Fractyl Health, Inc. Common Stock

Fractyl Health, Inc. Common Stock

GUTS·NASDAQ

$0.76

-3.1%
HealthcareBiotechnology

Fractyl Health, Inc., a metabolic therapeutics company, develops therapies for the treatment of type 2 diabetes (T2D) and obesity. The company develops Revita DMR System (Revita), an outpatient procedural therapy designed to durably modify duodenal dysfunction, a pathologic consequence of a high fat and high sugar diet, which can initiate T2D and obesity in humans. It also develops Rejuva, a novel virus delivered pancreatic gene therapy platform that is designed to enable long-term remission of T2D and obesity by durably altering metabolic hormone function in the pancreatic islet cells of patients. Fractyl Health, Inc. was formerly known as Fractyl Laboratories Inc. and changed its name to Fractyl Health, Inc. on June 09, 2021. The company was incorporated in 2010 and is based in Lexington, Massachusetts.

At a Glance

Live Snapshot
Market Cap$54.87M
EPS-1.8600
P/E Ratio-0.41
Earnings Date08/11/2026
-89.50%
Return on Invested Capital
-11%
3Y-1.0%
5Y-4.0%
10Y-83.0%
-1490.32%
Return on Equity
517%
3Y-8195.0%
5Y+631.0%
10Y-7115.0%
-116.11%
Return on Assets
83%
3Y+52.0%
5Y+32.0%
10Y-66.0%
Fractyl Health, Inc. Common Stock

Fractyl Health, Inc. Common Stock Management Team

GUTS · NASDAQ
ML

Ms. Lisa A. Davidson MBA

Chief Financial Officer & Treasurer

Compensation

$580,985

Born 1967(Age 59)
female
DT

Dr. Timothy J. Kieffer Ph.D.

Chief Scientific Officer

Compensation

$140,638

Born 1967(Age 59)
DH

Dr. Harith Rajagopalan M.D., Ph.D.

Co-Founder, Chief Executive Officer & Director

Compensation

$879,562

Born 1977(Age 49)
MJ

Mr. Jay D. Caplan BSEE, MBA

Co-Founder, Chief Product Officer & President

Compensation

$611,177

Born 1962(Age 64)
male
MS

Ms. Sarah S. Toomey Esq.

General Counsel & Corporate Secretary

Compensation

$479,363

Born 1975(Age 51)
female
MJ

Mr. Jon Fitzgerald

Senior Vice President of Regulatory, Quality & Clinical

male
MJ

Ms. Jessica Cotrone

Vice President of Corporate Communications

female
guts

Fractyl Health, Inc. Common Stock Insider Positioning

GUTS · NASDAQ

During the last 12 months, insiders have purchased $378K and sold $56K worth of GUTS shares, resulting in $322K of net buying activity.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

10.4K

20.00K

Sold

0

0.00

Net Activity

+20K

+$20K

9-12 Months

Bought

157.5K

357.52K

Sold

21.0K

55.99K

Net Activity

+302K

+$302K

Top Buyers

1
SAW

Schulman Amy W

Director

22.5K shares1 transactions

$51K

2
MC

Meanwell Clive

Director

22.5K shares1 transactions

$51K

3
BW

Bradley William

Director

22.5K shares1 transactions

$51K

4
BKA

Barnes Kelly Ann

Director

22.5K shares1 transactions

$51K

5
RA

Royan Ajay

Director, 10 Percent Owner:

22.5K shares1 transactions

$51K

Top Sellers

1
TCC

Thompson Christopher Charles

Director

21.0K shares1 transactions

$56K

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $322K net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

6.74:1

Exceptional buy/sell ratio. Buying dramatically outweighs selling—one of the strongest possible insider signals.

Insider Participation

High Buying

5 insider buyers vs. 1 sellers. Broad-based buying across management team suggests widespread confidence.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.

SEC Filings

GUTS - Filing history and reports

Filing TypeFiling DatePeriod EndingFiscal YearActions
DEF 14A

DEF 14A 2026

N/A

April 24, 2026
April 23, 2026
2026
DEF 14A

DEF 14A 2025

N/A

August 25, 2025
October 03, 2025
2025
DEF 14A

DEF 14A 2025

N/A

April 24, 2025
June 11, 2025
2025
Showing 1 to 3 of 3 filings