Fractyl Health, Inc. Common Stock

Fractyl Health, Inc. Common Stock

GUTS·NASDAQ

$0.79

+0.66%
HealthcareBiotechnology

Fractyl Health, Inc., a metabolic therapeutics company, develops therapies for the treatment of type 2 diabetes (T2D) and obesity. The company develops Revita DMR System (Revita), an outpatient procedural therapy designed to durably modify duodenal dysfunction, a pathologic consequence of a high fat and high sugar diet, which can initiate T2D and obesity in humans. It also develops Rejuva, a novel virus delivered pancreatic gene therapy platform that is designed to enable long-term remission of T2D and obesity by durably altering metabolic hormone function in the pancreatic islet cells of patients. Fractyl Health, Inc. was formerly known as Fractyl Laboratories Inc. and changed its name to Fractyl Health, Inc. on June 09, 2021. The company was incorporated in 2010 and is based in Lexington, Massachusetts.

At a Glance

Live Snapshot
Market Cap$57.02M
EPS-1.8600
P/E Ratio-0.42
Earnings Date08/11/2026
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Fractyl Health, Inc. Common Stock Street Expectations Map

GUTS · NASDAQ

Wall Street analysts project that GUTS stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 5.00, with estimates ranging from a low of 2.00 to a high of 8.00.

Lowest Target
2.00
153.23%
Consensus Target
5.00
533.07%
Highest Target
8.00
912.91%

The consensus 1-year price target stands at 5.00, with estimates ranging from a low of 2.00 to a high of 8.00.

Analyst Consensus Analysis

Upside Potential

+533.1%

Substantial upside potential. Analysts see significant value gap, suggesting the stock may be materially undervalued at current levels.

Analyst Agreement

120.0% spread

High uncertainty. Very wide target spread indicates significant disagreement among analysts—major valuation uncertainty or transformation underway.

Analyst Conviction

Low

High uncertainty: Wide dispersion indicates analysts struggle to agree on valuation—proceed with caution and independent analysis.

Market Sentiment Insight

High risk, high reward: Substantial upside potential exists, but wide analyst disagreement signals execution risk or unclear catalysts. Thorough due diligence essential before committing capital.

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Fractyl Health, Inc. Common Stock Forward Estimates of Revenue

GUTS · NASDAQ
Latest Revenue
0.00
FY 2025
Avg Estimate
12.43M
FY 2026
Estimate Range
9.39M - 17.55M
Analyst Spread

Forward Growth Analysis

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread66%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

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Fractyl Health, Inc. Common Stock Forward Estimates of Net Income

GUTS · NASDAQ
Latest Net Income
-140.95M
FY 2025
Avg Estimate
-28.56M
FY 2026
Estimate Range
-32.44M - -24.68M
Analyst Spread

Forward Growth Analysis

Projected Growth+79.7%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread27%

Moderate uncertainty in forecasts—typical for companies with evolving business models.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Fractyl Health, Inc. Common Stock Forward Estimates of EPS

GUTS · NASDAQ
Latest EPS
-1.86
FY 2025
Avg Estimate
$-0.37
FY 2026
Estimate Range
$-0.43 - $-0.33
Analyst Spread

Forward Growth Analysis

Projected Growth+80.0%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread28%

Moderate uncertainty in forecasts—typical for companies with evolving business models.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Fractyl Health, Inc. Common Stock Forward Estimates of EBIT

GUTS · NASDAQ
Latest EBIT
-96.82M
FY 2025
Avg Estimate
2.49M
FY 2026
Estimate Range
1.88M - 3.51M
Analyst Spread

Forward Growth Analysis

Projected Growth+102.6%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread66%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Fractyl Health, Inc. Common Stock Forward Estimates of EBITDA

GUTS · NASDAQ
Latest EBITDA
-95.69M
FY 2025
Avg Estimate
2.49M
FY 2026
Estimate Range
1.88M - 3.51M
Analyst Spread

Forward Growth Analysis

Projected Growth+102.6%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread66%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookNeutral

Mixed signals—some positive indicators offset by concerns about growth or uncertainty.

Key Insight

Limited coverage with volatile estimates: Few analysts covering despite significant projected changes may indicate information gaps or emerging risks.

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Fractyl Health, Inc. Common Stock Forward Estimates of SG&A Expense

GUTS · NASDAQ
Latest SG&A Expense
21.15M
FY 2025
Avg Estimate
7.46M
FY 2026
Estimate Range
5.63M - 10.53M
Analyst Spread

Forward Growth Analysis

Projected Growth-64.7%

Significant contraction projected—major business challenges or industry disruption likely.

Analyst Coverage3 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread66%

Wide estimate range reveals significant forecast uncertainty and potential volatility.

OutlookCautious

Analyst skepticism evident—carefully evaluate risks before investment decisions.

Key Insight

Declining estimates with wide disagreement: Analysts projecting contraction without consensus signals significant business uncertainty—exercise caution.

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Fractyl Health, Inc. Common Stock Insider Positioning

GUTS · NASDAQ

During the last 12 months, insiders have purchased $378K and sold $56K worth of GUTS shares, resulting in $322K of net buying activity.

3 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

3-6 Months

Bought

0

0.00

Sold

0

0.00

Net Activity

+0

+$0

6-9 Months

Bought

10.4K

20.00K

Sold

0

0.00

Net Activity

+20K

+$20K

9-12 Months

Bought

157.5K

357.52K

Sold

21.0K

55.99K

Net Activity

+302K

+$302K

Top Buyers

1
SAW

Schulman Amy W

Director

22.5K shares1 transactions

$51K

2
MC

Meanwell Clive

Director

22.5K shares1 transactions

$51K

3
BW

Bradley William

Director

22.5K shares1 transactions

$51K

4
BKA

Barnes Kelly Ann

Director

22.5K shares1 transactions

$51K

5
RA

Royan Ajay

Director, 10 Percent Owner:

22.5K shares1 transactions

$51K

Top Sellers

1
TCC

Thompson Christopher Charles

Director

21.0K shares1 transactions

$56K

Insider Activity Analysis

Net Insider Sentiment

Bullish

Strong bullish signal with $322K net buying. Insiders are aggressively accumulating shares, suggesting significant confidence in future prospects.

Buy/Sell Ratio

6.74:1

Exceptional buy/sell ratio. Buying dramatically outweighs selling—one of the strongest possible insider signals.

Insider Participation

High Buying

5 insider buyers vs. 1 sellers. Broad-based buying across management team suggests widespread confidence.

Insider Activity Insight

Compelling insider conviction: The combination of strong buy/sell ratio and multiple buyers suggests insiders see attractive risk/reward. Consider this alongside fundamental analysis for confirmation.