensus target suggests limited near-term catalysts. Focus on fundamental developments.

Analyst Agreement

0.0% spread

High analyst agreement. Narrow target range indicates strong consensus on valuation, suggesting clear investment thesis and predictable outlook.

Risk-Reward Profile

1.00x

Balanced risk-reward. Upside and downside potential relatively symmetric. Suitable for moderate risk tolerance with conviction in thesis.

Analyst Conviction

Moderate

Neutral sentiment. Fair value pricing with moderate agreement suggests wait-and-see approach or catalyst-driven opportunity.

Market Sentiment Insight

Efficient pricing: Stock trading at fair value with strong consensus suggests market has priced in expectations. Look for fundamental inflection points or new catalysts to drive meaningful moves.

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Werewolf Therapeutics, Inc. Forward Estimates of Revenue

HOWL ยท NASDAQ
Latest Revenue
0.00
FY 2025
Avg Estimate
8.33M
FY 2026
Estimate Range
8.33M - 8.33M
Analyst Spread

Forward Growth Analysis

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookNeutral

Mixed signalsโ€”some positive indicators offset by concerns about growth or uncertainty.

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Werewolf Therapeutics, Inc. Forward Estimates of Net Income

HOWL ยท NASDAQ
Latest Net Income
-60.82M
FY 2025
Avg Estimate
-63.88M
FY 2026
Estimate Range
-73.31M - -54.44M
Analyst Spread

Forward Growth Analysis

Projected Growth-5.0%

Declining expectations indicate headwindsโ€”investigate whether temporary or structural issues.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread30%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

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Werewolf Therapeutics, Inc. Forward Estimates of EPS

HOWL ยท NASDAQ
Latest EPS
-1.32
FY 2025
Avg Estimate
$-1.41
FY 2026
Estimate Range
$-1.67 - $-1.24
Analyst Spread

Forward Growth Analysis

Projected Growth-6.6%

Declining expectations indicate headwindsโ€”investigate whether temporary or structural issues.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread31%

Moderate uncertainty in forecastsโ€”typical for companies with evolving business models.

OutlookCautious

Analyst skepticism evidentโ€”carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertaintyโ€”exercise caution.

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Werewolf Therapeutics, Inc. Forward Estimates of EBIT

HOWL ยท NASDAQ
Latest EBIT
-60.68M
FY 2025
Avg Estimate
-1.67M
FY 2026
Estimate Range
-1.67M - -1.67M
Analyst Spread

Forward Growth Analysis

Projected Growth+97.3%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Werewolf Therapeutics, Inc. Forward Estimates of EBITDA

HOWL ยท NASDAQ
Latest EBITDA
-59.04M
FY 2025
Avg Estimate
-1.67M
FY 2026
Estimate Range
-1.67M - -1.67M
Analyst Spread

Forward Growth Analysis

Projected Growth+97.2%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Werewolf Therapeutics, Inc. Forward Estimates of SG&A Expense

HOWL ยท NASDAQ
Latest SG&A Expense
15.85M
FY 2025
Avg Estimate
23.92M
FY 2026
Estimate Range
23.92M - 23.92M
Analyst Spread

Forward Growth Analysis

Projected Growth+50.9%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread0%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Werewolf Therapeutics, Inc. Insider Positioning

HOWL ยท NASDAQ

During the last 12 months, insiders have purchased $231K and sold $6.52M worth of HOWL shares, resulting in $6.29M of net selling activity.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

0

0.00

Sold

891.9K

635.04K

Net Activity

-635K

-$635K

6-9 Months

Bought

0

0.00

Sold

5.1M

5.89M

Net Activity

-5.9M

-$5.89M

9-12 Months

Bought

179.4K

230.83K

Sold

0

0.00

Net Activity

+231K

+$231K

Top Buyers

1
MB

Morrison Briggs

Director

27.0K sharesโ€ข1 transactions

$35K

2
LA

Lazarus Alon

Director

27.0K sharesโ€ข1 transactions

$35K

3
CM

Chatterjee Meeta

Director

27.0K sharesโ€ข1 transactions

$35K

4
EL

Evnin Luke

Director

27.0K sharesโ€ข1 transactions

$35K

5
SMA

Sherman Michael A.

Director

27.0K sharesโ€ข1 transactions

$35K

Top Sellers

1
MB2L

Mpm Bioventures 2014, L.P.

Other: Former 10% Owner

1.9M sharesโ€ข28 transactions

$2.22M

2
GA

Gadicke Ansbert

Other: Former 10% Owner

1.9M sharesโ€ข28 transactions

$2.22M

3
EL

Evnin Luke

Director

2.1M sharesโ€ข55 transactions

$2.08M

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $6.29M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.04:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Insider Participation

Moderate Buying

5 insider buyers vs. 3 sellers. More insiders buying than selling indicates positive sentiment.