GRAIL, Inc.

GRAIL, Inc.

GRAL·NASDAQ

$66.93

+9.5%
HealthcareMedical - Diagnostics & Research

GRAIL, Inc., a biotechnology company, focuses on developing technologies for early cancer detection. The company develops Galleri, a screening test for asymptomatic individuals over 50 years of age; and DAC, a diagnostic aid for cancer tests to accelerate diagnostic resolution for patients for whom there is a clinical suspicion of cancer. It is also developing minimal residual disease and other post-diagnostic tests. The company was incorporated in 2015 and is based in Menlo Park, California. GRAIL, Inc. operates as a former subsidiary of Illumina, Inc.

At a Glance

Live Snapshot
Market Cap$2.87B
EPS-11.1100
P/E Ratio-6.02
Earnings Date08/11/2026
gral

GRAIL, Inc. Street Expectations Map

GRAL · NASDAQ

Wall Street analysts project that GRAL stock may rise significantly over the coming 12 months. The consensus 1-year price target stands at 75.67, with estimates ranging from a low of 56.00 to a high of 130.00.

Lowest Target
56.00
-16.34%
Consensus Target
75.67
13.05%
Highest Target
130.00
94.22%

The consensus 1-year price target stands at 75.67, with estimates ranging from a low of 56.00 to a high of 130.00.

Analyst Consensus Analysis

Upside Potential

+13.1%

Moderate upside. Analysts expect positive returns but with limited margin of safety. Consider entry timing.

Analyst Agreement

97.8% spread

High uncertainty. Very wide target spread indicates significant disagreement among analysts—major valuation uncertainty or transformation underway.

Risk-Reward Profile

5.77x

Favorable risk-reward. Potential upside significantly exceeds downside risk, offering asymmetric return profile attractive for risk-tolerant investors.

Analyst Conviction

Low

High uncertainty: Wide dispersion indicates analysts struggle to agree on valuation—proceed with caution and independent analysis.

Market Sentiment Insight

Extreme uncertainty: Massive dispersion in price targets reflects fundamental disagreement on business trajectory. This could signal transformation, disruption, or complex valuation—requires deep sector expertise and contrarian mindset.

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GRAIL, Inc. Forward Estimates of Revenue

GRAL · NASDAQ
Latest Revenue
147.17M
FY 2025
Avg Estimate
180.15M
FY 2026
Estimate Range
172.22M - 184.49M
Analyst Spread

Forward Growth Analysis

Projected Growth+22.4%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage6 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread7%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

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GRAIL, Inc. Forward Estimates of Net Income

GRAL · NASDAQ
Latest Net Income
-408.35M
FY 2025
Avg Estimate
-393.20M
FY 2026
Estimate Range
-402.84M - -383.55M
Analyst Spread

Forward Growth Analysis

Projected Growth+3.7%

Flat growth suggests market maturity or near-term challenges offsetting expansion efforts.

Analyst Coverage6 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread5%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

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GRAIL, Inc. Forward Estimates of EPS

GRAL · NASDAQ
Latest EPS
-11.11
FY 2025
Avg Estimate
$-10.68
FY 2026
Estimate Range
$-10.96 - $-10.44
Analyst Spread

Forward Growth Analysis

Projected Growth+3.9%

Flat growth suggests market maturity or near-term challenges offsetting expansion efforts.

Analyst Coverage4 Analysts

Limited coverage may indicate reduced institutional interest or information availability.

Estimate Spread5%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookPositive

Generally favorable outlook with reasonable growth prospects and analyst support.

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GRAIL, Inc. Forward Estimates of EBIT

GRAL · NASDAQ
Latest EBIT
-534.16M
FY 2025
Avg Estimate
-180.15M
FY 2026
Estimate Range
-184.49M - -172.22M
Analyst Spread

Forward Growth Analysis

Projected Growth+66.3%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage6 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread7%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

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GRAIL, Inc. Forward Estimates of EBITDA

GRAL · NASDAQ
Latest EBITDA
-377.82M
FY 2025
Avg Estimate
-180.15M
FY 2026
Estimate Range
-184.49M - -172.22M
Analyst Spread

Forward Growth Analysis

Projected Growth+52.3%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage6 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread7%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

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GRAIL, Inc. Forward Estimates of SG&A Expense

GRAL · NASDAQ
Latest SG&A Expense
275.80M
FY 2025
Avg Estimate
1.08B
FY 2026
Estimate Range
1.04B - 1.11B
Analyst Spread

Forward Growth Analysis

Projected Growth+292.6%

Strong growth expectations signal robust business momentum and market opportunity expansion.

Analyst Coverage6 Analysts

Moderate coverage—sufficient for guidance but may lack depth of large-cap analysis.

Estimate Spread7%

Narrow estimate range signals strong analyst consensus and predictable business outlook.

OutlookStrong

Positive analyst consensus with strong growth expectations and forecast confidence.

Key Insight

Compelling growth story with analyst consensus: Strong projected growth combined with narrow estimate spread suggests high-conviction opportunity.

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GRAIL, Inc. Insider Positioning

GRAL · NASDAQ

During the last 12 months, insiders have sold $104.57M worth of GRAL shares, with no buying activity reported.

3 Months

Bought

0

0.00

Sold

233.4K

11.64M

Net Activity

-11.6M

-$11.64M

3-6 Months

Bought

0

0.00

Sold

1.4K

75.03K

Net Activity

-75K

-$75K

6-9 Months

Bought

0

0.00

Sold

1.1M

90.06M

Net Activity

-90.1M

-$90.06M

9-12 Months

Bought

0

0.00

Sold

60.3K

2.79M

Net Activity

-2.8M

-$2.79M

Top Buyers

No buying activity

Top Sellers

1
II

Illumina, Inc.

10 Percent Owner

1.0M shares1 transactions

$79.85M

2
OJJ

Ofman Joshua J.

Director, Officer: President

205.1K shares10 transactions

$12.35M

3
RRP

Ragusa Robert P

Director, Officer: Chief Executive Officer

145.5K shares3 transactions

$8.06M

4
FA

Freidin Aaron

Officer: Chief Financial Officer

59.4K shares6 transactions

$2.91M

5
DCR

Ding Chun R

10 Percent Owner

27.8K shares1 transactions

$1.40M

Insider Activity Analysis

Net Insider Sentiment

Bearish

Strong bearish signal with $104.57M net selling. Heavy insider selling may indicate concerns about valuation or near-term prospects.

Buy/Sell Ratio

0.00:1

Very poor ratio. Heavy selling with minimal buying suggests insiders may be concerned about valuation or outlook.

Recent Trend (3 Months)

$11.64M

Heavy recent selling activity. Recent insider sales notably exceed purchases—may warrant investigation into company developments.

Insider Participation

High Selling

5 insider sellers vs. 0 buyers. Widespread selling across multiple insiders may signal concerns.

Insider Activity Insight

Multiple red flags: Heavy selling, numerous sellers, and continued recent selling create a concerning pattern. Investigate fundamental drivers and consider whether company guidance or industry conditions have deteriorated.